COQ9 Chromosome 16

Coenzyme Q9
31 variants 31 Health Risk

Upload your DNA to see your personal genotypes for variants in COQ9.

What This Gene Does
This locus represents a mitochondrial ubiquinone biosynthesis gene. The encoded protein is likely necessary for biosynthesis of coenzyme Q10, as mutations at this locus have been associated with autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency.[provided by RefSeq, Sep 2010]
Associated Conditions (5)
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
COQ9-related disorder
Inborn genetic diseases
Leigh syndrome
Lung cancer
Key Variants
RS11547480
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, COQ9-related disorder, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
RS1189201208
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
RS1276732246
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS181356497
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
RS201097286
Conflicting classifications of pathogenicity
Health Risk
RS201238241
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
RS536567108
Conflicting classifications of pathogenicity
Health Risk
RS536847466
Conflicting classifications of pathogenicity
Health Risk
RS547254482
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
RS578214371
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
RS750827513
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS757251412
Conflicting classifications of pathogenicity
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Inborn genetic diseases, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
Health Risk
All Variants (31)
RSID Category Clinical Significance Conditions
RS11547480 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, COQ9-related disorder, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS1189201208 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS1276732246 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS181356497 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS201097286 Health Risk Conflicting classifications of pathogenicity
RS201238241 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS536567108 Health Risk Conflicting classifications of pathogenicity
RS536847466 Health Risk Conflicting classifications of pathogenicity
RS547254482 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS578214371 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS750827513 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS757251412 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Inborn genetic diseases, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS757816546 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS758943543 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Inborn genetic diseases, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS76508383 Health Risk Conflicting classifications of pathogenicity Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, COQ9-related disorder, Leigh syndrome
RS747898678 Health Risk Likely pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS752219939 Health Risk Likely pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Lung cancer, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS1160280040 Health Risk Pathogenic Inborn genetic diseases, Inborn genetic diseases
RS1491334480 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS2030153941 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS2146591222 Health Risk Pathogenic
RS2543566429 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS2543573817 Health Risk Pathogenic
RS267606751 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS368777580 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS746155423 Health Risk Pathogenic
RS751556970 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS755558659 Health Risk Pathogenic
RS759658215 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
RS770175074 Health Risk Pathogenic
RS786205897 Health Risk Pathogenic Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
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