| RS751326348 |
MSH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial adenomatous polyposis 4, Hereditary cancer-predisposing syndrome |
| RS751326698 |
CTSC
|
Health Risk |
Conflicting classifications of pathogenicity |
Haim-Munk syndrome, Periodontitis |
| RS751326753 |
ASPM
|
Health Risk |
Pathogenic |
Microcephaly 5, primary |
| RS751327499 |
TNPO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1F, Autosomal dominant limb-girdle muscular dystrophy type 1F |
| RS751327903 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS751327913 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, seizures |
| RS751329013 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS751329439 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS751329477 |
GABRB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, childhood absence |
| RS751329878 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS751330788 |
REEP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 77, Retinitis pigmentosa 77 |
| RS751332312 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Inborn genetic diseases |
| RS751334184 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Complex neurodevelopmental disorder, Inborn genetic diseases |
| RS751334223 |
RAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS751335857 |
CHST14
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, musculocontractural type |
| RS751337133 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS751339103 |
TBX1
|
Health Risk |
Conflicting classifications of pathogenicity |
DiGeorge syndrome, Cardiovascular phenotype |
| RS751339649 |
CSF2RB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751341214 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia type 4 |
| RS751342015 |
COL9A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751342087 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS751342895 |
RPGRIP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone-rod dystrophy 13, Leber congenital amaurosis 6 |
| RS751342972 |
LAMA3
|
Health Risk |
Pathogenic |
Epidermolysis bullosa, junctional 2A |
| RS751343288 |
KDM6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities, Inborn genetic diseases |
| RS751344423 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
CPLANE1-related disorder, Joubert syndrome 17 |
| RS751344541 |
RTTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic primordial dwarfism due to RTTN deficiency, Microcephalic primordial dwarfism due to RTTN deficiency |
| RS751344618 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Ullrich congenital muscular dystrophy 2 |
| RS751345585 |
AFG2A
|
Health Risk |
Pathogenic |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome |
| RS751346031 |
PLD1
|
Health Risk |
Pathogenic |
— |
| RS751346260 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alstrom syndrome |
| RS751346548 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS751346602 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy |
| RS751346612 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751346951 |
C1QTNF5
|
Health Risk |
Conflicting classifications of pathogenicity |
C1QTNF5-related disorder, C1QTNF5-related disorder |
| RS751347948 |
JAG2
|
Health Risk |
Likely pathogenic |
Muscular dystrophy, limb-girdle |
| RS751349850 |
FLG
|
Health Risk |
Likely pathogenic |
Ichthyosis vulgaris, Ichthyosis vulgaris |
| RS751349881 |
SEC23B
|
Health Risk |
Pathogenic |
Congenital dyserythropoietic anemia, type II |
| RS751351000 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751352401 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Schaaf-Yang syndrome, Schaaf-Yang syndrome |
| RS751352435 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS751352585 |
DNHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751353500 |
SPG7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS751354326 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia-like disorder 1, Ataxia-telangiectasia-like disorder |
| RS751354601 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS751356173 |
FMO3
|
Health Risk |
Pathogenic/Likely pathogenic |
Trimethylaminuria, Trimethylaminuria |
| RS751356206 |
EVC2
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS751356341 |
SMOC1
|
Health Risk |
Pathogenic |
Microphthalmia with limb anomalies, Microphthalmia with limb anomalies |
| RS751356878 |
KIAA0586
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS751361090 |
CEP290
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel syndrome, type 4 |
| RS751361395 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal acantholytic epidermolysis bullosa, Woolly hair-skin fragility syndrome |
| RS751362258 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS751364453 |
PHKA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen phosphorylase kinase deficiency, Glycogen storage disease IXa1 |
| RS751365374 |
ATP2A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Brody myopathy, ATP2A1-related disorder |
| RS751366915 |
TRIM8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751366974 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 29 |
| RS751367016 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS751367935 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS751368643 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS751368655 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS751369041 |
AAAS
|
Health Risk |
Pathogenic |
— |
| RS751369871 |
OTOG
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 18B, OTOG-related disorder |
| RS751370455 |
LEFTY2
|
Health Risk |
Conflicting classifications of pathogenicity |
Left-right axis malformations, Left-right axis malformations |
| RS751370687 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS751370720 |
NADK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive encephalopathy with leukodystrophy due to DECR deficiency, Progressive encephalopathy with leukodystrophy due to DECR deficiency |
| RS751370730 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS751373279 |
TRPM1
|
Health Risk |
Pathogenic |
— |
| RS751374117 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS75137449 |
NRXN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins-like syndrome 2, Pitt-Hopkins-like syndrome 2 |
| RS751375135 |
C6
|
Health Risk |
Pathogenic |
— |
| RS751375244 |
TRAPPC3
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS751375245 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS751375381 |
MEFV
|
Health Risk |
Likely pathogenic |
Familial Mediterranean fever, Familial Mediterranean fever |
| RS751375908 |
RANBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial acute necrotizing encephalopathy, Familial acute necrotizing encephalopathy |
| RS751376824 |
POLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive sclerosing poliodystrophy, Progressive external ophthalmoplegia with mitochondrial DNA deletions |
| RS751378446 |
PLCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
PLCE1-related disorder, PLCE1-related disorder |
| RS751381608 |
ZSWIM6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751381953 |
PARN
|
Health Risk |
Pathogenic |
Pulmonary fibrosis and/or bone marrow failure, Telomere-related |
| RS751382433 |
GYS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease due to muscle and heart glycogen synthase deficiency, Glycogen storage disease due to muscle and heart glycogen synthase deficiency |
| RS751384082 |
TEX15
|
Health Risk |
Pathogenic |
— |
| RS751384954 |
BBS12
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS751385266 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS751385957 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS751386365 |
RFXANK
|
Health Risk |
Likely pathogenic |
Inherited Immunodeficiency Diseases, MHC class II deficiency 2 |
| RS751386429 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Senior-Loken syndrome 8, Asphyxiating thoracic dystrophy 5 |
| RS75138661 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS751388694 |
NPHP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS751388860 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS751389585 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751390841 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS751391752 |
NIPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 6, Hereditary spastic paraplegia 6 |
| RS751392310 |
MYL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS751393552 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751393852 |
MCCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS751393950 |
HEXA
|
Health Risk |
Pathogenic/Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS751394068 |
ETFDH
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS751394716 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS751396157 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS751396984 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS751398082 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 1 |
| RS751399780 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign familial hematuria, Autosomal dominant Alport syndrome |