| RS749946303 |
SLC29A3
|
Health Risk |
Pathogenic |
H syndrome, H syndrome |
| RS749947335 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749947672 |
RAB11B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749947894 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749948143 |
KIF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Acrocallosal syndrome, Inborn genetic diseases |
| RS749948570 |
ASCC3
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal recessive 81 |
| RS749950017 |
TMPRSS15
|
Health Risk |
Pathogenic/Likely pathogenic |
Enterokinase deficiency, Enterokinase deficiency |
| RS749951287 |
CCDC78
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myopathy with internal nuclei and atypical cores, Congenital myopathy with internal nuclei and atypical cores |
| RS749951528 |
GABRG2
|
Health Risk |
Pathogenic |
Febrile seizures, familial |
| RS749951964 |
LEMD3
|
Health Risk |
Pathogenic |
— |
| RS749952316 |
GNPTG
|
Health Risk |
Likely pathogenic |
GNPTG-mucolipidosis, GNPTG-mucolipidosis |
| RS749952755 |
NPR2
|
Health Risk |
Pathogenic |
Acromesomelic dysplasia 1, Maroteaux type |
| RS749953234 |
KIF26B
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Autosomal dominant cerebellar ataxia |
| RS749954063 |
MARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe early-onset pulmonary alveolar proteinosis due to MARS deficiency, Charcot-Marie-Tooth disease axonal type 2U |
| RS749956288 |
ADGRV1
|
Health Risk |
Pathogenic |
Usher syndrome, Usher syndrome |
| RS749956542 |
PEX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 5A (Zellweger), Peroxisome biogenesis disorder 5B |
| RS749956849 |
IFNGR1
|
Health Risk |
Pathogenic |
Immunodeficiency 27A, Inherited Immunodeficiency Diseases |
| RS749959056 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS749959440 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS749960559 |
MYOC
|
Health Risk |
Likely pathogenic |
Open-angle glaucoma, Open-angle glaucoma |
| RS749961187 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS749961489 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS749963147 |
SH3TC2
|
Health Risk |
Pathogenic |
— |
| RS749963273 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, Cystic fibrosis |
| RS749963436 |
CHEK2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS749963653 |
HSPB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS749965480 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spondylocarpotarsal synostosis syndrome |
| RS749965674 |
STXBP1
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS749965891 |
CACNA2D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS749966284 |
PLA2G6
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile neuroaxonal dystrophy, PLA2G6-associated neurodegeneration |
| RS749966973 |
TMEM147
|
Health Risk |
Pathogenic/Likely pathogenic |
Poor speech, Severe intellectual disability |
| RS749968109 |
RFT1
|
Health Risk |
Likely pathogenic |
RFT1-congenital disorder of glycosylation, RFT1-congenital disorder of glycosylation |
| RS749969667 |
CHD2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 94, CHD2-related disorder |
| RS749969789 |
FERRY3
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, autosomal recessive 66 |
| RS749970078 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
ARID1A-related disorder, ARID1A-related disorder |
| RS749973572 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS749973847 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS749974211 |
LARGE1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy type B6, Muscular dystrophy-dystroglycanopathy type B6 |
| RS749974697 |
BBS9
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome |
| RS749974929 |
COL6A2
|
Health Risk |
Pathogenic |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1B |
| RS749975104 |
UGDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS749976222 |
PIEZO1
|
Health Risk |
Likely pathogenic |
Lymphatic malformation 6, Lymphatic malformation 6 |
| RS749976725 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, EHMT1-related disorder |
| RS749978235 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS749979249 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
Menke-Hennekam syndrome 2, Rubinstein-Taybi syndrome due to CREBBP mutations |
| RS749979474 |
TYR
|
Health Risk |
Pathogenic/Likely pathogenic |
Albinism, Oculocutaneous albinism type 1A |
| RS749979841 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS749980248 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749980306 |
GLB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile GM1 gangliosidosis, GM1 gangliosidosis type 2 |
| RS749980410 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS749980674 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS749980719 |
DNAH5
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS749980792 |
POMK
|
Health Risk |
Pathogenic/Likely pathogenic |
Limb-girdle muscular dystrophy due to POMK deficiency, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS749980819 |
SLC5A6
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodegeneration, infantile-onset |
| RS749981093 |
GLDC
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy |
| RS749981979 |
GALNT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS749982150 |
ADGRV1
|
Health Risk |
Likely pathogenic |
Febrile seizures, familial |
| RS749983428 |
BBS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 2, Bardet-Biedl syndrome |
| RS749985039 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS749986676 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS749987061 |
COLEC10
|
Health Risk |
Pathogenic |
3MC syndrome 3, 3MC syndrome 3 |
| RS749987648 |
RPGRIP1L
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS749988580 |
AIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS749988739 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS749989499 |
ALPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Decreased circulating alkaline phosphatase activity, Adult hypophosphatasia |
| RS749989641 |
ARSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS749990018 |
CNGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS749991162 |
HARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 3B, Usher syndrome type 3B |
| RS749992393 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS749992643 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS749993404 |
ATL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 3A, Inborn genetic diseases |
| RS749993527 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS749994173 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Charcot-Marie-Tooth disease dominant intermediate B |
| RS749994791 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 16 |
| RS749995118 |
CHRNG
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive multiple pterygium syndrome, Lethal multiple pterygium syndrome |
| RS74999515 |
ORC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Meier-Gorlin syndrome 3, Meier-Gorlin syndrome 3 |
| RS749995320 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS749995448 |
GRIK2
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 6 |
| RS749995672 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia |
| RS749996046 |
NEU1
|
Health Risk |
Pathogenic/Likely pathogenic |
Sialidosis, Sialidosis |
| RS749997451 |
NRROS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749998722 |
VPS13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750000204 |
KCNQ5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS750000952 |
PMP22
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, type I |
| RS750001158 |
MYPN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1KK |
| RS750003253 |
FANCC
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS750003586 |
SLC25A3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS750003804 |
VPS13B
|
Health Risk |
Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS750003992 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS750004710 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS750005344 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS750005711 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 64 |
| RS750005732 |
ARSA
|
Health Risk |
Conflicting classifications of pathogenicity |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS750005846 |
WNT1
|
Health Risk |
Likely pathogenic |
WNT1-related disorder, WNT1-related disorder |
| RS750006303 |
CPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
CPS1-related disorder, Congenital hyperammonemia |
| RS750007670 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS750008778 |
DOCK11
|
Health Risk |
Likely pathogenic |
DOCK11 deficiency, Autoinflammatory disease |
| RS750009006 |
PCDH15
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Usher syndrome type 1D |
| RS750010018 |
ALPK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS750010764 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |