| RS750331066 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 1, Joubert syndrome |
| RS750331217 |
FBN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS750331613 |
GRID2
|
Health Risk |
Pathogenic |
Autosomal recessive spinocerebellar ataxia 18, Autosomal recessive spinocerebellar ataxia 18 |
| RS750332447 |
NPHS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 2 |
| RS750334480 |
DOCK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 23 |
| RS750335388 |
RAI1
|
Health Risk |
Pathogenic |
— |
| RS750335577 |
SOD1
|
Health Risk |
Likely pathogenic |
Amyotrophic lateral sclerosis type 1, Amyotrophic lateral sclerosis type 1 |
| RS750336865 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750337451 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteofibrous dysplasia, Hereditary cancer-predisposing syndrome |
| RS750338004 |
STAT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection, Inborn genetic diseases |
| RS750338018 |
CYP19A1
|
Health Risk |
Likely pathogenic |
— |
| RS750338419 |
IFT172
|
Health Risk |
Pathogenic/Likely pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 10 with or without polydactyly |
| RS750339037 |
MTHFR
|
Health Risk |
Likely pathogenic |
Neural tube defects, folate-sensitive |
| RS750340477 |
PRPF31
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 11, Retinal dystrophy |
| RS75034086 |
CHSY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Temtamy preaxial brachydactyly syndrome, Inborn genetic diseases |
| RS750341436 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS750342865 |
CD46
|
Health Risk |
Conflicting classifications of pathogenicity |
Atypical hemolytic-uremic syndrome, Atypical hemolytic-uremic syndrome |
| RS750343039 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS750343121 |
LRPPRC
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS750343369 |
PCCB
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS750344996 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS750345068 |
DHCR7
|
Health Risk |
Pathogenic/Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS750345987 |
COL4A4
|
Health Risk |
Pathogenic |
Autosomal dominant Alport syndrome, Autosomal dominant Alport syndrome |
| RS750346186 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS750349082 |
XYLT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Osteogenesis imperfecta |
| RS750349088 |
KCNE1
|
Health Risk |
Likely pathogenic |
Long QT syndrome 5, Long QT syndrome 5 |
| RS750349377 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS750349613 |
DMD
|
Health Risk |
Likely pathogenic |
Primary familial hypertrophic cardiomyopathy, Duchenne muscular dystrophy |
| RS750350372 |
BARD1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS750350575 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 11 |
| RS750350692 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 2, primary |
| RS750353040 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750353391 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750353606 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS750354456 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Inborn genetic diseases |
| RS750354519 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, FLNB-Related Spectrum Disorders |
| RS750355280 |
MPDZ
|
Health Risk |
Likely pathogenic |
Hydrocephalus, nonsyndromic |
| RS750355699 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome |
| RS750356247 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Distal myopathy with anterior tibial onset |
| RS750357326 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS750357369 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS750358148 |
MYO7A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome, Autosomal recessive nonsyndromic hearing loss 2 |
| RS750359968 |
SAMHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Aicardi-Goutieres syndrome 5 |
| RS750360032 |
UBE3B
|
Health Risk |
Pathogenic/Likely pathogenic |
Oculocerebrofacial syndrome, Kaufman type |
| RS75036167 |
SLC7A9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystinuria, Cystinuria |
| RS750362154 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Familial Mediterranean fever |
| RS750362416 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750362675 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750363004 |
BTD
|
Health Risk |
Pathogenic/Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS750363970 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS750364111 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 16, Paramyotonia congenita of Von Eulenburg |
| RS750364303 |
BUB1B
|
Health Risk |
Pathogenic |
Mosaic variegated aneuploidy syndrome 1, Mosaic variegated aneuploidy syndrome 1 |
| RS750364485 |
VWF
|
Health Risk |
Pathogenic |
von Willebrand disease type 3, von Willebrand disease type 3 |
| RS750364705 |
SCN1A
|
Health Risk |
Pathogenic |
Early-infantile DEE, Developmental and epileptic encephalopathy |
| RS750365180 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Autosomal recessive nonsyndromic hearing loss 4 |
| RS750366331 |
MSH3
|
Health Risk |
Pathogenic |
Endometrial carcinoma, Hereditary cancer-predisposing syndrome |
| RS750367160 |
ZC4H2
|
Health Risk |
Likely pathogenic |
Wieacker-Wolff syndrome, Wieacker-Wolff syndrome |
| RS750368181 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750368565 |
PHGDH
|
Health Risk |
Pathogenic |
PHGDH deficiency, PHGDH deficiency |
| RS750368652 |
DOLK
|
Health Risk |
Conflicting classifications of pathogenicity |
DK1-congenital disorder of glycosylation, Cardiovascular phenotype |
| RS750368911 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750368946 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 39, Usher syndrome |
| RS750369135 |
KIZ
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 69, Retinitis pigmentosa 69 |
| RS750371292 |
TSFM
|
Health Risk |
Pathogenic/Likely pathogenic |
Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3, Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3 |
| RS750371433 |
SLX4
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group P, Fanconi anemia |
| RS750371878 |
HACE1
|
Health Risk |
Pathogenic |
Spastic paraplegia-severe developmental delay-epilepsy syndrome, Seizure |
| RS750372409 |
SUMF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple sulfatase deficiency, Multiple sulfatase deficiency |
| RS750372510 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS750373166 |
CNGB1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 45, Retinitis pigmentosa 45 |
| RS750373262 |
NPHS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephrotic syndrome, type 2 |
| RS750373573 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS750373957 |
CAVIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital generalized lipodystrophy type 4, CAVIN1-related disorder |
| RS750374337 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 22, Autosomal recessive nonsyndromic hearing loss 37 |
| RS750374521 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS750374714 |
FREM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculotrichoanal syndrome, Oculotrichoanal syndrome |
| RS750375727 |
SHOX
|
Health Risk |
Conflicting classifications of pathogenicity |
SHOX-related disorder, SHOX-related disorder |
| RS750375741 |
NBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS750376392 |
MEIOB
|
Health Risk |
Pathogenic |
Spermatogenic failure 22, Premature ovarian failure 23 |
| RS750377065 |
OCRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Lowe syndrome, Lowe syndrome |
| RS750377910 |
AP3B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 2, Hermansky-Pudlak syndrome 2 |
| RS750380279 |
SDHA
|
Health Risk |
Pathogenic |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS750381200 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS750381445 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Saldino-Mainzer syndrome |
| RS750381568 |
DMAP1
|
Health Risk |
Likely pathogenic |
Intellectual disability, Abnormal facial shape |
| RS750381895 |
MTRR
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylcobalamin deficiency type cblE, Methylcobalamin deficiency type cblE |
| RS750383066 |
SUZ12
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Imagawa-Matsumoto syndrome |
| RS750383461 |
LDLRAP1
|
Health Risk |
Pathogenic |
Hypercholesterolemia, familial |
| RS750383545 |
AHI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 3 |
| RS750383681 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS750384225 |
GLDC
|
Health Risk |
Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS750384699 |
GATA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness-lymphedema-leukemia syndrome, Monocytopenia with susceptibility to infections |
| RS750385844 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS750386872 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Norman-Roberts syndrome |
| RS750388638 |
LAMA3
|
Health Risk |
Likely pathogenic |
— |
| RS750388794 |
SUCLG1
|
Health Risk |
Likely pathogenic |
Mitochondrial DNA depletion syndrome 9, Melanoma |
| RS750389762 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750390186 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750390328 |
LIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
DNA ligase IV deficiency, Inborn genetic diseases |
| RS750390370 |
SOX11
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750393216 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |