| RS759523751 |
MYO15A
|
Health Risk |
Pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 3 |
| RS759523949 |
AHI1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome |
| RS759524388 |
HFE
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary hemochromatosis, Hemochromatosis type 1 |
| RS759524596 |
NONO
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759524625 |
DYRK1A
|
Health Risk |
Conflicting classifications of pathogenicity |
DYRK1A-related intellectual disability syndrome, DYRK1A-related intellectual disability syndrome |
| RS759525338 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS759528091 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS759528128 |
B4GALNT1
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 26, Hereditary spastic paraplegia 26 |
| RS759528809 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS759530635 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759530743 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS759531099 |
TFRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759531544 |
CASZ1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759531782 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy 5, Developmental and epileptic encephalopathy |
| RS759531964 |
SHQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with dystonia and seizures, Neurodevelopmental disorder with dystonia and seizures |
| RS759532318 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS759532553 |
LARS2
|
Health Risk |
Pathogenic |
LARS2-Related Disorders, LARS2-Related Disorders |
| RS759536357 |
VPS13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS759536629 |
YY1
|
Health Risk |
Pathogenic/Likely pathogenic |
Gabriele de Vries syndrome, Gabriele de Vries syndrome |
| RS759536853 |
OPA3
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Methylglutaconic aciduria type 3, Optic atrophy 3 |
| RS759537444 |
IL10RA
|
Health Risk |
Pathogenic |
Inflammatory bowel disease 28, Inflammatory bowel disease 28 |
| RS759537735 |
LIFR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759537984 |
PDE6A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 43, Retinitis pigmentosa 43 |
| RS759538127 |
PSEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alzheimer disease 3, Frontotemporal dementia |
| RS759540763 |
SLC4A11
|
Health Risk |
Pathogenic/Likely pathogenic |
Corneal dystrophy, Fuchs endothelial |
| RS759540917 |
PIGQ
|
Health Risk |
Pathogenic |
Epilepsy, Epilepsy |
| RS759541634 |
RERE
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with or without anomalies of the brain, eye |
| RS759541820 |
PGAP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 4, Hyperphosphatasia with intellectual disability syndrome 4 |
| RS759542218 |
DPAGT1
|
Health Risk |
Likely pathogenic |
— |
| RS759542721 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS759542954 |
ABCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive inherited pseudoxanthoma elasticum, Pseudoxanthoma elasticum |
| RS759543703 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Simpson-Golabi-Behmel syndrome type 1 |
| RS759544193 |
F10
|
Health Risk |
Likely pathogenic |
— |
| RS759544282 |
LRRC51;LRTOMT
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 63, Autosomal recessive nonsyndromic hearing loss 63 |
| RS759545112 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 4 |
| RS759545618 |
MAP3K7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759545669 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS759547196 |
LMF1
|
Health Risk |
Pathogenic |
— |
| RS759549058 |
SLC12A3
|
Health Risk |
Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS759549373 |
DYNC2H1
|
Health Risk |
Likely pathogenic |
Asphyxiating thoracic dystrophy 3, Intellectual disability |
| RS759550730 |
SBF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4B2, Charcot-Marie-Tooth disease type 4 |
| RS759551120 |
ERCC5
|
Health Risk |
Likely pathogenic |
See cases, Cerebrooculofacioskeletal syndrome 3 |
| RS759551291 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS759551693 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS759552111 |
CAD
|
Health Risk |
Pathogenic |
— |
| RS759555122 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS759555645 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS759555791 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, LAMA2-related muscular dystrophy |
| RS759556319 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS759557020 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS759557055 |
PAX6
|
Health Risk |
Pathogenic |
Aniridia 1, Irido-corneo-trabecular dysgenesis |
| RS759559801 |
NPHS1
|
Health Risk |
Pathogenic |
— |
| RS759560622 |
DLL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndactyly, Spondylocostal dysostosis 1 |
| RS759560822 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS759561079 |
STAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
STAG1-related disorder, Congenital ocular coloboma |
| RS759561105 |
SNRPB
|
Health Risk |
Likely pathogenic |
— |
| RS759561106 |
SRD5A2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency, 3-Oxo-5 alpha-steroid delta 4-dehydrogenase deficiency |
| RS759561558 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS759561565 |
XPC
|
Health Risk |
Likely pathogenic |
Xeroderma pigmentosum, group C |
| RS759561852 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759562639 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759562755 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, SMARCAL1-related disorder |
| RS759563092 |
HIBCH
|
Health Risk |
Likely pathogenic |
3-hydroxyisobutyryl-CoA hydrolase deficiency, 3-hydroxyisobutyryl-CoA hydrolase deficiency |
| RS759563506 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS759563967 |
PDE6A
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinitis pigmentosa 43 |
| RS759567393 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS759568612 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS759568760 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS759568939 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS759568976 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS759569482 |
VCX3B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759572190 |
AGPS
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhizomelic chondrodysplasia punctata type 3, Inborn genetic diseases |
| RS759573423 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Endometrial carcinoma |
| RS759573888 |
GLDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycine encephalopathy, Glycine encephalopathy |
| RS759573909 |
GP1BA
|
Health Risk |
Likely pathogenic |
Bernard Soulier syndrome, Bernard-Soulier syndrome |
| RS759574062 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS759574423 |
TRPM4
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial heart block type IB, Cardiovascular phenotype |
| RS759576380 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS759576627 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759578199 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS759579036 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS759579169 |
MPI
|
Health Risk |
Pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS759579368 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Alport syndrome, Autosomal recessive Alport syndrome |
| RS759579664 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759579761 |
COL7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Epidermolysis bullosa dystrophica, 7 conditions |
| RS759579854 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS759580358 |
MICOS13
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759580516 |
CPLANE1
|
Health Risk |
Pathogenic |
— |
| RS759580799 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS759580965 |
SLC6A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperekplexia 3, Inborn genetic diseases |
| RS759581452 |
RYR3
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS759581547 |
CASP8
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune lymphoproliferative syndrome type 2B, Autoimmune lymphoproliferative syndrome type 2B |
| RS759581558 |
GAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Giant axonal neuropathy 1 |
| RS759581954 |
WFS1
|
Health Risk |
Likely pathogenic |
— |
| RS759582306 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS759582696 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Epilepsy |
| RS759583931 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759583948 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Alport syndrome |
| RS759583976 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS759584117 |
LHX3
|
Health Risk |
Conflicting classifications of pathogenicity |
Non-acquired combined pituitary hormone deficiency with spine abnormalities, Non-acquired combined pituitary hormone deficiency with spine abnormalities |