| RS750457185 |
DLL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndactyly, Spondylocostal dysostosis 1 |
| RS750457207 |
F7
|
Health Risk |
Pathogenic/Likely pathogenic |
Factor VII deficiency, Abnormal bleeding |
| RS750457269 |
KCND2
|
Health Risk |
Pathogenic/Likely pathogenic |
Early myoclonic encephalopathy, Inborn genetic diseases |
| RS750457525 |
SNORD118;TMEM107
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukoencephalopathy with calcifications and cysts, Meckel-Gruber syndrome |
| RS750459631 |
GABRG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Self-limited epilepsy with centrotemporal spikes, Febrile seizures |
| RS750459929 |
MAX
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pheochromocytoma and paraganglioma, Hereditary cancer-predisposing syndrome |
| RS750460626 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750460795 |
KIZ
|
Health Risk |
Likely pathogenic |
Lung cancer, Lung cancer |
| RS750461872 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS750462550 |
BBS4
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 4, Bardet-Biedl syndrome |
| RS750463562 |
KIF22
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750465793 |
NHLRC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Lafora disease, Myoclonic epilepsy of Lafora 2 |
| RS750466433 |
TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS750467268 |
GABBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS750468923 |
IL2RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency due to CD25 deficiency, Immunodeficiency due to CD25 deficiency |
| RS750470269 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS750470470 |
POT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS750470640 |
EDEM3
|
Health Risk |
Pathogenic |
— |
| RS750470654 |
G6PC1
|
Health Risk |
Pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, G6PC1-related disorder |
| RS750470900 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS750471097 |
COL6A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Bethlem myopathy 1A, Dystonia 27 |
| RS750471995 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS750472100 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS750472969 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, 14 conditions |
| RS750473075 |
IVD
|
Health Risk |
Conflicting classifications of pathogenicity |
Isovaleryl-CoA dehydrogenase deficiency, IVD-related disorder |
| RS750473230 |
CEP104
|
Health Risk |
Pathogenic/Likely pathogenic |
See cases, Joubert syndrome 25 |
| RS750473506 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic ataxia, Spastic ataxia |
| RS750475050 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly and chorioretinopathy 1, Inborn genetic diseases |
| RS750475071 |
MMUT
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency |
| RS750475467 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS750476171 |
LRP2
|
Health Risk |
Likely pathogenic |
— |
| RS750477816 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Inborn genetic diseases |
| RS750477821 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS750479923 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, Lymphatic malformation 6 |
| RS750479975 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS75048006 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Merosin deficient congenital muscular dystrophy |
| RS750481017 |
LHCGR
|
Health Risk |
Pathogenic |
Pseudohermaphroditism, Pseudohermaphroditism |
| RS750481489 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brittle cornea syndrome 1 |
| RS750481560 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750483952 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial meningioma |
| RS750484094 |
IL17RC
|
Health Risk |
Conflicting classifications of pathogenicity |
Candidiasis, familial |
| RS750484458 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS750484977 |
MCCC1
|
Health Risk |
Pathogenic |
3-methylcrotonyl-CoA carboxylase 1 deficiency, 3-methylcrotonyl-CoA carboxylase 1 deficiency |
| RS750486472 |
CARD11
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency due to CARD11 deficiency, BENTA disease |
| RS750486813 |
MOGS
|
Health Risk |
Pathogenic |
MOGS-congenital disorder of glycosylation, MOGS-congenital disorder of glycosylation |
| RS750488007 |
SZT2
|
Health Risk |
Pathogenic |
— |
| RS750489139 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750491874 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS750492389 |
AGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS750494502 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS750494564 |
BTD
|
Health Risk |
Conflicting classifications of pathogenicity |
Biotinidase deficiency, Biotinidase deficiency |
| RS750494795 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750495564 |
ACTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 11, Dilated cardiomyopathy 1R |
| RS750496742 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 3, Maturity-onset diabetes of the young |
| RS750496798 |
IDUA
|
Health Risk |
Likely pathogenic |
Hurler syndrome, Mucopolysaccharidosis type 1 |
| RS750501197 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS750501225 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS750501256 |
PCARE
|
Health Risk |
Pathogenic |
— |
| RS750502323 |
NEB
|
Health Risk |
Likely pathogenic |
Arthrogryposis multiplex congenita 6, Arthrogryposis multiplex congenita 6 |
| RS750502331 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS750502935 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750503329 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, 6 conditions |
| RS750503504 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS750504354 |
RAD21
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 4, Cornelia de Lange syndrome 4 |
| RS750505963 |
ASPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Spongy degeneration of central nervous system, Canavan Disease |
| RS750506474 |
BBS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 2, Retinal dystrophy |
| RS750508765 |
APC
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS750510834 |
SLC45A2
|
Health Risk |
Likely pathogenic |
— |
| RS750512029 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS750512162 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS750513275 |
QDPR
|
Health Risk |
Likely pathogenic |
— |
| RS750513286 |
DNAAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS750513716 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized juvenile polyposis/juvenile polyposis coli, Hereditary cancer-predisposing syndrome |
| RS750513879 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750514687 |
POLG
|
Health Risk |
Pathogenic |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS750515166 |
EPAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS750515748 |
DNMT3A
|
Health Risk |
Pathogenic |
Tatton-Brown-Rahman overgrowth syndrome, Tatton-Brown-Rahman overgrowth syndrome |
| RS750516202 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS750516275 |
SLC25A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy-hypotonia-lactic acidosis syndrome, Cardiomyopathy-hypotonia-lactic acidosis syndrome |
| RS750518671 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS750519430 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750520052 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS750520309 |
CUBN
|
Health Risk |
Likely pathogenic |
Imerslund-Grasbeck syndrome, Imerslund-Grasbeck syndrome type 1 |
| RS750520685 |
PTPN11
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Metachondromatosis |
| RS750521452 |
OTOG
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 18B, Autosomal recessive nonsyndromic hearing loss 18B |
| RS750521601 |
TTC8
|
Health Risk |
Likely pathogenic |
— |
| RS750521781 |
RFT1
|
Health Risk |
Conflicting classifications of pathogenicity |
RFT1-congenital disorder of glycosylation, RFT1-congenital disorder of glycosylation |
| RS750524069 |
CYP4V2
|
Health Risk |
Likely pathogenic |
— |
| RS750524447 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Abnormality of the nervous system |
| RS750524549 |
A2ML1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750525727 |
TRPC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis, TRPC6-related disorder |
| RS750526487 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750526659 |
IRF3
|
Health Risk |
Uncertain significance; risk factor |
Encephalopathy, acute |
| RS750526692 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Familial restrictive cardiomyopathy |
| RS750526802 |
TRAPPC9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750526845 |
LMX1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis, Nail-patella syndrome |
| RS750527536 |
TPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750528020 |
RSPH4A
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 11 |
| RS750528093 |
MSH6
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750528095 |
SKIC2
|
Health Risk |
Pathogenic |
— |