AUTS2 Chromosome 7

Activator of transcription and developmental regulator AUTS2
141 variants 141 Health Risk

Upload your DNA to see your personal genotypes for variants in AUTS2.

What This Gene Does
This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2014]
Associated Conditions (17)
See cases
AUTS2-related disorder
Inborn genetic diseases
Autism spectrum disorder due to AUTS2 deficiency
Intellectual disability
Neurodevelopmental abnormality
Autism spectrum disorder
Global developmental delay
Autism
Syndromic intellectual disability
Pierre Robin-like syndrome
Multiple congenital anomalies
Corpus callosum
agenesis of
Congenital cerebellar hypoplasia
Developmental disorder
autosomal dominant 57
Key Variants
RS1051952947
Conflicting classifications of pathogenicity
See cases, AUTS2-related disorder, Inborn genetic diseases
Health Risk
RS1057521756
Conflicting classifications of pathogenicity
Health Risk
RS1206101901
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1223142286
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1277387034
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1289630665
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS1311127815
Conflicting classifications of pathogenicity
Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
Health Risk
RS1340261250
Conflicting classifications of pathogenicity
Inborn genetic diseases, Autism spectrum disorder due to AUTS2 deficiency, Inborn genetic diseases
Health Risk
RS1354737257
Conflicting classifications of pathogenicity
Health Risk
RS1368494641
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS143679158
Conflicting classifications of pathogenicity
Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
Health Risk
RS146706542
Conflicting classifications of pathogenicity
AUTS2-related disorder, Inborn genetic diseases, AUTS2-related disorder
Health Risk
All Variants (141)
RSID Category Clinical Significance Conditions
RS1051952947 Health Risk Conflicting classifications of pathogenicity See cases, AUTS2-related disorder, Inborn genetic diseases
RS1057521756 Health Risk Conflicting classifications of pathogenicity
RS1206101901 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1223142286 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1277387034 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1289630665 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1311127815 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS1340261250 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Autism spectrum disorder due to AUTS2 deficiency, Inborn genetic diseases
RS1354737257 Health Risk Conflicting classifications of pathogenicity
RS1368494641 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS143679158 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS146706542 Health Risk Conflicting classifications of pathogenicity AUTS2-related disorder, Inborn genetic diseases, AUTS2-related disorder
RS147106727 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1471720771 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1475279630 Health Risk Conflicting classifications of pathogenicity
RS148604002 Health Risk Conflicting classifications of pathogenicity AUTS2-related disorder, Intellectual disability, AUTS2-related disorder
RS150219264 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS150765660 Health Risk Conflicting classifications of pathogenicity
RS1583913715 Health Risk Conflicting classifications of pathogenicity
RS1789934246 Health Risk Conflicting classifications of pathogenicity Neurodevelopmental abnormality, Inborn genetic diseases, See cases
RS1791806791 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder, Autism spectrum disorder
RS1791810429 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS199945820 Health Risk Conflicting classifications of pathogenicity
RS200108105 Health Risk Conflicting classifications of pathogenicity
RS200355149 Health Risk Conflicting classifications of pathogenicity
RS201559855 Health Risk Conflicting classifications of pathogenicity
RS2129561583 Health Risk Conflicting classifications of pathogenicity
RS2484637936 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS2484682116 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS2484682263 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS2484986777 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder, Autism spectrum disorder
RS2485031011 Health Risk Conflicting classifications of pathogenicity
RS369119031 Health Risk Conflicting classifications of pathogenicity AUTS2-related disorder, AUTS2-related disorder
RS369919917 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS370456436 Health Risk Conflicting classifications of pathogenicity
RS372882374 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS375948367 Health Risk Conflicting classifications of pathogenicity
RS376584055 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS534033649 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Inborn genetic diseases, Autism spectrum disorder due to AUTS2 deficiency
RS538005366 Health Risk Conflicting classifications of pathogenicity Global developmental delay, Autism, Autism spectrum disorder due to AUTS2 deficiency
RS540878144 Health Risk Conflicting classifications of pathogenicity Syndromic intellectual disability, Syndromic intellectual disability
RS543645962 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Inborn genetic diseases, Autism spectrum disorder due to AUTS2 deficiency
RS555021087 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS565156541 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS577323013 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, AUTS2-related disorder, Inborn genetic diseases
RS749092558 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS749176066 Health Risk Conflicting classifications of pathogenicity Autism spectrum disorder due to AUTS2 deficiency, Autism spectrum disorder due to AUTS2 deficiency
RS749437705 Health Risk Conflicting classifications of pathogenicity
RS749784668 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Autism spectrum disorder due to AUTS2 deficiency, Inborn genetic diseases
RS750630131 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
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