CEACAM16 Chromosome 19
CEA cell adhesion molecule 16, tectorial membrane component
Upload your DNA to see your personal genotypes for variants in CEACAM16.
What This Gene Does
The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non-syndromic autosomal dominant hearing loss. [provided by RefSeq, May 2012]
Gene Info
Gene Group
"V-set domain containing|CEA cell adhesion molecule family"
Locus Type
gene with protein product
Location
19q13.31-q13.32
Ensembl
ENSG00000213892
Associated Conditions (8)
Inborn genetic diseases
CEACAM16-related disorder
Autosomal dominant nonsyndromic hearing loss 4B
Nonsyndromic genetic hearing loss
Hearing loss
autosomal recessive 113
Ear malformation
Rare genetic deafness
Key Variants
RS187740201
Conflicting classifications of pathogenicity
Health Risk
RS1948141206
Conflicting classifications of pathogenicity
Health Risk
RS199924613
Conflicting classifications of pathogenicity
Health Risk
RS200295094
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS200297676
Conflicting classifications of pathogenicity
Inborn genetic diseases, CEACAM16-related disorder, Inborn genetic diseases
Health Risk
RS201188632
Conflicting classifications of pathogenicity
Health Risk
RS367891074
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS370890913
Conflicting classifications of pathogenicity
Autosomal dominant nonsyndromic hearing loss 4B, CEACAM16-related disorder, Autosomal dominant nonsyndromic hearing loss 4B
Health Risk
RS373050209
Conflicting classifications of pathogenicity
Health Risk
RS373864861
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
RS375722926
Conflicting classifications of pathogenicity
Health Risk
RS377750953
Conflicting classifications of pathogenicity
Inborn genetic diseases, Inborn genetic diseases
Health Risk
All Variants (35)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS187740201 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1948141206 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS199924613 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS200295094 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS200297676 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, CEACAM16-related disorder, Inborn genetic diseases |
| RS201188632 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS367891074 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS370890913 | Health Risk | Conflicting classifications of pathogenicity | Autosomal dominant nonsyndromic hearing loss 4B, CEACAM16-related disorder, Autosomal dominant nonsyndromic hearing loss 4B |
| RS373050209 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS373864861 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS375722926 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS377750953 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS577629047 | Health Risk | Conflicting classifications of pathogenicity | Nonsyndromic genetic hearing loss, Nonsyndromic genetic hearing loss |
| RS577689341 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS61729706 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS746164064 | Health Risk | Conflicting classifications of pathogenicity | Nonsyndromic genetic hearing loss, Hearing loss, autosomal recessive 113 |
| RS746541677 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS747360355 | Health Risk | Conflicting classifications of pathogenicity | Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS750153629 | Health Risk | Conflicting classifications of pathogenicity | Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS754040589 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS756280582 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS762367899 | Health Risk | Conflicting classifications of pathogenicity | Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS777655944 | Health Risk | Conflicting classifications of pathogenicity | Hearing loss, autosomal recessive 113, Inborn genetic diseases |
| RS780034057 | Health Risk | Conflicting classifications of pathogenicity | Inborn genetic diseases, Inborn genetic diseases |
| RS909124308 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS1198256157 | Health Risk | Likely pathogenic | Hearing loss, autosomal recessive 113, Hearing loss |
| RS1599814534 | Health Risk | Likely pathogenic | Nonsyndromic genetic hearing loss, Nonsyndromic genetic hearing loss |
| RS2122194539 | Health Risk | Likely pathogenic | Ear malformation, Ear malformation |
| RS755154488 | Health Risk | Likely pathogenic | Rare genetic deafness, Rare genetic deafness |
| RS1347137461 | Health Risk | Pathogenic | Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS1568528171 | Health Risk | Pathogenic | Hearing loss, autosomal recessive 113, Hearing loss |
| RS2513589785 | Health Risk | Pathogenic | — |
| RS387907149 | Health Risk | Pathogenic | Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |
| RS754747851 | Health Risk | Pathogenic | — |
| RS876661405 | Health Risk | Pathogenic | Autosomal dominant nonsyndromic hearing loss 4B, Autosomal dominant nonsyndromic hearing loss 4B |