| RS751589863 |
RDH12
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Leber congenital amaurosis 13 |
| RS751589956 |
TULP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Leber congenital amaurosis 15 |
| RS751589999 |
ZNF142
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental disorder with impaired speech and hyperkinetic movements, Neurodevelopmental disorder with impaired speech and hyperkinetic movements |
| RS751590073 |
ASL
|
Health Risk |
Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS751590336 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS751591418 |
ABCC8
|
Health Risk |
Pathogenic |
— |
| RS751591632 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS751591853 |
APC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751592419 |
HEXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Sandhoff disease, Sandhoff disease |
| RS751592819 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 27 |
| RS751592993 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Myofibrillar myopathy 5 |
| RS751593187 |
B4GALNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS751594548 |
AMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscle AMP deaminase deficiency, Muscle AMP deaminase deficiency |
| RS751598619 |
EXT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Exostoses, multiple |
| RS751599201 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS751599203 |
BCKDHB
|
Health Risk |
Pathogenic/Likely pathogenic |
Maple syrup urine disease, BCKDHB-related disorder |
| RS751600209 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Macular degeneration |
| RS751600310 |
MTHFS;ST20-MTHFS
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751600686 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS751600886 |
PHKG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease IXc, PHKG2-related disorder |
| RS751600925 |
KCNV2
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS751602407 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS751603525 |
SKIC3
|
Health Risk |
Pathogenic |
— |
| RS751603831 |
MOCS1
|
Health Risk |
Pathogenic |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A |
| RS751603969 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS751604155 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS751604696 |
DHCR7
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Lemli-Opitz syndrome, Inborn genetic diseases |
| RS751604761 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS751604858 |
BBS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 2, Bardet-Biedl syndrome |
| RS751605791 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS751608665 |
CLCNKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 3, Bartter disease type 4B |
| RS751609154 |
RD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 12, Leber congenital amaurosis 12 |
| RS75160992 |
CYB5A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751610164 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS751610198 |
CAD
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 50 |
| RS751610641 |
TCF20
|
Health Risk |
Pathogenic |
Developmental delay with variable intellectual impairment and behavioral abnormalities, Neurodevelopmental abnormality |
| RS751610886 |
DNAAF4
|
Health Risk |
Pathogenic/Likely pathogenic |
DNAAF4-related disorder, Primary ciliary dyskinesia 25 |
| RS751612997 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Otospondylomegaepiphyseal dysplasia, autosomal recessive |
| RS751613059 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gorlin syndrome |
| RS751613983 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS751615449 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, AKAP9-related disorder |
| RS751618728 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS751619487 |
RAB23
|
Health Risk |
Conflicting classifications of pathogenicity |
Carpenter syndrome, RAB23-related Carpenter syndrome |
| RS751621364 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS751621733 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS751622198 |
HFM1
|
Health Risk |
Pathogenic |
Premature ovarian failure 9, Premature ovarian failure 9 |
| RS751622656 |
SMAD6
|
Health Risk |
Pathogenic |
Radioulnar synostosis, Radioulnar synostosis |
| RS751623760 |
ERCC6
|
Health Risk |
Pathogenic/Likely pathogenic |
7 conditions, 7 conditions |
| RS751624492 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic acidemia |
| RS751625937 |
ALPL
|
Health Risk |
Likely pathogenic |
Hypophosphatasia, Hypophosphatasia |
| RS751625944 |
LIPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Lysosomal acid lipase deficiency, Wolman disease |
| RS751627340 |
IRF2BPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751627510 |
GSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish type amyloidosis, Finnish type amyloidosis |
| RS751628735 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS751628774 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS751628871 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS751629013 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS751629184 |
NPHP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 3, NPHP3-related Meckel-like syndrome |
| RS751629274 |
MBD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751629543 |
EYS
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 25, Autosomal recessive retinitis pigmentosa |
| RS751629644 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS75163090 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinal dystrophy |
| RS751631188 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiomyopathy |
| RS751631278 |
NUBPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 21 |
| RS751632633 |
PUS1
|
Health Risk |
Likely pathogenic |
Myopathy, lactic acidosis |
| RS751633537 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Pheochromocytoma/paraganglioma syndrome 5, Mitochondrial complex II deficiency |
| RS751635016 |
ADA
|
Health Risk |
Likely pathogenic |
Severe combined immunodeficiency disease, Severe combined immunodeficiency |
| RS751635650 |
RP1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 1, Retinitis pigmentosa 1 |
| RS751636782 |
CRELD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrioventricular septal defect, susceptibility to |
| RS751637699 |
COQ8A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS751637843 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS751637847 |
MYBPC3
|
Health Risk |
Likely pathogenic |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy |
| RS751638632 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Schuurs-Hoeijmakers syndrome |
| RS751638930 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS751639011 |
KIF11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751639773 |
GAA
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type II |
| RS751640004 |
RTEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 5 |
| RS751640052 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS751641438 |
COG5
|
Health Risk |
Likely pathogenic |
COG5-congenital disorder of glycosylation, COG5-congenital disorder of glycosylation |
| RS751641518 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Frasier syndrome, Drash syndrome |
| RS751641706 |
DNAH5
|
Health Risk |
Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS751642419 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS751643248 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hyperinsulinism, Transitory neonatal diabetes mellitus |
| RS751643938 |
OGDHL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Yoon-Bellen neurodevelopmental syndrome |
| RS751644763 |
NMNAT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Cone-rod dystrophy |
| RS751646059 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS751646100 |
VPS13B
|
Health Risk |
Pathogenic |
— |
| RS751646311 |
HSD17B4
|
Health Risk |
Pathogenic |
Bifunctional peroxisomal enzyme deficiency, Perrault syndrome |
| RS751646468 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS751647405 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Inborn genetic diseases |
| RS751648064 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS751649145 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS751649334 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Hypercholesterolemia |
| RS751650356 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, FLNB-Related Spectrum Disorders |
| RS751650834 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751651742 |
SNTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS751651780 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS751651833 |
KRIT1
|
Health Risk |
Pathogenic |
Cerebral cavernous malformation, Cerebral cavernous malformation |
| RS751653049 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS751653739 |
SLX4
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |