| RS750593383 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS750594210 |
ACSF3
|
Health Risk |
Pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS750594279 |
LRP6
|
Health Risk |
Pathogenic |
— |
| RS750594314 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS750594890 |
DBT
|
Health Risk |
Pathogenic |
Maple syrup urine disease, Maple syrup urine disease type 2 |
| RS750595555 |
NUP62
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750596095 |
RNF213
|
Health Risk |
risk factor |
Moyamoya disease 2, Moyamoya disease 2 |
| RS750596755 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS750596783 |
MLH1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750597831 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS750598605 |
ERCC6
|
Health Risk |
Pathogenic |
— |
| RS750599200 |
PDE6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 40, Retinitis pigmentosa 40 |
| RS750599225 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS750599959 |
PCDH19
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 9 |
| RS750600448 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS750600586 |
TP53
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS750602133 |
TRIP11
|
Health Risk |
Pathogenic |
Achondrogenesis, type IA |
| RS750603177 |
DNAAF11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 19, Primary ciliary dyskinesia 19 |
| RS750603454 |
TFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hereditary hemochromatosis |
| RS750604350 |
CPT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine palmitoyltransferase II deficiency, Carnitine palmitoyltransferase II deficiency |
| RS750604586 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750606223 |
HBB
|
Health Risk |
Pathogenic |
beta Thalassemia, beta Thalassemia |
| RS750607476 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS750608792 |
SPINK5
|
Health Risk |
Conflicting classifications of pathogenicity |
Netherton syndrome, Ichthyosis linearis circumflexa |
| RS750609110 |
CTSK
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750609245 |
CNGB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CNGB1-related disorder |
| RS750609612 |
VPS13B
|
Health Risk |
Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS750609759 |
TFR2
|
Health Risk |
Pathogenic |
Hereditary hemochromatosis, Hemochromatosis type 3 |
| RS750610043 |
SLC25A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Citrin deficiency, Citrin deficiency |
| RS750610201 |
ELANE
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutropenia, severe congenital |
| RS750610248 |
BCL11B
|
Health Risk |
Pathogenic |
Combined immunodeficiency, Immunodeficiency 49 |
| RS750610377 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750610720 |
ACOX1
|
Health Risk |
Pathogenic |
Acyl-CoA oxidase deficiency, Acyl-CoA oxidase deficiency |
| RS750610895 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750611000 |
BBS10
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 10 |
| RS750611719 |
IL12RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency |
| RS750612085 |
LINGO1
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 64 |
| RS750614475 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease |
| RS750614500 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, ADSL-related disorder |
| RS750615873 |
FRMPD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750616133 |
CEP135
|
Health Risk |
Pathogenic |
— |
| RS750616657 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS750617137 |
C9
|
Health Risk |
Pathogenic |
— |
| RS750617462 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750618265 |
EXOSC9
|
Health Risk |
Pathogenic |
— |
| RS750618617 |
MC1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Melanoma, cutaneous malignant |
| RS750618688 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Hypertrophic cardiomyopathy |
| RS750618829 |
ARID1A
|
Health Risk |
Pathogenic |
Malignant tumor of urinary bladder, Malignant tumor of urinary bladder |
| RS750619189 |
MMUT
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to complete methylmalonyl-CoA mutase deficiency |
| RS750619309 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Transitory neonatal diabetes mellitus |
| RS750620293 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome, Brain small vessel disease 1 with or without ocular anomalies |
| RS750620302 |
CNGB1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS750620615 |
POMGNT1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A3 |
| RS750621192 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS750621215 |
RAD51D
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS750621529 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS750622215 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS750622312 |
ALPK3
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS750623875 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive spinocerebellar ataxia 14, Autosomal recessive spinocerebellar ataxia 14 |
| RS750623911 |
ARL6IP1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 61, ARL6IP1-related disorder |
| RS750624029 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS750624044 |
TRPV6
|
Health Risk |
Likely pathogenic |
Hyperparathyroidism, transient neonatal |
| RS750625862 |
TJP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750628677 |
PHKA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXa1, Inborn genetic diseases |
| RS750630131 |
AUTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750631177 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750632206 |
CCM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cerebral cavernous malformation 2 |
| RS750633804 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750633919 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS750636662 |
RDH12
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 13, Macular dystrophy |
| RS750636989 |
PIGO
|
Health Risk |
Pathogenic |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS750637537 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS750637713 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hemorrhagic telangiectasia, Telangiectasia |
| RS750638027 |
SHOX
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750638943 |
ALDH5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS750639988 |
LCA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS750640009 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS750640150 |
BCORL1
|
Health Risk |
Pathogenic |
Oligoasthenoteratozoospermia, Oligoasthenoteratozoospermia |
| RS750640740 |
DNAH11
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS750640802 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dystrophin deficiency |
| RS750641485 |
TUBGCP4
|
Health Risk |
Pathogenic |
— |
| RS750641928 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750642580 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS750642581 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS750642821 |
ARL13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 8, Joubert syndrome 8 |
| RS750643216 |
CARD10
|
Health Risk |
risk factor |
Primary open angle glaucoma, Primary open angle glaucoma |
| RS750644251 |
TCTN3
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome 18, Orofacial-digital syndrome IV |
| RS750644305 |
TCF3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750645480 |
GNS
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-D |
| RS750646335 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750646887 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS750647348 |
TNNC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1Z, Hypertrophic cardiomyopathy 13 |
| RS750647872 |
MYO7A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 1B, Autosomal dominant nonsyndromic hearing loss 11 |
| RS750648216 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, FG syndrome |
| RS750649191 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750649426 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS750649530 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS750649974 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS750650349 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS750650768 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |