| RS750722169 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS750722358 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 5, Cranioectodermal dysplasia 4 |
| RS750723025 |
GANAB
|
Health Risk |
Pathogenic |
Autosomal dominant polycystic kidney disease, Autosomal dominant polycystic kidney disease |
| RS750723281 |
OBSCN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750723746 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750724065 |
RPE65
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 2, Retinitis pigmentosa 20 |
| RS750724439 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS750724544 |
TMC1
|
Health Risk |
Pathogenic |
— |
| RS750724648 |
SKIC2
|
Health Risk |
Pathogenic |
Trichohepatoenteric syndrome 2, Trichohepatoenteric syndrome 2 |
| RS750724856 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS750725128 |
LCA5
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 5, Leber congenital amaurosis 5 |
| RS75072667 |
PEX19
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder 12A (Zellweger), Peroxisome biogenesis disorder 12A (Zellweger) |
| RS750727201 |
HEXA
|
Health Risk |
Likely pathogenic |
Tay-Sachs disease, Inborn genetic diseases |
| RS750728042 |
HLCS
|
Health Risk |
Likely pathogenic |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS750728463 |
RAI1
|
Health Risk |
Pathogenic/Likely pathogenic |
Smith-Magenis syndrome, RAI1-related disorder |
| RS750728720 |
NPHP3
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS750729151 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750730042 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS750730828 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS750731609 |
AIMP1
|
Health Risk |
Pathogenic |
Hypomyelinating leukodystrophy 3, AIMP1-related disorder |
| RS750731624 |
LAMA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS750732115 |
SACS
|
Health Risk |
Pathogenic/Likely pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS750732485 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS750732565 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS750734000 |
CTBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hypotonia |
| RS750735308 |
GATA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hypoparathyroidism |
| RS750735794 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS750736741 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Inborn genetic diseases |
| RS750737346 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS750738167 |
ADGRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750739641 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS750739758 |
HSD3B7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750739947 |
NPC1
|
Health Risk |
Likely pathogenic |
Niemann-Pick disease, type C1 |
| RS750740148 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Multicystic kidney dysplasia, Rubinstein-Taybi syndrome due to CREBBP mutations |
| RS750740193 |
SAG
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 96, Retinitis pigmentosa 47 |
| RS750740230 |
RETREG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS750740421 |
KIAA0753
|
Health Risk |
Likely pathogenic |
Joubert syndrome 38, Joubert syndrome 38 |
| RS750740765 |
NR2E3
|
Health Risk |
Pathogenic |
Cone-rod dystrophy, Enhanced S-cone syndrome |
| RS750740789 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS750741137 |
FAH
|
Health Risk |
Pathogenic |
Tyrosinemia type I, Tyrosinemia type I |
| RS750741214 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS750741772 |
NAGLU
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2V, Mucopolysaccharidosis |
| RS750743110 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750743855 |
TGM6
|
Health Risk |
Likely pathogenic |
Spinocerebellar ataxia type 35, Spinocerebellar ataxia type 35 |
| RS750744696 |
TRIOBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 28, Autosomal recessive nonsyndromic hearing loss 28 |
| RS750744790 |
PROS1
|
Health Risk |
Likely pathogenic |
Thrombophilia due to protein S deficiency, autosomal dominant |
| RS750744914 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS750746034 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750746661 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS750747122 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiac arrhythmia |
| RS750747932 |
SLC45A2
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 4, Oculocutaneous albinism type 4 |
| RS750748531 |
LOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS750748658 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS750748828 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS750748842 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS750749323 |
MTTP
|
Health Risk |
Conflicting classifications of pathogenicity |
Abetalipoproteinaemia, Abetalipoproteinaemia |
| RS750750518 |
DNAI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750751739 |
ASAH1
|
Health Risk |
Likely pathogenic |
— |
| RS750752068 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750752838 |
MTHFR
|
Health Risk |
Likely pathogenic |
Homocystinuria due to methylene tetrahydrofolate reductase deficiency, Homocystinuria due to methylene tetrahydrofolate reductase deficiency |
| RS750753011 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750754640 |
NF1
|
Health Risk |
Pathogenic |
Neurofibromatosis, type 1 |
| RS750754763 |
KMT2D
|
Health Risk |
Pathogenic |
Kabuki syndrome 1, Kabuki syndrome 1 |
| RS750755532 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750755566 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS750755676 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS750755822 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS750756212 |
MPZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, type I |
| RS750756697 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS750756707 |
ITGA7
|
Health Risk |
Pathogenic |
Congenital muscular dystrophy due to integrin alpha-7 deficiency, Congenital muscular dystrophy due to integrin alpha-7 deficiency |
| RS750757143 |
KIAA1549
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS75075748 |
RET
|
Health Risk |
risk factor |
Hirschsprung disease, susceptibility to |
| RS750758181 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS75076115 |
AGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease type III, Inborn genetic diseases |
| RS750761966 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Myopathy |
| RS750762528 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
SETBP1-related disorder, Inborn genetic diseases |
| RS750763255 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS75076352 |
RET
|
Health Risk |
Pathogenic |
Pheochromocytoma, Multiple endocrine neoplasia type 2A |
| RS750763722 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750764003 |
CHKB
|
Health Risk |
Pathogenic |
Megaconial type congenital muscular dystrophy, CHKB-related disorder |
| RS750764149 |
PCNT
|
Health Risk |
Likely pathogenic |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS750764323 |
AIRE
|
Health Risk |
Likely pathogenic |
Polyglandular autoimmune syndrome, type 1 |
| RS750764507 |
WDFY3
|
Health Risk |
Likely pathogenic |
Microcephaly 18, primary |
| RS750764548 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Inborn genetic diseases |
| RS750765107 |
TG
|
Health Risk |
Conflicting classifications of pathogenicity |
Iodotyrosyl coupling defect, Iodotyrosyl coupling defect |
| RS750765152 |
TRIM63
|
Health Risk |
Pathogenic |
Idiopathic cardiomyopathy, Idiopathic cardiomyopathy |
| RS750765175 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS750766653 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS750767033 |
NDUFV1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS750767043 |
GGCX
|
Health Risk |
Pathogenic |
GGCX - Related Disorders, GGCX - Related Disorders |
| RS750767967 |
ADGRE2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750769299 |
FOXE3
|
Health Risk |
Likely pathogenic |
— |
| RS750771818 |
NPRL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, familial focal |
| RS750773513 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750773606 |
FLVCR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fowler syndrome, FLVCR2-related disorder |
| RS750773622 |
SGCB
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2E, Autosomal recessive limb-girdle muscular dystrophy type 2E |
| RS750773640 |
MRPS34
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation deficiency 32, Combined oxidative phosphorylation deficiency 32 |
| RS750774484 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS750775106 |
AAAS
|
Health Risk |
Pathogenic |
— |
| RS750775126 |
KDM5B
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, autosomal recessive 65 |