| RS751713111 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Fraumeni syndrome, Hereditary cancer-predisposing syndrome |
| RS751713432 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS751713601 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperimmunoglobulin D with periodic fever, Mevalonic aciduria |
| RS751713917 |
CYP7B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 5A, Spastic paraplegia |
| RS751714292 |
SCN8A
|
Health Risk |
Likely pathogenic |
— |
| RS751715193 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS751715969 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiomyopathy |
| RS751716762 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS751717131 |
MMAA
|
Health Risk |
Likely pathogenic |
Methylmalonic aciduria, cblA type |
| RS751721557 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS751724804 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS751725130 |
ENPP1
|
Health Risk |
Pathogenic |
Arterial calcification, generalized |
| RS751726505 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 5 |
| RS751726519 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 5 with or without anosmia, CHARGE syndrome |
| RS751726770 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS751728141 |
RNF13
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751728774 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS751728796 |
CASP10
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune lymphoproliferative syndrome type 2A, Autoimmune lymphoproliferative syndrome type 2A |
| RS751728820 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS751732786 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, NPHP4-related disorder |
| RS751733167 |
CIITA
|
Health Risk |
Pathogenic |
MHC class II deficiency, MHC class II deficiency |
| RS751733169 |
STIM1
|
Health Risk |
Pathogenic |
Combined immunodeficiency due to STIM1 deficiency, Myopathy with tubular aggregates |
| RS751733505 |
TUBB4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelinating leukodystrophy 6, Hypomyelinating leukodystrophy 6 |
| RS751733811 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS751734028 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS751734367 |
CEP104
|
Health Risk |
Likely pathogenic |
Joubert syndrome and related disorders, Joubert syndrome 25 |
| RS751734985 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome 3, Joubert syndrome |
| RS751735028 |
CANT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Desbuquois dysplasia 1, Desbuquois dysplasia 1 |
| RS751741065 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751742258 |
HSD17B4
|
Health Risk |
Pathogenic |
Perrault syndrome 1, Perrault syndrome 1 |
| RS751742575 |
GCDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Glutaric aciduria, type 1 |
| RS751742955 |
AP4M1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 50, Hereditary spastic paraplegia 50 |
| RS751744545 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Hereditary cancer-predisposing syndrome |
| RS751744651 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive Alport syndrome |
| RS751745906 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS751746401 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS751748298 |
C6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751748445 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS751749614 |
COL17A1
|
Health Risk |
Likely pathogenic |
Amelogenesis imperfecta type 1A, Amelogenesis imperfecta type 1A |
| RS751749720 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Pulmonary venoocclusive disease 1 |
| RS751749918 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome |
| RS751749989 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schizencephaly, Retinal arterial tortuosity |
| RS751750112 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS751750631 |
NDUFAF5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751751349 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2O, Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability) |
| RS751752830 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Pulmonary fibrosis and/or bone marrow failure, Telomere-related |
| RS751753112 |
BBS1
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome 1, Bardet-Biedl syndrome |
| RS751753677 |
COASY
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodegeneration with brain iron accumulation 6, Pontocerebellar hypoplasia |
| RS751753975 |
HPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinemia type III, Hawkinsinuria |
| RS751754026 |
CACNB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Episodic ataxia type 5 |
| RS751754128 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS751754608 |
PKHD1
|
Health Risk |
Likely pathogenic |
Polycystic kidney disease 4, Polycystic kidney disease 4 |
| RS751754677 |
TBCD
|
Health Risk |
Pathogenic/Likely pathogenic |
Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome, TBCD-related disorder |
| RS751755276 |
MBTPS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, Osteogenesis imperfecta |
| RS751756042 |
GCK
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young, Maturity-onset diabetes of the young |
| RS751757203 |
FANCC
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Fanconi anemia |
| RS75175945 |
AEBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751759733 |
SLC12A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kilquist syndrome, Hearing loss |
| RS751759820 |
STAR
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lipoid adrenal hyperplasia due to STAR deficency, Congenital lipoid adrenal hyperplasia due to STAR deficency |
| RS751759887 |
SCN1A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS751760156 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS751761766 |
HNF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 3, Maturity-onset diabetes of the young |
| RS751762149 |
KIF22
|
Health Risk |
Pathogenic |
Spondyloepimetaphyseal dysplasia with multiple dislocations, Spondyloepimetaphyseal dysplasia with multiple dislocations |
| RS751763023 |
IMPDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Inborn genetic diseases |
| RS751763157 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS751763527 |
TYRP1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS751764482 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS751764864 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS751764908 |
COQ4
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome, Spastic ataxia 10 |
| RS751765105 |
INVS
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS751766259 |
PHYH
|
Health Risk |
Likely pathogenic |
Phytanic acid storage disease, Phytanic acid storage disease |
| RS751767695 |
RNASEH2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 3, Aicardi-Goutieres syndrome 3 |
| RS751768052 |
WNT2B
|
Health Risk |
Pathogenic |
— |
| RS751768343 |
CYP1B1
|
Health Risk |
Likely pathogenic |
Glaucoma 3A, Glaucoma 3 |
| RS751768659 |
COL7A1
|
Health Risk |
Pathogenic |
— |
| RS751769266 |
WDR35
|
Health Risk |
Conflicting classifications of pathogenicity |
WDR35-related disorder, Cranioectodermal dysplasia 2 |
| RS751769391 |
MYO7A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 2, Usher syndrome |
| RS751769427 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Asphyxiating thoracic dystrophy 3 |
| RS751771156 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS751771991 |
ADCY10
|
Health Risk |
Likely pathogenic |
— |
| RS751772225 |
EVC
|
Health Risk |
Pathogenic |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS751772396 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Focal segmental glomerulosclerosis 5 |
| RS751773278 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751773510 |
ALOX12B
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 2, Autosomal recessive congenital ichthyosis 2 |
| RS751774080 |
HPGD
|
Health Risk |
Pathogenic |
Hypertrophic osteoarthropathy, primary |
| RS751775497 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS751776251 |
SLC34A3
|
Health Risk |
Pathogenic |
— |
| RS751776479 |
FAT4
|
Health Risk |
Pathogenic |
— |
| RS751778243 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS751778283 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS751778396 |
AP5Z1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia 48 |
| RS751778614 |
ENG
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Hereditary hemorrhagic telangiectasia |
| RS751778923 |
MAT1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hepatic methionine adenosyltransferase deficiency, Hepatic methionine adenosyltransferase deficiency |
| RS751779219 |
TMEM127
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pheochromocytoma and paraganglioma, Hereditary cancer-predisposing syndrome |
| RS751779314 |
APRT
|
Health Risk |
Likely pathogenic |
Adenine phosphoribosyltransferase deficiency, Adenine phosphoribosyltransferase deficiency |
| RS751779659 |
SATB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Chromosome 2q32-q33 deletion syndrome, Chromosome 2q32-q33 deletion syndrome |
| RS751779702 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS751780309 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS751780827 |
POGLUT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751780925 |
FRAS1
|
Health Risk |
Pathogenic |
— |