ARMC9 Chromosome 2

Armadillo repeat containing 9
44 variants 44 Health Risk

Upload your DNA to see your personal genotypes for variants in ARMC9.

What This Gene Does
Predicted to be involved in cilium assembly and positive regulation of smoothened signaling pathway. Located in centriole and ciliary basal body. Implicated in Joubert syndrome 30. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Armadillo repeat containing|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
2q37.1
Ensembl
ENSG00000135931
Associated Conditions (10)
ARMC9-related Joubert syndrome
Joubert syndrome
Joubert syndrome 30
Inborn genetic diseases
Corpus callosum
agenesis of
Diabetes mellitus
ARMC9-related disorder
Dandy-Walker syndrome
Malignant tumor of urinary bladder
Key Variants
All Variants (44)
RSID Category Clinical Significance Conditions
RS1114167447 Health Risk Conflicting classifications of pathogenicity ARMC9-related Joubert syndrome, Joubert syndrome, Joubert syndrome 30
RS138555701 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS201590882 Health Risk Conflicting classifications of pathogenicity Corpus callosum, agenesis of, Diabetes mellitus
RS201901213 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS202164814 Health Risk Conflicting classifications of pathogenicity ARMC9-related disorder, ARMC9-related disorder
RS2045539003 Health Risk Conflicting classifications of pathogenicity Joubert syndrome 30, Joubert syndrome 30
RS564939247 Health Risk Conflicting classifications of pathogenicity
RS750247691 Health Risk Conflicting classifications of pathogenicity ARMC9-related Joubert syndrome, Joubert syndrome 30, Joubert syndrome
RS752980410 Health Risk Conflicting classifications of pathogenicity Joubert syndrome 30, Joubert syndrome 30
RS769363225 Health Risk Conflicting classifications of pathogenicity Inborn genetic diseases, Inborn genetic diseases
RS1190417376 Health Risk Likely pathogenic
RS1220581324 Health Risk Likely pathogenic
RS1232994809 Health Risk Likely pathogenic
RS1248147660 Health Risk Likely pathogenic Joubert syndrome 30, Joubert syndrome 30
RS1574742486 Health Risk Likely pathogenic
RS201514487 Health Risk Likely pathogenic
RS2040982837 Health Risk Likely pathogenic
RS2469737879 Health Risk Likely pathogenic
RS2469747764 Health Risk Likely pathogenic
RS375762122 Health Risk Likely pathogenic
RS753730553 Health Risk Likely pathogenic
RS756655815 Health Risk Likely pathogenic
RS757763630 Health Risk Likely pathogenic
RS780265931 Health Risk Likely pathogenic ARMC9-related Joubert syndrome, Joubert syndrome, Dandy-Walker syndrome
RS781417301 Health Risk Likely pathogenic
RS1189780573 Health Risk Pathogenic Malignant tumor of urinary bladder, Malignant tumor of urinary bladder
RS1330612935 Health Risk Pathogenic Joubert syndrome 30, Joubert syndrome 30
RS1331571804 Health Risk Pathogenic Joubert syndrome 30, Joubert syndrome 30
RS1346443930 Health Risk Pathogenic
RS2039791235 Health Risk Pathogenic
RS2125334326 Health Risk Pathogenic
RS2125446588 Health Risk Pathogenic
RS2469664049 Health Risk Pathogenic
RS2469792629 Health Risk Pathogenic
RS2469837328 Health Risk Pathogenic
RS372770167 Health Risk Pathogenic ARMC9-related Joubert syndrome, Joubert syndrome 30, Joubert syndrome
RS754385274 Health Risk Pathogenic Joubert syndrome 30, Joubert syndrome 30
RS757131811 Health Risk Pathogenic
RS763539113 Health Risk Pathogenic
RS1114167448 Health Risk Pathogenic/Likely pathogenic ARMC9-related Joubert syndrome, Joubert syndrome 30, Joubert syndrome
RS1114167449 Health Risk Pathogenic/Likely pathogenic ARMC9-related Joubert syndrome, Joubert syndrome 30, Joubert syndrome
RS753432312 Health Risk Pathogenic/Likely pathogenic ARMC9-related Joubert syndrome, Joubert syndrome 30, Joubert syndrome
RS759799287 Health Risk Pathogenic/Likely pathogenic ARMC9-related Joubert syndrome, Joubert syndrome 30, Joubert syndrome
RS766572502 Health Risk Pathogenic/Likely pathogenic Joubert syndrome 30, Joubert syndrome 30
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