| RS750827513 |
COQ9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750828226 |
PRICKLE2
|
Health Risk |
Likely pathogenic |
See cases, See cases |
| RS750828431 |
SNF8
|
Health Risk |
Pathogenic |
SNF8-associated disease, Developmental and epileptic encephalopathy 115 |
| RS750829010 |
ABCB4
|
Health Risk |
Likely pathogenic |
Progressive familial intrahepatic cholestasis type 3, Progressive familial intrahepatic cholestasis type 3 |
| RS750830935 |
NDUFA6
|
Health Risk |
Pathogenic |
Mitochondrial disease, Mitochondrial complex I deficiency |
| RS750831299 |
NDUFV1
|
Health Risk |
Pathogenic/Likely pathogenic |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS750832804 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750833108 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS750833160 |
KIAA0586
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 23, Short-rib thoracic dysplasia 14 with polydactyly |
| RS750833867 |
IL37
|
Health Risk |
Pathogenic |
Inflammatory bowel disease, Inflammatory bowel disease |
| RS750834241 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pendred syndrome, Pendred syndrome |
| RS750835120 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS750835733 |
CACNA1C
|
Health Risk |
Pathogenic |
Long QT syndrome, Long QT syndrome 8 |
| RS750836033 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1S, Hypertrophic cardiomyopathy |
| RS750836049 |
SLC2A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi-Bickel syndrome, Fanconi-Bickel syndrome |
| RS750836133 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome |
| RS750836266 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750836360 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Hypercholesterolemia |
| RS750837082 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Congenital contractural arachnodactyly |
| RS750838060 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hearing impairment |
| RS750838511 |
MTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Disorders of Intracellular Cobalamin Metabolism, Methylcobalamin deficiency type cblG |
| RS750838853 |
FH
|
Health Risk |
Pathogenic |
— |
| RS750839091 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS750839601 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS750840208 |
EYS
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 25, Retinal dystrophy |
| RS750840234 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, B lymphoblastic leukemia lymphoma with t(12 |
| RS750840362 |
PCCA
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS75084078 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750842366 |
ESCO2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Roberts-SC phocomelia syndrome |
| RS750842859 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS750843149 |
PKD1
|
Health Risk |
Pathogenic |
PKD1-related disorder, PKD1-related disorder |
| RS750843326 |
FANCG
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group G |
| RS750844090 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS750845399 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to CREBBP mutations, Menke-Hennekam syndrome 1 |
| RS750845916 |
ARSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS750846632 |
CLTC
|
Health Risk |
Likely pathogenic |
— |
| RS750848278 |
PAX6
|
Health Risk |
Pathogenic/Likely pathogenic |
Aniridia 1, Aniridia 1 |
| RS750849080 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS750849285 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
MEN1-related disorder, Multiple endocrine neoplasia |
| RS750849536 |
SLC7A9
|
Health Risk |
Likely pathogenic |
Cystinuria, Cystinuria |
| RS750849844 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS750849852 |
RAG2
|
Health Risk |
Pathogenic |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS750850720 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS750850786 |
ATL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS750850949 |
CFI
|
Health Risk |
Likely pathogenic |
Atypical hemolytic-uremic syndrome with I factor anomaly, Atypical hemolytic-uremic syndrome with I factor anomaly |
| RS750851792 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750852645 |
CEBPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute myeloid leukemia, Inborn genetic diseases |
| RS750852737 |
ADCY3
|
Health Risk |
Uncertain significance; risk factor |
BODY MASS INDEX QUANTITATIVE TRAIT LOCUS 19, ADCY3-related disorder |
| RS750853380 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy 94 |
| RS750853882 |
AP3D1
|
Health Risk |
Conflicting classifications of pathogenicity |
AP3D1-related disorder, AP3D1-related disorder |
| RS750854950 |
CCIN
|
Health Risk |
Pathogenic |
Spermatogenic failure 91, Spermatogenic failure 91 |
| RS750855113 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750855317 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS750856173 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS750857784 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750857876 |
PYGM
|
Health Risk |
Pathogenic |
Glycogen storage disease, type V |
| RS750858075 |
OR2W3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750860161 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750860338 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750860886 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS75086141 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperkalemic periodic paralysis, 7 conditions |
| RS750862009 |
ABCA3
|
Health Risk |
Pathogenic/Likely pathogenic |
Interstitial lung disease due to ABCA3 deficiency, Hereditary pulmonary alveolar proteinosis |
| RS750862933 |
EPHB4
|
Health Risk |
Pathogenic |
— |
| RS75086406 |
FH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary leiomyomatosis and renal cell cancer, Hereditary cancer-predisposing syndrome |
| RS750864641 |
STRA6
|
Health Risk |
Likely pathogenic |
Microphthalmia, Microphthalmia |
| RS750864821 |
NIPBL
|
Health Risk |
Likely pathogenic |
Cornelia de Lange syndrome 1, Cornelia de Lange syndrome 1 |
| RS750865703 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Pheochromocytoma/paraganglioma syndrome 5, Mitochondrial complex II deficiency |
| RS750866397 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750866614 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS750867074 |
MYO15A
|
Health Risk |
Pathogenic |
— |
| RS750868020 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, Ehlers-Danlos syndrome |
| RS750869245 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750869272 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS750869685 |
LAMB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cobblestone lissencephaly without muscular or ocular involvement |
| RS750870502 |
TNNI3
|
Health Risk |
Likely pathogenic |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS750870933 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750870974 |
TMEM127
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Pheochromocytoma |
| RS750871999 |
FANCL
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Inborn genetic diseases |
| RS750872620 |
KCNQ5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750872744 |
CRYGC
|
Health Risk |
Likely pathogenic |
— |
| RS750872878 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS750873571 |
SERPING1
|
Health Risk |
Pathogenic |
Hereditary angioedema with C1Inh deficiency, Hereditary angioedema with C1Inh deficiency |
| RS750874617 |
POLR3A
|
Health Risk |
Pathogenic/Likely pathogenic |
Leukodystrophy, hypomyelinating |
| RS750876165 |
MSH3
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750876420 |
GNPTAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudo-Hurler polydystrophy, Mucolipidosis type II |
| RS750877978 |
CYP7A1
|
Health Risk |
Pathogenic |
— |
| RS750880244 |
FAM20A
|
Health Risk |
Pathogenic |
Amelogenesis imperfecta type 1G, Amelogenesis imperfecta type 1G |
| RS750880909 |
CDH23
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Nonsyndromic genetic hearing loss |
| RS750881309 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750881596 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Acute myeloid leukemia |
| RS750881912 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal myopathy with posterior leg and anterior hand involvement, Myofibrillar myopathy 5 |
| RS750882072 |
HOXA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bilateral microtia-deafness-cleft palate syndrome, Inborn genetic diseases |
| RS750882937 |
SLC26A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple epiphyseal dysplasia type 4, Diastrophic dysplasia |
| RS750883399 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS750883857 |
SLC35A3
|
Health Risk |
Likely pathogenic |
Autism spectrum disorder - epilepsy - arthrogryposis syndrome, Autism spectrum disorder - epilepsy - arthrogryposis syndrome |
| RS750884499 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS750885553 |
SPART
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750886219 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 14, Primary dilated cardiomyopathy |
| RS750886274 |
G6PC1
|
Health Risk |
Likely pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS750887042 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, Inborn genetic diseases |