| RS750775588 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750777196 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750777752 |
SPRED1
|
Health Risk |
Pathogenic |
Legius syndrome, Noonan syndrome and Noonan-related syndrome |
| RS750777791 |
GBA1
|
Health Risk |
Likely pathogenic |
Gaucher disease, Gaucher disease |
| RS750777955 |
MPZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate D, Roussy-Lévy syndrome |
| RS750777960 |
VAC14
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750778014 |
KCNJ11
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Diabetes mellitus |
| RS750778630 |
VSX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated microphthalmia 2, Microphthalmia |
| RS750779804 |
SMPD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Niemann-Pick disease, type A |
| RS750780241 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS750780415 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS750780742 |
ASS1
|
Health Risk |
Likely pathogenic |
Citrullinemia type I, Citrullinemia type I |
| RS750781027 |
INPP5K
|
Health Risk |
Pathogenic |
Congenital muscular dystrophy with cataracts and intellectual disability, Congenital muscular dystrophy with cataracts and intellectual disability |
| RS750781063 |
TBCE
|
Health Risk |
Pathogenic |
Encephalopathy, progressive |
| RS750781606 |
CYP7B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia 5A |
| RS750782115 |
NCF2
|
Health Risk |
Pathogenic |
Granulomatous disease, chronic |
| RS750782462 |
OBSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
3M syndrome 2, 3M syndrome 2 |
| RS750782778 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS750783717 |
AP4M1
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 50, Hereditary spastic paraplegia 50 |
| RS750784794 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS750784979 |
LRP5
|
Health Risk |
Likely pathogenic |
— |
| RS750785243 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS750785483 |
DNAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Kartagener syndrome |
| RS750785552 |
TRMT1
|
Health Risk |
Likely pathogenic |
Intellectual developmental disorder, autosomal recessive 68 |
| RS750785582 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750787383 |
NFAT5
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, Immunodeficiency |
| RS750788947 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 4, Fibromatosis |
| RS750788949 |
ATP6V0A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Wrinkly skin syndrome, Cutis laxa with osteodystrophy |
| RS750789180 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
USH2A-related disorder, USH2A-related disorder |
| RS750789505 |
SPINK5
|
Health Risk |
Pathogenic |
Ichthyosis linearis circumflexa, Netherton syndrome |
| RS750791263 |
LRP5
|
Health Risk |
Likely pathogenic |
6 conditions, 6 conditions |
| RS750791932 |
PEX7
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 9B, Rhizomelic chondrodysplasia punctata |
| RS750792245 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS750792793 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS750793712 |
GNPTAB
|
Health Risk |
Likely pathogenic |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS750794400 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS750794851 |
ZAP70
|
Health Risk |
Pathogenic |
Combined immunodeficiency due to ZAP70 deficiency, Combined immunodeficiency due to ZAP70 deficiency |
| RS750796059 |
ACSF3
|
Health Risk |
Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS750796277 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750796687 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS750797779 |
SYNE4
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 76 |
| RS750797892 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 1, Inborn genetic diseases |
| RS750797985 |
CTSA
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined deficiency of sialidase AND beta galactosidase, Combined deficiency of sialidase AND beta galactosidase |
| RS750798165 |
PKD1
|
Health Risk |
Pathogenic |
Autosomal dominant polycystic kidney disease, PKD1-Biallelic Autosomal Recessive Polycystic Kidney Disease |
| RS750799705 |
TSFM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3, Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3 |
| RS750799861 |
EYS
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 25, Retinitis pigmentosa 25 |
| RS750800690 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS750801758 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1KK |
| RS750801787 |
RFX7
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal dominant 71 |
| RS750801808 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS750803038 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750803248 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Usher syndrome type 1D |
| RS750803388 |
GLDN
|
Health Risk |
Pathogenic/Likely pathogenic |
Fetal akinesia deformation sequence 1, Arthrogryposis multiplex congenita |
| RS750803516 |
GLRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperekplexia 2, Hyperekplexia 2 |
| RS750804063 |
ANO5
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS750804948 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS750805163 |
CDH3
|
Health Risk |
Conflicting classifications of pathogenicity |
EEM syndrome, EEM syndrome |
| RS750806023 |
CNGA3
|
Health Risk |
Pathogenic |
— |
| RS750806089 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750806151 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS750806202 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS750806272 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS750807406 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS750807433 |
SAMHD1
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 5, Chilblain lupus 2 |
| RS750809033 |
ASXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750809787 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS750811263 |
UNC13D
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis |
| RS750811871 |
KCTD7
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Progressive myoclonic epilepsy type 3 |
| RS750812086 |
HDAC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750812195 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS750814219 |
COL4A6
|
Health Risk |
Conflicting classifications of pathogenicity |
COL4A6-related disorder, Hearing loss |
| RS750815004 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia |
| RS750815208 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS750815238 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic Pulmonary Fibrosis, Dyskeratosis congenita |
| RS750815297 |
PLCE1
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 3 |
| RS750815369 |
OTULIN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750815560 |
RPGRIP1
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 13, Leber congenital amaurosis 6 |
| RS750815592 |
IRF6
|
Health Risk |
Conflicting classifications of pathogenicity |
Popliteal pterygium syndrome, Van der Woude syndrome |
| RS750815710 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS750816527 |
KLHL7
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS750817164 |
HPGD
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic osteoarthropathy, primary |
| RS750817344 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750817485 |
POP1
|
Health Risk |
Pathogenic |
— |
| RS750818039 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia |
| RS750819290 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS750819521 |
PHYH
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750819571 |
CYB5R3
|
Health Risk |
Likely pathogenic |
Deficiency of cytochrome-b5 reductase, Deficiency of cytochrome-b5 reductase |
| RS750820522 |
ANK1
|
Health Risk |
Pathogenic |
Hereditary spherocytosis type 1, Hereditary spherocytosis type 1 |
| RS750821412 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 9, Atypical hemolytic-uremic syndrome with C3 anomaly |
| RS750822014 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS750822703 |
SMARCB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750823043 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS750823506 |
PSTPIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyogenic arthritis-pyoderma gangrenosum-acne syndrome, Autoinflammatory syndrome |
| RS750824195 |
MTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylcobalamin deficiency type cblG, Methylcobalamin deficiency type cblG |
| RS750824848 |
MAD1L1
|
Health Risk |
Pathogenic |
Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition, Mosaic variegated aneuploidy syndrome 7 with inflammation and tumor predisposition |
| RS750825184 |
NFKB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750825686 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS750826324 |
NLGN4X
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750826355 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS750827325 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |