| RS750134026 |
TJP2
|
Health Risk |
Conflicting classifications of pathogenicity |
TJP2-related disorder, TJP2-related disorder |
| RS750135817 |
IFT43
|
Health Risk |
Conflicting classifications of pathogenicity |
Cranioectodermal dysplasia 3, Short-rib thoracic dysplasia 18 with polydactyly |
| RS750136163 |
DRC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 21 |
| RS750136202 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Alstrom syndrome |
| RS750136284 |
RB1
|
Health Risk |
Likely pathogenic |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS750136965 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS750138232 |
TUBGCP6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750138489 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Inborn genetic diseases |
| RS750138587 |
SELENON
|
Health Risk |
Conflicting classifications of pathogenicity |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS750141088 |
NSUN2
|
Health Risk |
Pathogenic |
— |
| RS750141316 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, RYR1-related disorder |
| RS750143580 |
ANK2
|
Health Risk |
Pathogenic |
— |
| RS750144413 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS750146549 |
BBS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 2 |
| RS750146750 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750146811 |
FLCN
|
Health Risk |
Pathogenic |
Familial spontaneous pneumothorax, Birt-Hogg-Dube syndrome |
| RS750147338 |
PDE6B
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS750147672 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS750147891 |
G6PC1
|
Health Risk |
Pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS750150415 |
MLYCD
|
Health Risk |
Pathogenic |
Deficiency of malonyl-CoA decarboxylase, Deficiency of malonyl-CoA decarboxylase |
| RS750151209 |
CERKL
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinitis pigmentosa 26 |
| RS750151535 |
PEX2
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder 5A (Zellweger), Peroxisome biogenesis disorder 5A (Zellweger) |
| RS750152844 |
TPM3
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy 4B, autosomal recessive |
| RS750153629 |
CEACAM16
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS750153731 |
COL7A1
|
Health Risk |
Likely pathogenic |
— |
| RS750154146 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Wilson disease |
| RS750155092 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS750156215 |
CPOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary coproporphyria, Hereditary coproporphyria |
| RS750156561 |
DNHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Male infertility with spermatogenesis disorder, Male infertility with spermatogenesis disorder |
| RS750157176 |
SMPD1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type A |
| RS750157767 |
CTSC
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Haim-Munk syndrome |
| RS750158756 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KBG syndrome |
| RS750159428 |
NEK1
|
Health Risk |
Pathogenic |
Amyotrophic lateral sclerosis, susceptibility to |
| RS750159671 |
GTF3C1
|
Health Risk |
Likely pathogenic |
Esophageal atresia/tracheoesophageal fistula, Esophageal atresia/tracheoesophageal fistula |
| RS750159744 |
CASQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Conduction disorder of the heart, Cardiovascular phenotype |
| RS750159862 |
ESCO2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, ESCO2-related disorder |
| RS750161314 |
MBD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750162087 |
CRB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750162094 |
CLN8
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis 8 northern epilepsy variant |
| RS750162817 |
FZD5
|
Health Risk |
Pathogenic |
Microphthalmia/coloboma 11, Microphthalmia/coloboma 11 |
| RS750163692 |
DEPDC5
|
Health Risk |
Pathogenic |
— |
| RS750165040 |
NRXN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins-like syndrome 2, Inborn genetic diseases |
| RS750166500 |
NTHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS750166986 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS750168062 |
NTRK1
|
Health Risk |
Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS750168369 |
ANO6
|
Health Risk |
Likely pathogenic |
SCOTT SYNDROME, SCOTT SYNDROME |
| RS750169840 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS750169914 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS750170007 |
MCOLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type IV, Retinal dystrophy |
| RS750170064 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, SCN8A-related disorder |
| RS750170870 |
ASXL1
|
Health Risk |
Pathogenic |
Bohring-Opitz syndrome, Bohring-Opitz syndrome |
| RS750172128 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1G |
| RS750173113 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrochondrogenesis 2, Autosomal recessive nonsyndromic hearing loss 53 |
| RS750174107 |
CACNA1G
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750174170 |
TSC2
|
Health Risk |
Pathogenic |
Tuberous sclerosis 2, Tuberous sclerosis 2 |
| RS750174638 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile hypophosphatasia, Adult hypophosphatasia |
| RS750174880 |
APC
|
Health Risk |
Likely pathogenic |
Ovarian cancer, Ovarian cancer |
| RS750174953 |
CHRND
|
Health Risk |
Pathogenic |
Lethal multiple pterygium syndrome, Lethal multiple pterygium syndrome |
| RS750175032 |
BCHE
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of butyrylcholinesterase, Inborn genetic diseases |
| RS750176716 |
FKTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A |
| RS750176752 |
DSG2
|
Health Risk |
Pathogenic |
Arrhythmogenic right ventricular dysplasia 10, Arrhythmogenic right ventricular dysplasia 10 |
| RS750176911 |
AGRN
|
Health Risk |
Likely pathogenic |
— |
| RS750177565 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
FLNB-Related Spectrum Disorders, Inborn genetic diseases |
| RS750178517 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to CREBBP mutations, Menke-Hennekam syndrome 1 |
| RS750178720 |
SLC34A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease |
| RS750179985 |
MAN2B1
|
Health Risk |
Pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS750180293 |
UROS
|
Health Risk |
Likely pathogenic |
Cutaneous porphyria, Cutaneous porphyria |
| RS750180579 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS750180668 |
CLCC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 32, Retinal dystrophy |
| RS750181262 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS750182587 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS750183691 |
ARL13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 8, Joubert syndrome 8 |
| RS750183985 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial meningioma |
| RS750184195 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS750185328 |
FAM161A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 28, Retinitis pigmentosa 28 |
| RS750185470 |
OPA1
|
Health Risk |
Likely pathogenic |
Autosomal dominant optic atrophy classic form, Autosomal dominant optic atrophy classic form |
| RS750185673 |
BBS12
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 12 |
| RS750185897 |
STX1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy with febrile seizures plus, type 9 |
| RS750185991 |
PLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Angioedema, hereditary |
| RS750187574 |
SMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type B |
| RS750187920 |
OTOF
|
Health Risk |
Pathogenic |
— |
| RS750188782 |
GJB2
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 1A, 7 conditions |
| RS750189082 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS750189181 |
ETFDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS750189238 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Autosomal dominant Alport syndrome |
| RS750190287 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS750190755 |
WNT10A
|
Health Risk |
Pathogenic |
Tooth agenesis, selective |
| RS750190975 |
CNNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750191719 |
CPT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine palmitoyltransferase II deficiency, Inborn genetic diseases |
| RS750193844 |
MYL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 10, MYL2-related disorder |
| RS750194090 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS750194822 |
PAX5
|
Health Risk |
Likely pathogenic |
Acute lymphoid leukemia, Acute lymphoid leukemia |
| RS750195040 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2K, Walker-Warburg congenital muscular dystrophy |
| RS750195683 |
PYGM
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease, type V |
| RS750195772 |
ATP2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brody myopathy, Brody myopathy |
| RS750195919 |
ACAT1
|
Health Risk |
Likely pathogenic |
Deficiency of acetyl-CoA acetyltransferase, Deficiency of acetyl-CoA acetyltransferase |
| RS75019736 |
CHRNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 4C, Congenital myasthenic syndrome 2A |
| RS750197808 |
PTCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750198250 |
FA2H
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia 35 |
| RS750199580 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |