| RS749875409 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749875462 |
CCDC183
|
Health Risk |
Likely pathogenic |
Essential tremor, Essential tremor |
| RS749875940 |
PCCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, Propionic acidemia |
| RS749876066 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS749876595 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS749876758 |
MOCS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749877603 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS749878139 |
ACADSB
|
Health Risk |
Pathogenic |
Deficiency of 2-methylbutyryl-CoA dehydrogenase, Deficiency of 2-methylbutyryl-CoA dehydrogenase |
| RS749878552 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Patterned macular dystrophy 2 |
| RS749879166 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS749880846 |
SPTA1
|
Health Risk |
Likely pathogenic |
— |
| RS749882600 |
GLDC
|
Health Risk |
Pathogenic |
Glycine encephalopathy, Glycine encephalopathy 1 |
| RS749883566 |
CEP250
|
Health Risk |
Pathogenic/Likely pathogenic |
Cone-rod dystrophy and hearing loss 2, Cone-rod dystrophy and hearing loss 2 |
| RS749884609 |
PCDH15
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 1F, Usher syndrome type 1D |
| RS749886570 |
WFS1
|
Health Risk |
Likely pathogenic |
Cataract 41, Cataract 41 |
| RS749888012 |
TARS1
|
Health Risk |
Pathogenic |
Trichothiodystrophy 7, nonphotosensitive |
| RS749888464 |
COL9A2
|
Health Risk |
Pathogenic |
— |
| RS74988902 |
ITGA2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Glanzmann thrombasthenia, ITGA2B-related disorder |
| RS749889050 |
USH2A
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 39, Usher syndrome type 2A |
| RS749889670 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS749890533 |
BSCL2
|
Health Risk |
Likely pathogenic |
Congenital generalized lipodystrophy type 2, Charcot-Marie-Tooth disease type 2 |
| RS749890642 |
TNXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome due to tenascin-X deficiency, Cardiovascular phenotype |
| RS749890843 |
TIMP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Sorsby fundus dystrophy, Sorsby fundus dystrophy |
| RS749891007 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS749891873 |
PLEKHG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS749891883 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS749893268 |
IRF2BPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with regression, abnormal movements |
| RS749893889 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS749895437 |
PIGT
|
Health Risk |
Pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 3, Multiple congenital anomalies-hypotonia-seizures syndrome 3 |
| RS749895492 |
TRMU
|
Health Risk |
Pathogenic/Likely pathogenic |
Aminoglycoside-induced deafness, Aminoglycoside-induced deafness |
| RS749895856 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
7 conditions, Carnitine palmitoyltransferase II deficiency |
| RS749896277 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS749896579 |
NR5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Premature ovarian failure, Premature ovarian failure |
| RS749897277 |
ATL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS749897373 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 10, Cardiomyopathy |
| RS749899018 |
POGZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome, Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome |
| RS749899964 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Hematuria |
| RS749899995 |
HOGA1
|
Health Risk |
Pathogenic |
— |
| RS749900784 |
GATA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypoparathyroidism, deafness |
| RS749901317 |
CEP152
|
Health Risk |
Pathogenic |
— |
| RS749901648 |
SOX11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Coffin-Siris syndrome |
| RS749903004 |
PDHA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyruvate dehydrogenase E1-alpha deficiency, Inborn genetic diseases |
| RS749903532 |
NLRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing loss, autosomal dominant 34 |
| RS749903604 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS749903718 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome |
| RS749907917 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS749908882 |
NTHL1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial adenomatous polyposis 3, Hereditary cancer-predisposing syndrome |
| RS749908889 |
PCCB
|
Health Risk |
Pathogenic |
Propionic acidemia, Propionic acidemia |
| RS749909863 |
EYS
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa 25 |
| RS749910508 |
WHRN
|
Health Risk |
Likely pathogenic |
Hepatocellular carcinoma, Hepatocellular carcinoma |
| RS749911553 |
MPI
|
Health Risk |
Pathogenic/Likely pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS749912295 |
OTOA
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749912939 |
EARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fetal akinesia deformation sequence 1, Arthrogryposis multiplex congenita |
| RS749913059 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Medulloblastoma, Gorlin syndrome |
| RS749913156 |
GOT1
|
Health Risk |
Pathogenic |
ASPARTATE AMINOTRANSFERASE, SERUM LEVEL OF |
| RS749913488 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS749914804 |
MCOLN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Mucolipidosis type IV |
| RS749916100 |
XPNPEP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis-like nephropathy 1, Nephronophthisis-like nephropathy 1 |
| RS749917447 |
CEP164
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis 15, Inborn genetic diseases |
| RS749918007 |
ASXL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749920996 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Inborn genetic diseases |
| RS749921338 |
PLOD3
|
Health Risk |
Pathogenic |
Bone fragility with contractures, arterial rupture |
| RS749921940 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS749922503 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS749922511 |
PYGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type VI |
| RS749922789 |
MSTO1
|
Health Risk |
Likely pathogenic |
Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome, Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome |
| RS749925817 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS749925915 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS749926328 |
CDHR1
|
Health Risk |
Pathogenic |
— |
| RS749926976 |
DNAH11
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS749927550 |
EGFR
|
Health Risk |
Conflicting classifications of pathogenicity |
EGFR-related lung cancer, Neoplasm |
| RS749927908 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS749929221 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS749929239 |
ETFA
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple acyl-CoA dehydrogenase deficiency, Glutaric acidemia type 2A |
| RS749929790 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 4, Hereditary cancer-predisposing syndrome |
| RS749930261 |
TRPM1
|
Health Risk |
Pathogenic |
Retinal dystrophy, Congenital stationary night blindness 1C |
| RS749930577 |
RYR2
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS749930791 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS749931257 |
ATP2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brody myopathy, Brody myopathy |
| RS749931280 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Dilated cardiomyopathy 1G |
| RS749931330 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS749934202 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS749935207 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 8 |
| RS74993523 |
XYLT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Desbuquois dysplasia 1, Inborn genetic diseases |
| RS749935719 |
ZBTB7A
|
Health Risk |
Pathogenic |
Macrocephaly, neurodevelopmental delay |
| RS749936057 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS749937461 |
DZIP1L
|
Health Risk |
Pathogenic |
— |
| RS749937487 |
EPM2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Inborn genetic diseases |
| RS749939097 |
SRCAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Floating-Harbor syndrome, Developmental delay |
| RS749939383 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS749940464 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS749942048 |
EIF2B4
|
Health Risk |
Likely pathogenic |
— |
| RS749942439 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS749942462 |
ARFGEF1
|
Health Risk |
Pathogenic |
Developmental delay, impaired speech |
| RS749942977 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS749943475 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS749943854 |
KRT4
|
Health Risk |
Conflicting classifications of pathogenicity |
White sponge nevus 1, Inborn genetic diseases |
| RS749944766 |
SFXN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS749946056 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Congenital heart disease |
| RS749946230 |
GABRG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 74 |