| RS751781089 |
MSH4
|
Health Risk |
Likely pathogenic |
Non-obstructive azoospermia, Non-obstructive azoospermia |
| RS751781253 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS751781504 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Inborn genetic diseases |
| RS751782722 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group F |
| RS751782763 |
CDH4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751784955 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS751785066 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia 3 |
| RS751787202 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS751787590 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS751787816 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS751788298 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS751788327 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS751788879 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Pituitary adenoma 5 |
| RS751789670 |
CDKL5
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 2 |
| RS751789834 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS751790458 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Pallister-Hall syndrome, Greig cephalopolysyndactyly syndrome |
| RS751790521 |
RAPSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 11 |
| RS751791095 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS751792216 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS751794368 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS751795238 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS751795256 |
FANCM
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia |
| RS751795794 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751795987 |
COL1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Osteogenesis imperfecta type I |
| RS751796325 |
ATL1
|
Health Risk |
Likely pathogenic |
— |
| RS751797884 |
GSS
|
Health Risk |
Pathogenic |
Glutathione synthetase deficiency with 5-oxoprolinuria, Glutathione synthetase deficiency with 5-oxoprolinuria |
| RS751798253 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS751798471 |
SH3BP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrous dysplasia of jaw, Fibrous dysplasia of jaw |
| RS751798708 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS751798987 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS751799266 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS751800062 |
MSH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Endometrial carcinoma |
| RS751802785 |
PCLO
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751802868 |
ACBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS75180385 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS751803871 |
TYMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 1, Mitochondrial DNA depletion syndrome 1 |
| RS751804284 |
MMUT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751804613 |
ALMS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Alstrom syndrome, Cardiovascular phenotype |
| RS751804837 |
CD36
|
Health Risk |
Likely pathogenic |
Platelet-type bleeding disorder 10, Platelet-type bleeding disorder 10 |
| RS751805500 |
NGLY1
|
Health Risk |
Pathogenic |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS751807811 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS751808345 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Familial hemiplegic migraine |
| RS751809412 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS751809418 |
HACE1
|
Health Risk |
Pathogenic |
Spastic paraplegia-severe developmental delay-epilepsy syndrome, Spastic paraplegia-severe developmental delay-epilepsy syndrome |
| RS751809435 |
PTPN23
|
Health Risk |
Conflicting classifications of pathogenicity |
Global developmental delay, Brain atrophy |
| RS751809792 |
SPTB
|
Health Risk |
Pathogenic |
Hereditary spherocytosis type 2, Hereditary spherocytosis type 2 |
| RS751809997 |
NPHS1
|
Health Risk |
Pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS751810874 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 11 |
| RS751810893 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS751812338 |
PPARG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751812984 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS751813170 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, MEGF10-related myopathy |
| RS751815253 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751815309 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751815828 |
STAR
|
Health Risk |
Pathogenic |
— |
| RS751817675 |
HNF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cysts and diabetes syndrome, Maturity-onset diabetes of the young |
| RS751818062 |
MKS1
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 13, Bardet-Biedl syndrome 13 |
| RS751818701 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
AHDC1-related intellectual disability - obstructive sleep apnea - mild dysmorphism syndrome, Inborn genetic diseases |
| RS751818903 |
ADAMTS18
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS751819044 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS751819645 |
COX15
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardioencephalomyopathy, fatal infantile |
| RS751820545 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS751821289 |
ETFDH
|
Health Risk |
Likely pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS751822337 |
GUCY2D
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 1, Leber congenital amaurosis 1 |
| RS751822516 |
CNGB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS751822565 |
GLDC
|
Health Risk |
Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS751822606 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751822769 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS751823180 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome 3, Joubert syndrome 1 |
| RS751823989 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS751824761 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, FBN2-related disorder |
| RS751825185 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS751825784 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751826777 |
ABCC8
|
Health Risk |
Pathogenic |
Type 2 diabetes mellitus, Type 2 diabetes mellitus |
| RS751828098 |
NPHP3
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS751828447 |
SLC35C1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukocyte adhesion deficiency type II, Leukocyte adhesion deficiency type II |
| RS751828470 |
MMACHC;PRDX1
|
Health Risk |
Pathogenic |
METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA, cblC TYPE |
| RS751829128 |
PHOX2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital central hypoventilation, Neuroblastoma |
| RS751829413 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS751829426 |
PEX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder 1A (Zellweger), Peroxisome biogenesis disorder 1B |
| RS751830146 |
SMC5
|
Health Risk |
Pathogenic |
Atelis syndrome 2, Atelis syndrome 2 |
| RS75183025 |
FOXRED1
|
Health Risk |
Conflicting classifications of pathogenicity |
FOXRED1-related disorder, FOXRED1-related disorder |
| RS751831606 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 4 |
| RS751832374 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751833826 |
MTRR
|
Health Risk |
Likely pathogenic |
Methylcobalamin deficiency type cblE, Methylcobalamin deficiency type cblE |
| RS751834233 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Lymphangiomyomatosis |
| RS751834545 |
RAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS751838040 |
ERCC6
|
Health Risk |
Pathogenic/Likely pathogenic |
Cockayne syndrome type 2, DE SANCTIS-CACCHIONE SYNDROME |
| RS751838091 |
WHRN
|
Health Risk |
Likely pathogenic |
Usher syndrome, Usher syndrome |
| RS751838285 |
STRA6
|
Health Risk |
Likely pathogenic |
Matthew-Wood syndrome, Matthew-Wood syndrome |
| RS751838296 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS751839903 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS751840434 |
NKAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS751840512 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS751840699 |
TMEM231
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel syndrome, type 11 |
| RS751842443 |
CHRNA2
|
Health Risk |
Likely pathogenic |
— |
| RS75184268 |
SLX4
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group P |
| RS751844313 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Stargardt disease |
| RS751844801 |
CCDC39
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 14, Primary ciliary dyskinesia |
| RS751844947 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Inborn genetic diseases |