| RS751074844 |
SKIC2
|
Health Risk |
Pathogenic |
Trichohepatoenteric syndrome 2, Trichohepatoenteric syndrome 2 |
| RS751075073 |
MCMDC2
|
Health Risk |
Likely pathogenic |
Male infertility with azoospermia or oligozoospermia due to single gene mutation, Male infertility with azoospermia or oligozoospermia due to single gene mutation |
| RS751076276 |
SH2B3
|
Health Risk |
Likely pathogenic |
Primary myelofibrosis, Primary myelofibrosis |
| RS751076530 |
PEX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Heimler syndrome 1, Zellweger spectrum disorders |
| RS751076878 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS751078884 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS751079525 |
GALE
|
Health Risk |
Conflicting classifications of pathogenicity |
UDPglucose-4-epimerase deficiency, UDPglucose-4-epimerase deficiency |
| RS751079690 |
ALDH3A2
|
Health Risk |
Likely pathogenic |
Sjögren-Larsson syndrome, Sjögren-Larsson syndrome |
| RS751080704 |
MARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, Charcot-Marie-Tooth disease axonal type 2U |
| RS751080818 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS751081026 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS751081074 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Charcot-Marie-Tooth disease axonal type 2O |
| RS751082361 |
SIL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marinesco-Sjögren syndrome, Marinesco-Sjögren syndrome |
| RS751082926 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS751084282 |
PHKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXb, Glycogen storage disease IXb |
| RS751084365 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, Charcot-Marie-Tooth disease type 2 |
| RS751084512 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS751084584 |
GALT
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase, Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase |
| RS751085066 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS751086453 |
PIGO
|
Health Risk |
Pathogenic |
Hyperphosphatasia with intellectual disability syndrome 2, Hyperphosphatasia with intellectual disability syndrome 2 |
| RS751088292 |
TPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 2, Inborn genetic diseases |
| RS751088347 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS751090118 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS751090469 |
CPT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine palmitoyltransferase II deficiency, Inborn genetic diseases |
| RS751090809 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS751090951 |
PROS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia due to protein S deficiency, autosomal recessive |
| RS751092504 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS751093304 |
CDON
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly 11, Inborn genetic diseases |
| RS751093392 |
HLCS
|
Health Risk |
Likely pathogenic |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS751093906 |
SLC20A2
|
Health Risk |
Pathogenic |
Idiopathic basal ganglia calcification 1, Idiopathic basal ganglia calcification 1 |
| RS751094013 |
CHD8
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder, Intellectual developmental disorder with autism and macrocephaly |
| RS751094041 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751094147 |
AGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS751094298 |
PRKAG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital glycogen storage disease of heart, Cardiomyopathy |
| RS751095642 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS751096098 |
RPGRIP1
|
Health Risk |
Pathogenic |
Leber congenital amaurosis 6, Leber congenital amaurosis 6 |
| RS751097660 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751097758 |
GFPT1
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 12, Congenital myasthenic syndrome |
| RS751098333 |
CFTR
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystic fibrosis, Cystic fibrosis |
| RS751098874 |
PEX10
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, complementation group 7 |
| RS751099539 |
GFM2
|
Health Risk |
Likely pathogenic |
— |
| RS751101220 |
MIPEP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Lethal left ventricular non-compaction-seizures-hypotonia-cataract-developmental delay syndrome |
| RS751101419 |
SLC25A46
|
Health Risk |
Pathogenic |
Pontocerebellar hypoplasia, type 1E |
| RS751101495 |
GRHPR
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary hyperoxaluria, type II |
| RS751102649 |
CARMIL2
|
Health Risk |
Likely pathogenic |
— |
| RS751103088 |
SPAG1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia 28 |
| RS751103286 |
JAM2
|
Health Risk |
Pathogenic |
Basal ganglia calcification, idiopathic |
| RS751104396 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Abnormality of the musculature, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS751104940 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS751105293 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1B |
| RS751107938 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Osteogenesis imperfecta type I |
| RS751107971 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS751109501 |
ADAMTSL4
|
Health Risk |
Likely pathogenic |
— |
| RS751110498 |
SORL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751111524 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Usher syndrome type 2A |
| RS751111546 |
GABBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS751112173 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 9, Bardet-Biedl syndrome |
| RS751112302 |
AGL
|
Health Risk |
Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS751112452 |
WRN
|
Health Risk |
Pathogenic |
Werner syndrome, Werner syndrome |
| RS751112698 |
SLC12A3
|
Health Risk |
Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS751113129 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Hematuria |
| RS751113638 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS751115103 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebrooculofacioskeletal syndrome 1, Cockayne syndrome type 2 |
| RS751115639 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS751116452 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751116790 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Inborn genetic diseases |
| RS751117377 |
MPZL2
|
Health Risk |
Likely pathogenic |
— |
| RS751117590 |
KRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS751117857 |
USH2A
|
Health Risk |
Pathogenic |
— |
| RS751118731 |
VPS13B
|
Health Risk |
Pathogenic |
Cohen syndrome, Cohen syndrome |
| RS751118849 |
RANBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial acute necrotizing encephalopathy, Familial acute necrotizing encephalopathy |
| RS751119069 |
CEL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751120046 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS751120519 |
FAM161A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751120868 |
TSEN54
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontoneocerebellar hypoplasia, Pontoneocerebellar hypoplasia |
| RS751121559 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751122249 |
PRICKLE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy type 5, Progressive myoclonic epilepsy type 5 |
| RS751122263 |
ABRAXAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751122392 |
IFT43
|
Health Risk |
Likely pathogenic |
— |
| RS751122998 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS751123751 |
LZTR1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS751124572 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1A |
| RS751124745 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS751125011 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS751125855 |
ADAMTSL4
|
Health Risk |
Pathogenic |
— |
| RS751126274 |
UNG
|
Health Risk |
Pathogenic |
Hyper-IgM syndrome type 5, Hyper-IgM syndrome type 5 |
| RS751127087 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Cornelia de Lange syndrome 1 |
| RS751128167 |
CFAP418
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, CFAP418-related disorder |
| RS751128287 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Tuberous sclerosis syndrome |
| RS751128300 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS751129547 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS751130485 |
USH2A
|
Health Risk |
Pathogenic |
Usher syndrome type 2A, Retinal dystrophy |
| RS751131066 |
NONO
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability 34, Syndromic X-linked intellectual disability 34 |
| RS751132977 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Haddad syndrome, Hereditary cancer-predisposing syndrome |
| RS751133155 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751133336 |
MCCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Inborn genetic diseases |
| RS751134093 |
MPV17
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease, axonal |
| RS751134443 |
ARHGEF10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751136702 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Ehlers-Danlos syndrome |
| RS751137584 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Freeman-Sheldon syndrome, Distal arthrogryposis type 2B1 |