BCAT2 Chromosome 19

Branched chain amino acid transaminase 2
8 variants 8 Health Risk

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What This Gene Does
This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Info
Gene Group
"Minor histocompatibility antigens|Branched chain amino acid transaminase family"
Locus Type
gene with protein product
Location
19q13.33
Ensembl
ENSG00000105552
Associated Conditions (1)
Hypervalinemia and hyperleucine-isoleucinemia
Key Variants
All Variants (8)
RSID Category Clinical Significance Conditions
RS145231743 Health Risk Conflicting classifications of pathogenicity
RS150646107 Health Risk Conflicting classifications of pathogenicity
RS750400501 Health Risk Conflicting classifications of pathogenicity
RS2514085671 Health Risk Likely pathogenic
RS749866079 Health Risk Pathogenic Hypervalinemia and hyperleucine-isoleucinemia, Hypervalinemia and hyperleucine-isoleucinemia
RS753659619 Health Risk Pathogenic Hypervalinemia and hyperleucine-isoleucinemia, Hypervalinemia and hyperleucine-isoleucinemia
RS767653663 Health Risk Pathogenic Hypervalinemia and hyperleucine-isoleucinemia, Hypervalinemia and hyperleucine-isoleucinemia
RS755640785 Health Risk Pathogenic/Likely pathogenic Hypervalinemia and hyperleucine-isoleucinemia, Hypervalinemia and hyperleucine-isoleucinemia
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