ZSWIM6 Chromosome 5

Zinc finger SWIM-type containing 6
50 variants 50 Health Risk

Upload your DNA to see your personal genotypes for variants in ZSWIM6.

What This Gene Does
The protein encoded by this gene contains a zinc finger SWI2/SNF2 and MuDR (SWIM) domain. Proteins with SWIM domains have been found in a diverse number of species and are predicted to interact with DNA or proteins. Mutations in this gene result in acromelic frontonasal dysostosis. [provided by RefSeq, Apr 2017]
Gene Info
Gene Group
Zinc fingers SWIM-type
Locus Type
gene with protein product
Location
5q12.1
Ensembl
ENSG00000130449
Associated Conditions (7)
Neurodevelopmental disorder with movement abnormalities
abnormal gait
and autistic features
Inborn genetic diseases
Acromelic frontonasal dysostosis
ZSWIM6 related intellectual disability
ZSWIM6-related disorder
Key Variants
RS1046738327
Conflicting classifications of pathogenicity
Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
Health Risk
RS1178371530
Conflicting classifications of pathogenicity
Health Risk
RS1184623630
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1215325430
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1251801615
Conflicting classifications of pathogenicity
Inborn genetic diseases, Neurodevelopmental disorder with movement abnormalities, abnormal gait
Health Risk
RS1257102056
Conflicting classifications of pathogenicity
Acromelic frontonasal dysostosis, Neurodevelopmental disorder with movement abnormalities, abnormal gait
Health Risk
RS1262946696
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1288894654
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1346946485
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS138406248
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1389523495
Conflicting classifications of pathogenicity
Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
Health Risk
RS1402175424
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
All Variants (50)
RSID Category Clinical Significance Conditions
RS1046738327 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS1178371530 Health Risk Conflicting classifications of pathogenicity
RS1184623630 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1215325430 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1251801615 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Neurodevelopmental disorder with movement abnormalities, abnormal gait
RS1257102056 Health Risk Conflicting classifications of pathogenicity Acromelic frontonasal dysostosis, Neurodevelopmental disorder with movement abnormalities, abnormal gait
RS1262946696 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1288894654 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1346946485 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS138406248 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1389523495 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS1402175424 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1421046512 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1456197449 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS148746224 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS181002879 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS191155035 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS2112275093 Health Risk Conflicting classifications of pathogenicity
RS2112294273 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS2478390820 Health Risk Conflicting classifications of pathogenicity
RS370738954 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS372466113 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS373808727 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS375378529 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS376792824 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS528020839 Health Risk Conflicting classifications of pathogenicity
RS553418522 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS561434876 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS571067306 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS745988643 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS747444881 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS751381608 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS760505023 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS763282681 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS766238385 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS772566819 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS779283808 Health Risk Conflicting classifications of pathogenicity Acromelic frontonasal dysostosis, Inborn genetic diseases, Inborn genetic diseases
RS780828160 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS864309616 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases, Inborn genetic diseases
RS896435221 Health Risk Conflicting classifications of pathogenicity Acromelic frontonasal dysostosis, Neurodevelopmental disorder with movement abnormalities, abnormal gait
RS896504353 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS921808376 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS943024318 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Acromelic frontonasal dysostosis, Neurodevelopmental disorder with movement abnormalities
RS955750160 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS976654292 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder with movement abnormalities, abnormal gait, and autistic features
RS983495066 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS995265434 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1554041457 Health Risk Likely pathogenic
RS1554041295 Health Risk Pathogenic/Likely pathogenic ZSWIM6 related intellectual disability, Neurodevelopmental disorder with movement abnormalities, abnormal gait
RS587777695 Health Risk Pathogenic/Likely pathogenic Acromelic frontonasal dysostosis, Inborn genetic diseases, Acromelic frontonasal dysostosis
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