| RS751523859 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751524927 |
TET3
|
Health Risk |
Likely pathogenic |
Multiple myeloma, Multiple myeloma |
| RS751526033 |
CYP24A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercalcemia, infantile |
| RS751526095 |
HPS5
|
Health Risk |
Likely pathogenic |
— |
| RS751526607 |
IDH3B
|
Health Risk |
Likely pathogenic |
— |
| RS751526974 |
VSX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated microphthalmia 2, Microphthalmia |
| RS751527253 |
NPHP3
|
Health Risk |
Pathogenic/Likely pathogenic |
NPHP3-related Meckel-like syndrome, Nephronophthisis |
| RS751528808 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group O |
| RS751528863 |
RDX
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751529827 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751532649 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS751533302 |
SCN1A
|
Health Risk |
Likely pathogenic |
Severe myoclonic epilepsy in infancy, Generalized epilepsy with febrile seizures plus |
| RS751534116 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS751534948 |
CHD4
|
Health Risk |
Likely pathogenic |
Sifrim-Hitz-Weiss syndrome, Sifrim-Hitz-Weiss syndrome |
| RS751534972 |
SI
|
Health Risk |
Pathogenic/Likely pathogenic |
Sucrase-isomaltase deficiency, Sucrase-isomaltase deficiency |
| RS751535164 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS751535193 |
COL7A1
|
Health Risk |
Pathogenic |
Recessive dystrophic epidermolysis bullosa, Epidermolysis bullosa dystrophica |
| RS751537483 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS751537617 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
AHDC1-related disorder, AHDC1-related disorder |
| RS751537797 |
QARS1
|
Health Risk |
Pathogenic |
Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome, Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome |
| RS751538672 |
PCCB
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS751538967 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS751539473 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 23, Usher syndrome type 1D |
| RS751539788 |
SETD5
|
Health Risk |
Pathogenic |
— |
| RS751540983 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS751542188 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS751543129 |
PTDSS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751545508 |
TUBGCP4
|
Health Risk |
Pathogenic |
— |
| RS751545674 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS751546090 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS751546336 |
SLC1A4
|
Health Risk |
Likely pathogenic |
— |
| RS751546658 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS751547595 |
IDUA
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS751547630 |
SERAC1
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS751548566 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS751548925 |
ARSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Chondrodysplasia punctata, brachytelephalangic |
| RS751549678 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal spinal muscular atrophy 1, Charcot-Marie-Tooth disease |
| RS751551400 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS751551929 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Kufor-Rakeb syndrome |
| RS751553150 |
CACNA1D
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751554200 |
LPL
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS751555693 |
EIF2B4
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS751556332 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, ACADVL-related disorder |
| RS751556970 |
COQ9
|
Health Risk |
Pathogenic |
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome |
| RS751557097 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyltransferase II deficiency, Encephalopathy |
| RS751557279 |
MYO18B
|
Health Risk |
Pathogenic |
— |
| RS751557477 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751557941 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, PIEZO1-related disorder |
| RS751558324 |
FERMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751559319 |
MPV17
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751559990 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS751560567 |
FOXF1
|
Health Risk |
Pathogenic |
FOXF1-related disorder, FOXF1-related disorder |
| RS751560923 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS751561029 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Alport syndrome |
| RS75156162 |
CRYGD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cataract 4 multiple types, Aculeiform cataract |
| RS751562376 |
DNMT3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Tatton-Brown-Rahman overgrowth syndrome, Tatton-Brown-Rahman overgrowth syndrome |
| RS751563078 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Noonan syndrome 9 |
| RS751563432 |
POLE2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751564052 |
NKX2-5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial septal defect 7, Cardiovascular phenotype |
| RS751564248 |
OTOF
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 9, Autosomal recessive nonsyndromic hearing loss 9 |
| RS751564290 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS751564566 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS751564716 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS751564985 |
SIRT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751565055 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS751565386 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal dysplasia type I, Trichorhinophalangeal syndrome |
| RS751566392 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal acantholytic epidermolysis bullosa, Arrhythmogenic right ventricular dysplasia 8 |
| RS751567476 |
NBN
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS751568153 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS751569402 |
DEAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS751569508 |
NCOR1
|
Health Risk |
Likely pathogenic |
Developmental delay, Hyperlaxity |
| RS751570713 |
NBN
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS751570775 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Hereditary cancer-predisposing syndrome |
| RS751571034 |
GABRA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Epilepsy |
| RS751571336 |
KDSR
|
Health Risk |
Likely pathogenic |
Erythrokeratodermia variabilis et progressiva 4, Erythrokeratodermia variabilis et progressiva 4 |
| RS751571463 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS751571517 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS751572082 |
RET
|
Health Risk |
Likely pathogenic |
Aganglionic megacolon, Aganglionic megacolon |
| RS751572448 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS751573593 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
GLUT1 deficiency syndrome 1, autosomal recessive |
| RS751574257 |
ATM
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS751574733 |
CYP27B1
|
Health Risk |
Conflicting classifications of pathogenicity |
CYP27B1-related disorder, Vitamin D-dependent rickets |
| RS751575036 |
SNAP29
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypomyelinating leukodystrophy 2, CEDNIK syndrome |
| RS751575627 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS751577470 |
RHAG
|
Health Risk |
Conflicting classifications of pathogenicity |
Rh-null, regulator type |
| RS751581199 |
SZT2
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS751581475 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS751581773 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS751582616 |
PIK3R1
|
Health Risk |
Pathogenic/Likely pathogenic |
Vascular Malformations and Overgrowth, CLOVES syndrome |
| RS751582760 |
SMARCAL1
|
Health Risk |
Pathogenic/Likely pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS751583656 |
GCDH
|
Health Risk |
Pathogenic |
Glutaric aciduria, type 1 |
| RS751583919 |
IFT74
|
Health Risk |
Likely pathogenic |
Joubert syndrome 40, Joubert syndrome 40 |
| RS75158395 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS751584939 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751585626 |
CHD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Sifrim-Hitz-Weiss syndrome, Sifrim-Hitz-Weiss syndrome |
| RS751585966 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751586969 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, FLNB-Related Spectrum Disorders |
| RS751587466 |
TGFBR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 2 |
| RS751587806 |
SLC4A11
|
Health Risk |
Pathogenic |
Corneal dystrophy-perceptive deafness syndrome, Congenital hereditary endothelial dystrophy of cornea |
| RS751589349 |
RNF125
|
Health Risk |
Conflicting classifications of pathogenicity |
Tenorio syndrome, Tenorio syndrome |