| RS750393418 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750394268 |
VAPB
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 8, Adult-onset proximal spinal muscular atrophy |
| RS750394475 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Familial spontaneous pneumothorax |
| RS750396156 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 39 |
| RS750396637 |
EVC2
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Ellis-van Creveld syndrome |
| RS75039782 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Hereditary pancreatitis |
| RS750398883 |
FBXO7
|
Health Risk |
Pathogenic |
Parkinsonian-pyramidal syndrome, Parkinsonian-pyramidal syndrome |
| RS75039907 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Retinal dystrophy |
| RS750399134 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750399917 |
STAT5B
|
Health Risk |
Likely pathogenic |
Growth hormone insensitivity with immune dysregulation 1, autosomal recessive |
| RS750400501 |
BCAT2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750401200 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS750402363 |
HPS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome |
| RS750402920 |
CTNNB1
|
Health Risk |
Pathogenic |
Severe intellectual disability-progressive spastic diplegia syndrome, Severe intellectual disability-progressive spastic diplegia syndrome |
| RS750404000 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS750404832 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS750405773 |
IGFALS
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature due to primary acid-labile subunit deficiency, Short stature due to primary acid-labile subunit deficiency |
| RS750406193 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS750407488 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS750407517 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease axonal type 2S |
| RS750408092 |
RAB34
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Orofaciodigital syndrome 20 |
| RS750408108 |
BLK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750409379 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 1 |
| RS750410479 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 17, Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss |
| RS750410843 |
ENPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypophosphatemic rickets, autosomal recessive |
| RS750411964 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome |
| RS750413238 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Parkinsonian disorder, Inborn genetic diseases |
| RS750413412 |
EIF2B4
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS750413473 |
BARD1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS750414160 |
KCNJ11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS750415021 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS750415265 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 10, Spastic paraplegia |
| RS750416999 |
C5
|
Health Risk |
Likely pathogenic |
Complement component 5 deficiency, Eculizumab |
| RS750417849 |
TRAPPC6B
|
Health Risk |
Pathogenic |
— |
| RS750418747 |
PIGN
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 1, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS750418813 |
AIFM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth Neuropathy X, Combined oxidative phosphorylation deficiency |
| RS750419527 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS750419825 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spondylometaphyseal dysplasia - Sutcliffe type, Glomerulopathy with fibronectin deposits 2 |
| RS750420028 |
ATP6V0A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal renal tubular acidosis, Autosomal recessive distal renal tubular acidosis |
| RS750420071 |
ASNS
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome, Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome |
| RS750420130 |
MUC16
|
Health Risk |
Likely pathogenic |
Ovarian cancer, Ovarian cancer |
| RS750421671 |
RASA1
|
Health Risk |
Likely pathogenic |
Capillary malformation-arteriovenous malformation syndrome, Nonpapillary renal cell carcinoma |
| RS750421791 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS750422335 |
PGAM2
|
Health Risk |
Likely pathogenic |
Rhabdomyolysis, Rhabdomyolysis |
| RS750424357 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Dilated cardiomyopathy 1G |
| RS750424494 |
SLC12A1
|
Health Risk |
Pathogenic |
— |
| RS750425112 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
FBN2-related disorder, Congenital contractural arachnodactyly |
| RS750425291 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS750425667 |
CDK13
|
Health Risk |
Conflicting classifications of pathogenicity |
CDK13-related disorder, CDK13-related disorder |
| RS750427423 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS750427647 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS750428278 |
CYP11B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of steroid 11-beta-monooxygenase, Deficiency of steroid 11-beta-monooxygenase |
| RS750428882 |
TPP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronal ceroid lipofuscinosis 2, Inborn genetic diseases |
| RS750429255 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Atelosteogenesis type I, Inborn genetic diseases |
| RS750430725 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS750430784 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, LRP2-related disorder |
| RS750431739 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS750431938 |
ASL
|
Health Risk |
Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS750433247 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, RASopathy |
| RS750433723 |
RARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontocerebellar hypoplasia type 6, Congenital cerebellar hypoplasia |
| RS750433951 |
SMPD1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type A |
| RS750435043 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750435648 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS750436246 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS750436297 |
RAB3GAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Martsolf syndrome, Warburg micro syndrome 2 |
| RS750436680 |
B9D2
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Joubert syndrome 34 |
| RS750438076 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS750439376 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750440690 |
PANK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS750441093 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Inborn genetic diseases |
| RS750441217 |
SLC5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial renal glucosuria, Inborn genetic diseases |
| RS750441497 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS750441954 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS750442312 |
CRB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Leber congenital amaurosis 8 |
| RS750442854 |
UNC80
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental delay, Neurodevelopmental delay |
| RS750443041 |
CAPN3
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS750443621 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Singleton-Merten syndrome 1, Aicardi-Goutieres syndrome 7 |
| RS750443804 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS750444649 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS750444774 |
SRD5A2
|
Health Risk |
Pathogenic |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS750444836 |
SALL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Townes syndrome, Inborn genetic diseases |
| RS750447037 |
ARID1B
|
Health Risk |
Pathogenic |
Coffin-Siris syndrome 1, Coffin-Siris syndrome 1 |
| RS750447792 |
FH
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary leiomyomatosis and renal cell cancer |
| RS750447828 |
HSPA1L
|
Health Risk |
association |
Inflammatory bowel disease 1, Inflammatory bowel disease 1 |
| RS750447918 |
CYP1B1
|
Health Risk |
Likely pathogenic |
Anterior segment dysgenesis 6, Anterior segment dysgenesis 6 |
| RS750448421 |
PJVK
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 59, Autosomal recessive nonsyndromic hearing loss 59 |
| RS750448899 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS750449050 |
FAM161A
|
Health Risk |
Pathogenic |
— |
| RS750450365 |
XPC
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group C |
| RS750450803 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750451480 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS750451693 |
CP
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Deficiency of ferroxidase |
| RS750451819 |
ALG1
|
Health Risk |
Pathogenic/Likely pathogenic |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS750451843 |
TAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly-thin corpus callosum-intellectual disability syndrome, Microcephaly-thin corpus callosum-intellectual disability syndrome |
| RS750452808 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome, Usher syndrome |
| RS750453538 |
UGT1A1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS750453761 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Progressive familial heart block type IB |
| RS750453909 |
POMT1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS750456621 |
CNGA3
|
Health Risk |
Likely pathogenic |
— |
| RS750457181 |
ACVR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |