| RS750651204 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS750651809 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS750653037 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome |
| RS750653834 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS750655311 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1A, Dilated cardiomyopathy 1KK |
| RS750655470 |
TINF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Dyskeratosis congenita |
| RS750655720 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS750656470 |
SLC4A11
|
Health Risk |
Likely pathogenic |
Corneal dystrophy, Fuchs endothelial |
| RS750658321 |
ODAD3
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 30, Primary ciliary dyskinesia 30 |
| RS750658890 |
SUN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy, Emery-Dreifuss muscular dystrophy |
| RS750659716 |
ACSL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS750660824 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750661309 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750662250 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoinflammatory syndrome, Chédiak-Higashi syndrome |
| RS750663070 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750663117 |
ATM
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS750663981 |
SPG11
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia |
| RS750664040 |
PINK1
|
Health Risk |
Pathogenic |
Autosomal recessive early-onset Parkinson disease 6, Autosomal recessive early-onset Parkinson disease 6 |
| RS750664148 |
MYC
|
Health Risk |
Pathogenic |
Acute myeloid leukemia, Acute myeloid leukemia |
| RS750664256 |
PLOD2
|
Health Risk |
Pathogenic |
— |
| RS750664956 |
ASPM
|
Health Risk |
Pathogenic |
— |
| RS750665609 |
BBS10
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS750665866 |
PLEKHG5
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease recessive intermediate C, Neuronopathy |
| RS750665937 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Congenital myopathy |
| RS750666025 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS750666346 |
PDE4D
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrodysostosis 2 with or without hormone resistance, Inborn genetic diseases |
| RS750667529 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS750667928 |
IL12RB1
|
Health Risk |
Likely pathogenic |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency |
| RS750668627 |
GAA
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type II |
| RS750669148 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS750669368 |
RNASET2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS750669994 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS750670743 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750671399 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS750671777 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS750672211 |
SIX5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750675692 |
ACADVL
|
Health Risk |
Pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS750676893 |
SPATA7
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 3, Retinitis pigmentosa |
| RS750677189 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS75067824 |
DNAH7
|
Health Risk |
Conflicting classifications of pathogenicity |
DNAH7-related disorder, DNAH7-related disorder |
| RS750678272 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Dilated cardiomyopathy 1G |
| RS750680286 |
SPTLC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 1, Neuropathy |
| RS75068032 |
NOTCH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebral arteriopathy, autosomal dominant |
| RS750681131 |
FAM149B1
|
Health Risk |
Pathogenic |
Joubert syndrome 36, Clear cell carcinoma of kidney |
| RS750681891 |
ZNF142
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder with impaired speech and hyperkinetic movements, Neurodevelopmental disorder with impaired speech and hyperkinetic movements |
| RS750682546 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS750683352 |
ABCC2
|
Health Risk |
Pathogenic |
— |
| RS750684515 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Sotos syndrome |
| RS750685055 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS750685598 |
HPS3
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome, HPS3-related disorder |
| RS750685646 |
B3GAT3
|
Health Risk |
Pathogenic/Likely pathogenic |
Larsen-like syndrome, B3GAT3 type |
| RS750686083 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal myopathy with posterior leg and anterior hand involvement, Myofibrillar myopathy 5 |
| RS750686148 |
SPRED1
|
Health Risk |
Conflicting classifications of pathogenicity |
Legius syndrome, Legius syndrome |
| RS750686734 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS750688292 |
FRMD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750689059 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS750689118 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Asphyxiating thoracic dystrophy 3 |
| RS750690310 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750691939 |
BBS7
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 7, Bardet-Biedl syndrome |
| RS750692650 |
WDFY3
|
Health Risk |
Pathogenic |
— |
| RS750693109 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Cohen syndrome |
| RS750693417 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS750693623 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Inborn genetic diseases |
| RS750694928 |
POLR3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism |
| RS750695074 |
MECOM
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750695182 |
G6PC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency, Autosomal recessive severe congenital neutropenia due to G6PC3 deficiency |
| RS750695521 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Cardiovascular phenotype |
| RS750696284 |
CSPP1
|
Health Risk |
Pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS750696928 |
DRD4
|
Health Risk |
Likely pathogenic |
Hereditary attention deficit-hyperactivity disorder, Hereditary attention deficit-hyperactivity disorder |
| RS750697040 |
ALDH3A2
|
Health Risk |
Likely pathogenic |
Sjögren-Larsson syndrome, Sjögren-Larsson syndrome |
| RS750698432 |
POLRMT
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation deficiency 55, Combined oxidative phosphorylation deficiency 55 |
| RS750698494 |
LTBP4
|
Health Risk |
Likely pathogenic |
— |
| RS750699019 |
PYGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type VI |
| RS750699540 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750699545 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign familial hematuria, Benign familial hematuria |
| RS750699844 |
CTSK
|
Health Risk |
Pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS750700066 |
LAMC2
|
Health Risk |
Pathogenic |
— |
| RS750700691 |
C2CD3
|
Health Risk |
Pathogenic/Likely pathogenic |
Orofaciodigital syndrome type 14, Orofaciodigital syndrome type 14 |
| RS750701057 |
FOXP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Childhood apraxia of speech |
| RS750703971 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS750704702 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS750705900 |
AP3B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750707504 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750707642 |
TYMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750708103 |
PMM2
|
Health Risk |
Likely pathogenic |
PMM2-congenital disorder of glycosylation, PMM2-congenital disorder of glycosylation |
| RS750708201 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750710187 |
COQ2
|
Health Risk |
Pathogenic/Likely pathogenic |
Coenzyme Q10 deficiency, primary |
| RS750710267 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS75071027 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS750710315 |
SLC12A3
|
Health Risk |
Pathogenic |
Bartter syndrome, Familial hypokalemia-hypomagnesemia |
| RS750712213 |
FIG4
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Yunis-Varon syndrome |
| RS750714387 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS750715942 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS750717767 |
TBCD
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS750718366 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, Autosomal dominant nonsyndromic hearing loss 17 |
| RS750720912 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS750720946 |
SLC7A7
|
Health Risk |
Conflicting classifications of pathogenicity |
Lysinuric protein intolerance, Autoinflammatory syndrome |
| RS750720985 |
ACVRL1
|
Health Risk |
Pathogenic |
Telangiectasia, hereditary hemorrhagic |
| RS750721065 |
HRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Costello syndrome, Costello syndrome |
| RS750721291 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |