TRAPPC6B Chromosome 14

Trafficking protein particle complex subunit 6B
7 variants 7 Health Risk

Upload your DNA to see your personal genotypes for variants in TRAPPC6B.

What This Gene Does
TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport (Kummel et al., 2005 [PubMed 16025134]).[supplied by OMIM, Mar 2008]
Gene Info
Gene Group
Trafficking protein particle complex subunits
Locus Type
gene with protein product
Location
14q21.1
Ensembl
ENSG00000182400
Associated Conditions (7)
TRAPPC6B-related disorder
Neurodevelopmental disorder with microcephaly
epilepsy
and brain atrophy
Colorectal cancer
TRAPPC6B-related neurodevelopmental disorder
Inborn genetic diseases
Key Variants
All Variants (7)
RSID Category Clinical Significance Conditions
RS2053152483 Health Risk Likely pathogenic TRAPPC6B-related disorder, TRAPPC6B-related disorder
RS758863393 Health Risk Likely pathogenic Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy
RS1347223331 Health Risk Pathogenic Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy
RS377626365 Health Risk Pathogenic Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy
RS750417849 Health Risk Pathogenic
RS761878844 Health Risk Pathogenic Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy
RS1171802070 Health Risk Pathogenic/Likely pathogenic TRAPPC6B-related neurodevelopmental disorder, Neurodevelopmental disorder with microcephaly, epilepsy
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