| RS750201480 |
QDPR
|
Health Risk |
Pathogenic/Likely pathogenic |
Dihydropteridine reductase deficiency, Dihydropteridine reductase deficiency |
| RS750203389 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS750203541 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS750203675 |
NEU1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750203677 |
COL1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Osteogenesis imperfecta type I |
| RS750204106 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS7502059 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS750206820 |
SLC35A3
|
Health Risk |
Pathogenic |
Autism spectrum disorder - epilepsy - arthrogryposis syndrome, Autism spectrum disorder - epilepsy - arthrogryposis syndrome |
| RS750207077 |
TDRD7
|
Health Risk |
Pathogenic |
Cataract 36, Cataract 36 |
| RS750209664 |
SCN1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS750210485 |
SORD
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS750211727 |
DHCR7
|
Health Risk |
Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS750212705 |
FANCG
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group G |
| RS750212973 |
PHYH
|
Health Risk |
Pathogenic |
— |
| RS750213029 |
LZTR1
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS750213547 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, TTN-related disorder |
| RS750214113 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750214208 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS750214431 |
ASS1
|
Health Risk |
Pathogenic |
Citrullinemia type I, Citrullinemia |
| RS750214847 |
ABCA12
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 4A, Autosomal recessive congenital ichthyosis 4A |
| RS750215526 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 5, Cranioectodermal dysplasia 4 |
| RS750215904 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS750216083 |
SVBP
|
Health Risk |
Likely pathogenic |
SVBP-related disorder, SVBP-related disorder |
| RS750216784 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Rubinstein-Taybi syndrome |
| RS750217875 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS750218942 |
XPA
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum |
| RS750219200 |
RAD51D
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS750219615 |
LSM7
|
Health Risk |
Pathogenic |
Leukodystrophy, LSM7-related leukodystrophy and cerebellar atrophy |
| RS750219987 |
RSPH4A
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750220338 |
CYP1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital glaucoma, Congenital glaucoma |
| RS750220830 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS750221380 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome 1, Hereditary cancer-predisposing syndrome |
| RS750221808 |
MNS1
|
Health Risk |
Likely pathogenic |
Heterotaxy, visceral |
| RS750222217 |
CC2D1A
|
Health Risk |
Pathogenic |
— |
| RS750222574 |
CNGB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 45, Retinitis pigmentosa 45 |
| RS750224234 |
ATM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750225476 |
SPINK5
|
Health Risk |
Pathogenic |
Netherton syndrome, Netherton syndrome |
| RS750225643 |
SLC25A13
|
Health Risk |
Pathogenic |
Citrin deficiency, Citrin deficiency |
| RS750225817 |
CNGB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 45 |
| RS750226076 |
GALT
|
Health Risk |
Likely pathogenic |
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase, Galactosemia |
| RS750226213 |
UNC80
|
Health Risk |
Pathogenic |
Hypotonia, infantile |
| RS750227063 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750227698 |
VWA1
|
Health Risk |
Pathogenic |
— |
| RS750227810 |
OFD1
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Orofaciodigital syndrome I |
| RS750227861 |
KCNJ10
|
Health Risk |
Conflicting classifications of pathogenicity |
EAST syndrome, EAST syndrome |
| RS750228923 |
USH2A
|
Health Risk |
Pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS750229142 |
ZMPSTE24
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS75022916 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750229518 |
PTS;TEX12
|
Health Risk |
Pathogenic/Likely pathogenic |
6-Pyruvoyl-tetrahydrobiopterin synthase deficiency, 6-Pyruvoyl-tetrahydrobiopterin synthase deficiency |
| RS750230820 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750231498 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS750232956 |
MYH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, proximal |
| RS750233571 |
PNPLA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutral lipid storage myopathy, Neutral lipid storage myopathy |
| RS75023630 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS750236367 |
MAN1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rafiq syndrome, Rafiq syndrome |
| RS750237658 |
TOPORS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 31 |
| RS750238787 |
CR2
|
Health Risk |
Pathogenic |
Immunodeficiency, common variable |
| RS750239776 |
ZNF142
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with impaired speech and hyperkinetic movements, Neurodevelopmental disorder with impaired speech and hyperkinetic movements |
| RS750240374 |
GNPTAB
|
Health Risk |
Likely pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS750242131 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS750242979 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Familial cancer of breast |
| RS750245108 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS750245529 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750247163 |
MED23
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 18 |
| RS750247691 |
ARMC9
|
Health Risk |
Conflicting classifications of pathogenicity |
ARMC9-related Joubert syndrome, Joubert syndrome 30 |
| RS750249747 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS750249796 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS750249799 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 7, Cardiovascular phenotype |
| RS750251152 |
NEFL
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 1F, Charcot-Marie-Tooth disease |
| RS750251384 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS750252271 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS750253749 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750254727 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS750255126 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750255359 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS750255505 |
EMC1
|
Health Risk |
Likely pathogenic |
— |
| RS750256116 |
CTCF
|
Health Risk |
Likely pathogenic |
CTCF-related neurodevelopmental disorder, CTCF-related neurodevelopmental disorder |
| RS750256343 |
CPLANE1
|
Health Risk |
Pathogenic |
— |
| RS750257554 |
CNGB3
|
Health Risk |
Likely pathogenic |
Achromatopsia, Achromatopsia 3 |
| RS750257902 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS750258633 |
BBS4
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 4 |
| RS750258756 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Primary dilated cardiomyopathy |
| RS750259620 |
RAB18
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750260160 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS750260341 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Vesicoureteral reflux 8 |
| RS750260438 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS750260671 |
WNT10A
|
Health Risk |
Pathogenic/Likely pathogenic |
Odonto-onycho-dermal dysplasia, Tooth agenesis |
| RS750261457 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750261857 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Hereditary cancer-predisposing syndrome |
| RS750262029 |
COL7A1
|
Health Risk |
Pathogenic |
— |
| RS750262940 |
DOK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 10, Fetal akinesia deformation sequence 1 |
| RS750264224 |
AGXT
|
Health Risk |
Pathogenic |
Primary hyperoxaluria, type I |
| RS750264231 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome |
| RS750264813 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 77, Autosomal recessive nonsyndromic hearing loss 77 |
| RS750264852 |
KCNH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750265350 |
BMPER
|
Health Risk |
Conflicting classifications of pathogenicity |
Diaphanospondylodysostosis, Diaphanospondylodysostosis |
| RS750265500 |
PPP2R5D
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750265990 |
RNASET2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic leukoencephalopathy without megalencephaly, Cystic leukoencephalopathy without megalencephaly |
| RS750266004 |
SYNE1
|
Health Risk |
Pathogenic |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS750266350 |
TOE1
|
Health Risk |
Likely pathogenic |
Pontocerebellar hypoplasia type 7, TOE1-related disorder |