| RS751139032 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS751139506 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Charcot-Marie-Tooth disease axonal type 2C |
| RS751140324 |
LRPPRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751141 |
EPHX2
|
Health Risk |
risk factor |
Hypercholesterolemia, familial |
| RS751142345 |
WDR4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Microcephaly |
| RS751142446 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS751142825 |
SPAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia |
| RS751143580 |
AHNAK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751144068 |
IL2RB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751145286 |
KMT5B
|
Health Risk |
Pathogenic |
— |
| RS751145746 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751145927 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1A, Dystrophin deficiency |
| RS751146386 |
KDM6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 2, Kabuki syndrome 2 |
| RS751146607 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Rubinstein-Taybi syndrome |
| RS751147313 |
FLG
|
Health Risk |
Pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS751147419 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS751147622 |
ENPP1
|
Health Risk |
Likely pathogenic |
Arterial calcification, generalized |
| RS751147673 |
ADA
|
Health Risk |
Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS751147980 |
MITF
|
Health Risk |
Conflicting classifications of pathogenicity |
Waardenburg syndrome type 2A, Tietz syndrome |
| RS751148574 |
PEX5
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder 2B, Peroxisome biogenesis disorder 2A (Zellweger) |
| RS751148714 |
HLCS
|
Health Risk |
Likely pathogenic |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS751148760 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Idiopathic generalized epilepsy |
| RS751149105 |
CERKL
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 26, Retinitis pigmentosa |
| RS751149568 |
MME
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2T, Inborn genetic diseases |
| RS751149776 |
PRODH
|
Health Risk |
Conflicting classifications of pathogenicity |
Proline dehydrogenase deficiency, Schizophrenia 4 |
| RS751150295 |
CLCN7
|
Health Risk |
Pathogenic |
— |
| RS751150566 |
IFT81
|
Health Risk |
Likely pathogenic |
— |
| RS75115087 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Congenital bilateral aplasia of vas deferens from CFTR mutation |
| RS751151452 |
DNAH8
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS751153777 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 14 |
| RS751153838 |
PMS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS751154230 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Myhre syndrome |
| RS751155680 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751157497 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 5 |
| RS751157908 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
TTN-related disorder, Cardiovascular phenotype |
| RS751158831 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS751159722 |
MMADHC
|
Health Risk |
Pathogenic/Likely pathogenic |
Methylmalonic aciduria and homocystinuria type cblD, Methylmalonic aciduria and homocystinuria type cblD |
| RS751159969 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS751160202 |
MC4R
|
Health Risk |
Pathogenic |
Obesity, autosomal dominant |
| RS751161649 |
MPDZ
|
Health Risk |
Pathogenic/Likely pathogenic |
Hydrocephalus, nonsyndromic |
| RS751161742 |
PRF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, Aplastic anemia |
| RS751162519 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751162614 |
FOXC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS75116272 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS751163127 |
FAT1
|
Health Risk |
Likely pathogenic |
FAT1-related disorder, FAT1-related disorder |
| RS751163688 |
ACADM
|
Health Risk |
Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS751163782 |
RAB28
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone-rod dystrophy 18, Cone-rod dystrophy 18 |
| RS751165188 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS751165635 |
AHDC1
|
Health Risk |
Pathogenic |
— |
| RS75116612 |
ADCY10
|
Health Risk |
Conflicting classifications of pathogenicity |
ADCY10-related disorder, ADCY10-related disorder |
| RS751167632 |
FRAS1
|
Health Risk |
Pathogenic |
FRAS1-related disorder, FRAS1-related disorder |
| RS751168951 |
ATM
|
Health Risk |
Likely pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS751169467 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS751169823 |
TSFM
|
Health Risk |
Pathogenic/Likely pathogenic |
Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3, Fatal mitochondrial disease due to combined oxidative phosphorylation defect type 3 |
| RS751169871 |
FBN1
|
Health Risk |
Likely pathogenic |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS751170471 |
PLK4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751170564 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS751170778 |
STXBP1
|
Health Risk |
Pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS751172150 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Tuberous sclerosis 2 |
| RS751172449 |
C1QB
|
Health Risk |
Likely pathogenic |
C1Q deficiency 2, C1Q deficiency 2 |
| RS751172816 |
PCDH12
|
Health Risk |
Conflicting classifications of pathogenicity |
Diencephalic-mesencephalic junction dysplasia syndrome 1, Diencephalic-mesencephalic junction dysplasia syndrome 1 |
| RS751173584 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751173836 |
ACTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Platelet-type bleeding disorder 15, Platelet-type bleeding disorder 15 |
| RS751175089 |
PYGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Glycogen storage disease |
| RS751175344 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS751176079 |
CHKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Megaconial type congenital muscular dystrophy, Megaconial type congenital muscular dystrophy |
| RS751176093 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS751176116 |
USH2A
|
Health Risk |
Pathogenic |
Rare genetic deafness, Usher syndrome type 2A |
| RS751176402 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Recessive dystrophic epidermolysis bullosa, Recessive dystrophic epidermolysis bullosa |
| RS751177222 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis, Perry syndrome |
| RS751177541 |
IFT172
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS751178858 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
LZTR1-related disorder, LZTR1-related disorder |
| RS751179784 |
MSH6
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS751180603 |
ARSG
|
Health Risk |
Likely pathogenic |
— |
| RS751181507 |
ALDH18A1
|
Health Risk |
Pathogenic/Likely pathogenic |
ALDH18A1-related disorder, Autosomal dominant spastic paraplegia type 9 |
| RS751181600 |
WWOX
|
Health Risk |
Likely pathogenic |
Autosomal recessive spinocerebellar ataxia 12, Autosomal recessive spinocerebellar ataxia 12 |
| RS751182532 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrochondrogenesis 1, Stickler syndrome type 2 |
| RS751182540 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Brittle cornea syndrome 2, PRDM5-related disorder |
| RS751182657 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS751183646 |
IFT43
|
Health Risk |
Pathogenic |
— |
| RS751184319 |
SLC12A6
|
Health Risk |
Pathogenic/Likely pathogenic |
Agenesis of the corpus callosum with peripheral neuropathy, Agenesis of the corpus callosum with peripheral neuropathy |
| RS751184580 |
FRMD5
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with eye movement abnormalities and ataxia, Neurodevelopmental disorder with eye movement abnormalities and ataxia |
| RS751185256 |
COQ2
|
Health Risk |
risk factor |
Multiple system atrophy, Coenzyme Q10 deficiency |
| RS751185435 |
WDFY3
|
Health Risk |
Conflicting classifications of pathogenicity |
Esophageal atresia/tracheoesophageal fistula, Inborn genetic diseases |
| RS751185980 |
RETREG1
|
Health Risk |
Likely pathogenic |
Neuropathy, hereditary sensory and autonomic |
| RS751186776 |
GCDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Glutaric aciduria, type 1 |
| RS751186949 |
MYH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, proximal |
| RS751187394 |
AARS2
|
Health Risk |
Likely pathogenic |
— |
| RS751189785 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
CFTR-related disorder, CFTR-related disorder |
| RS751190049 |
TCF4
|
Health Risk |
Likely pathogenic |
Pitt-Hopkins syndrome, Pitt-Hopkins syndrome |
| RS751190453 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS751190601 |
TBCD
|
Health Risk |
Pathogenic/Likely pathogenic |
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome, Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome |
| RS751190779 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751191119 |
CCDC40
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS751191439 |
LRRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751192029 |
SLCO2A1
|
Health Risk |
Pathogenic |
Hypertrophic osteoarthropathy, primary |
| RS751192681 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A2-related disorder |
| RS751192841 |
ARID1B
|
Health Risk |
Pathogenic |
See cases, See cases |
| RS751193355 |
RSPH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia 32, Primary ciliary dyskinesia 32 |
| RS751195930 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |