RFX7 Chromosome 15

Regulatory factor X7
10 variants 10 Health Risk

Upload your DNA to see your personal genotypes for variants in RFX7.

What This Gene Does
RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).[supplied by OMIM, Mar 2009]
Gene Info
Gene Group
Regulatory factor X family
Locus Type
gene with protein product
Location
15q21.3
Ensembl
ENSG00000181827
Associated Conditions (7)
Neurodevelopmental disorder
Inborn genetic diseases
RFX7-related disorder
Intellectual developmental disorder
autosomal dominant 71
with behavioral abnormalities
See cases
Key Variants
All Variants (10)
RSID Category Clinical Significance Conditions
RS766009038 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental disorder, Neurodevelopmental disorder
RS2504988812 Health Risk Likely pathogenic Inborn genetic diseases, Inborn genetic diseases
RS2504989046 Health Risk Likely pathogenic
RS2504989200 Health Risk Likely pathogenic RFX7-related disorder, RFX7-related disorder
RS2504987137 Health Risk Pathogenic Intellectual developmental disorder, autosomal dominant 71, with behavioral abnormalities
RS2504987254 Health Risk Pathogenic Intellectual developmental disorder, autosomal dominant 71, with behavioral abnormalities
RS750801787 Health Risk Pathogenic Intellectual developmental disorder, autosomal dominant 71, with behavioral abnormalities
RS764917109 Health Risk Pathogenic
RS2504987146 Health Risk Pathogenic/Likely pathogenic See cases, Intellectual developmental disorder, autosomal dominant 71
RS749745135 Health Risk Pathogenic/Likely pathogenic Intellectual developmental disorder, autosomal dominant 71, with behavioral abnormalities
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