| RS751458185 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751458617 |
NEU1
|
Health Risk |
Likely pathogenic |
Sialidosis, Sialidosis type 2 |
| RS751459058 |
FARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation defect type 14, Hereditary spastic paraplegia 77 |
| RS751459271 |
POLR3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Inborn genetic diseases |
| RS751459281 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS751459908 |
CANT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751460221 |
PROM1
|
Health Risk |
Pathogenic |
— |
| RS751460831 |
ACO2
|
Health Risk |
Pathogenic |
ACO2-related disorder, ACO2-related disorder |
| RS751460863 |
SMS
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability Snyder type, Inborn genetic diseases |
| RS751461388 |
GNPTAB
|
Health Risk |
Pathogenic |
Mucolipidosis, Mucolipidosis |
| RS751461705 |
ARSG
|
Health Risk |
Pathogenic |
Usher syndrome, type 4 |
| RS751464024 |
CBS
|
Health Risk |
Likely pathogenic |
Classic homocystinuria, HYPERHOMOCYSTEINEMIA |
| RS751464413 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Inborn genetic diseases |
| RS751465004 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751465048 |
MLH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, hereditary nonpolyposis |
| RS751465593 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Intrauterine growth retardation, metaphyseal dysplasia |
| RS751466510 |
SYNGAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS751466686 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS751466815 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, SGCA-related disorder |
| RS751468762 |
NEXMIF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751468976 |
EIF2S3
|
Health Risk |
Likely pathogenic |
MEHMO syndrome, MEHMO syndrome |
| RS751469553 |
ESCO2
|
Health Risk |
Pathogenic |
— |
| RS751470049 |
CHST3
|
Health Risk |
Pathogenic |
Spondyloepiphyseal dysplasia with congenital joint dislocations, Spondyloepiphyseal dysplasia with congenital joint dislocations |
| RS751470493 |
HSD3B2
|
Health Risk |
Conflicting classifications of pathogenicity |
3 beta-Hydroxysteroid dehydrogenase deficiency, HSD3B2-related disorder |
| RS751470649 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS751471043 |
CD36
|
Health Risk |
Pathogenic |
See cases, See cases |
| RS751471386 |
ARL2BP
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa with or without situs inversus, Retinitis pigmentosa with or without situs inversus |
| RS751472475 |
NDUFS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS751472610 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2N, Charcot-Marie-Tooth disease type 2 |
| RS751473506 |
DYSF
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS751473818 |
FKTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Cardiovascular phenotype |
| RS751475729 |
SPEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Radio-Tartaglia syndrome, Radio-Tartaglia syndrome |
| RS751475855 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS751477326 |
TP53
|
Health Risk |
Pathogenic/Likely pathogenic |
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome |
| RS751477334 |
PNPO
|
Health Risk |
Pathogenic |
Pyridoxal phosphate-responsive seizures, Pyridoxal phosphate-responsive seizures |
| RS751477523 |
RPGRIP1L
|
Health Risk |
Pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS751477540 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS751478115 |
SCUBE3
|
Health Risk |
Pathogenic/Likely pathogenic |
Abnormality of the dentition, Abnormal facial shape |
| RS751478142 |
HSPA9
|
Health Risk |
Pathogenic |
Even-plus syndrome, Even-plus syndrome |
| RS751478782 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS751479180 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Usher syndrome |
| RS751482122 |
SCO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751482231 |
RBBP8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751482282 |
RHBDF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Palmoplantar keratoderma-esophageal carcinoma syndrome, Inborn genetic diseases |
| RS751483486 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS751484278 |
EMC1
|
Health Risk |
Likely pathogenic |
Cerebellar atrophy, visual impairment |
| RS751484879 |
BCS1L
|
Health Risk |
Pathogenic/Likely pathogenic |
GRACILE syndrome, Pili torti-deafness syndrome |
| RS75148532 |
ABCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCC2-related disorder, ABCC2-related disorder |
| RS751486476 |
CLN6
|
Health Risk |
Conflicting classifications of pathogenicity |
Ceroid lipofuscinosis, neuronal |
| RS751486617 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS751488725 |
HEXB
|
Health Risk |
Pathogenic |
Sandhoff disease, Sandhoff disease |
| RS751490043 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS751490881 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy |
| RS751491596 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Inborn genetic diseases |
| RS751492244 |
CFAP206
|
Health Risk |
Pathogenic |
Abnormal sperm tail morphology, Abnormal sperm tail morphology |
| RS751493277 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS751494076 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS751494785 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS751494861 |
SLC12A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 34 |
| RS751495086 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS751495618 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
FGFR2-related craniosynostosis, FGFR2-related craniosynostosis |
| RS751496223 |
CLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis 5 |
| RS751496558 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Amyotrophic lateral sclerosis |
| RS751497896 |
NBN
|
Health Risk |
Likely pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS751499706 |
ATAD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hyperekplexia 4, Hyperekplexia 4 |
| RS751501857 |
PRKAR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carney complex, type 1 |
| RS751502450 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS751502842 |
TTN
|
Health Risk |
Pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS751503394 |
RECQL4
|
Health Risk |
Likely pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS751505614 |
GCK
|
Health Risk |
Pathogenic |
— |
| RS751506204 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, PEX1-related disorder |
| RS751506325 |
CR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS751507296 |
ACADS
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of butyryl-CoA dehydrogenase, Deficiency of butyryl-CoA dehydrogenase |
| RS751507771 |
PEX26
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 7A (Zellweger), Peroxisome biogenesis disorder 7B |
| RS751507887 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Inborn genetic diseases |
| RS751507915 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS751509135 |
NEDD4L
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751509404 |
ANKS6
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 16, Inborn genetic diseases |
| RS751511116 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS751511204 |
LYST
|
Health Risk |
Conflicting classifications of pathogenicity |
Chédiak-Higashi syndrome, Chédiak-Higashi syndrome |
| RS751511532 |
USP53
|
Health Risk |
Pathogenic |
Cholestasis, progressive familial intrahepatic |
| RS751511778 |
PPOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Variegate porphyria, Variegate porphyria |
| RS751511835 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751512442 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stickler syndrome type 2, Fibrochondrogenesis 1 |
| RS751512548 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS751513015 |
GLI2
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly 9, Postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome |
| RS751513869 |
NFKBIA
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectodermal dysplasia and immunodeficiency 2, NFKBIA-related disorder |
| RS751514645 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, Inborn genetic diseases |
| RS751515136 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS751515174 |
CANT1
|
Health Risk |
Pathogenic |
— |
| RS751515818 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS751516224 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS751516838 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated Nonsyndromic Congenital Heart Disease, Alagille syndrome due to a JAG1 point mutation |
| RS751517725 |
TMEM67
|
Health Risk |
Pathogenic |
Joubert syndrome 6, Joubert syndrome |
| RS751518356 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS751519679 |
DDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of aromatic-L-amino-acid decarboxylase, Deficiency of aromatic-L-amino-acid decarboxylase |
| RS751520054 |
MYO5B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital microvillous atrophy, Congenital microvillous atrophy |
| RS75152012 |
ALB
|
Health Risk |
Pathogenic |
Analbuminemia, Analbuminemia |
| RS751520590 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS751521888 |
RPGRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 1, Cone-rod dystrophy 13 |