| RS750888081 |
SEC23B
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital dyserythropoietic anemia, type II |
| RS750889657 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS750889767 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750889782 |
GUCY2D
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 1, Leber congenital amaurosis |
| RS750890263 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS750890699 |
GATA2
|
Health Risk |
Pathogenic |
Deafness-lymphedema-leukemia syndrome, Monocytopenia with susceptibility to infections |
| RS750891085 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, ATP7B-related disorder |
| RS750894109 |
TYR
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 1A, Oculocutaneous albinism type 1A |
| RS750894392 |
MFRP
|
Health Risk |
Pathogenic |
Isolated microphthalmia 5, Isolated microphthalmia 5 |
| RS750894632 |
PLCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 3 |
| RS750895925 |
CDHR1
|
Health Risk |
Pathogenic/Likely pathogenic |
CDHR1-related disorder, CDHR1-related disorder |
| RS750896617 |
MOCOS
|
Health Risk |
Pathogenic/Likely pathogenic |
Xanthinuria type II, Autism spectrum disorder |
| RS750896639 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Basal ganglia calcification, idiopathic |
| RS750897443 |
TMEM231
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel syndrome, type 11 |
| RS750897569 |
PIGB
|
Health Risk |
Pathogenic |
— |
| RS750898335 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Junctional epidermolysis bullosa with pyloric atresia |
| RS750898743 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750899715 |
ACAD9
|
Health Risk |
Conflicting classifications of pathogenicity |
Acyl-CoA dehydrogenase 9 deficiency, Acyl-CoA dehydrogenase 9 deficiency |
| RS750899949 |
EFHC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750900506 |
LDLR
|
Health Risk |
Likely pathogenic |
Familial hypercholesterolemia, Familial hypercholesterolemia |
| RS750900568 |
CUL7
|
Health Risk |
Conflicting classifications of pathogenicity |
3M syndrome 1, 3M syndrome 1 |
| RS750900690 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy, Nemaline myopathy 2 |
| RS750901301 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, Severe myoclonic epilepsy in infancy |
| RS750901478 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Renal tubulopathies |
| RS750902549 |
ACBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750902578 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS750903219 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1KK, Dilated cardiomyopathy 1KK |
| RS750903875 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750904267 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive retinitis pigmentosa, Retinitis pigmentosa 25 |
| RS750904332 |
MEN1
|
Health Risk |
Pathogenic |
Multiple endocrine neoplasia, type 1 |
| RS750904635 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS750905566 |
MYO7A
|
Health Risk |
Pathogenic |
— |
| RS750905761 |
THRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Thyroid hormone resistance, generalized |
| RS750906253 |
GLIS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 7, Nephronophthisis |
| RS750906488 |
BEST1;FTH1
|
Health Risk |
Likely pathogenic |
Autosomal recessive bestrophinopathy, Autosomal recessive bestrophinopathy |
| RS750907088 |
WNK1
|
Health Risk |
Pathogenic |
Neuropathy, hereditary sensory and autonomic |
| RS750907780 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome and Noonan-related syndrome, RASopathy |
| RS750908017 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS750908377 |
TECPR2
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 49, Hereditary spastic paraplegia |
| RS750908839 |
LETM1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750909242 |
HPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome 1, Hermansky-Pudlak syndrome 1 |
| RS750911197 |
VAMP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Myasthenic syndrome |
| RS750911335 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, Autosomal dominant nonsyndromic hearing loss 17 |
| RS750911924 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Magenis syndrome, RAI1-related disorder |
| RS750912244 |
KIF11
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750912363 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS750913623 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS750915834 |
SLC19A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Megaloblastic anemia, thiamine-responsive |
| RS750915959 |
EXO1
|
Health Risk |
Likely pathogenic |
— |
| RS750916198 |
MCM3AP
|
Health Risk |
Pathogenic |
— |
| RS750916721 |
DNMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory neuropathy-deafness-dementia syndrome, Hereditary sensory neuropathy-deafness-dementia syndrome |
| RS750917538 |
RPGRIP1L
|
Health Risk |
Likely pathogenic |
Joubert syndrome 7, Joubert syndrome |
| RS750917672 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Dilated cardiomyopathy 3B |
| RS750920467 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750921440 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 11 |
| RS750922282 |
ZBTB18
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 22 |
| RS750924240 |
WDPCP
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Heart defect - tongue hamartoma - polysyndactyly syndrome |
| RS75092434 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCA4-related disorder, ABCA4-related disorder |
| RS750926172 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS750927507 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750928198 |
CTSA
|
Health Risk |
Pathogenic |
Combined deficiency of sialidase AND beta galactosidase, Combined deficiency of sialidase AND beta galactosidase |
| RS750930283 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Blepharophimosis - intellectual disability syndrome |
| RS750930293 |
SLC4A1
|
Health Risk |
Pathogenic/Likely pathogenic |
11 conditions, 11 conditions |
| RS750930363 |
RPGRIP1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS75093097 |
CENPF
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750931603 |
NR2E3
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS750931702 |
PROC
|
Health Risk |
Likely pathogenic |
— |
| RS750932643 |
KRT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Pachyonychia congenita 4, Pachyonychia congenita 4 |
| RS750932668 |
AGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS750934083 |
MAP2K1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome and Noonan-related syndrome, RASopathy |
| RS750935331 |
CLN5
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 5, Neuronal ceroid lipofuscinosis |
| RS750935580 |
FBXO38
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal hereditary motor neuropathy type 2, Distal hereditary motor neuropathy type 2 |
| RS750936389 |
ZEB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mowat-Wilson syndrome, Inborn genetic diseases |
| RS750936617 |
DEPDC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial focal epilepsy with variable foci, Inborn genetic diseases |
| RS750937093 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1 |
| RS750937323 |
CLN6
|
Health Risk |
Conflicting classifications of pathogenicity |
Ceroid lipofuscinosis, neuronal |
| RS750937792 |
MYL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 10, Cardiomyopathy |
| RS750937838 |
MCPH1
|
Health Risk |
Pathogenic |
— |
| RS750937874 |
G6PC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Inborn genetic diseases |
| RS750938556 |
AIP
|
Health Risk |
Pathogenic |
— |
| RS750938678 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS750939022 |
EIF2AK3
|
Health Risk |
Likely pathogenic |
Wolcott-Rallison dysplasia, Wolcott-Rallison dysplasia |
| RS750939090 |
PLA2G6
|
Health Risk |
Likely pathogenic |
Infantile neuroaxonal dystrophy, Autosomal recessive Parkinson disease 14 |
| RS750939401 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS750939831 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS750940208 |
FGD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aarskog syndrome, Aarskog syndrome |
| RS750941135 |
ACADS
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of butyryl-CoA dehydrogenase, Deficiency of butyryl-CoA dehydrogenase |
| RS750941179 |
COL4A5
|
Health Risk |
Likely pathogenic |
X-linked Alport syndrome, COL4A5-related disorder |
| RS750941501 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS750942168 |
CHAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial infantile myasthenia, Familial infantile myasthenia |
| RS750943685 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Migraine, familial hemiplegic |
| RS750943723 |
LAMTOR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary immunodeficiency syndrome due to p14 deficiency, Primary immunodeficiency syndrome due to p14 deficiency |
| RS750944055 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCB11-related disorder, ABCB11-related disorder |
| RS750944174 |
GNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-D |
| RS750944944 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 35, Cataract 35 |
| RS750945230 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS750946437 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS750946801 |
LARP7
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephalic primordial dwarfism, Alazami type |
| RS750947314 |
PABPC1L
|
Health Risk |
Pathogenic |
Female infertility due to zona pellucida defect, Female infertility due to zona pellucida defect |
| RS750947605 |
ARSB
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |