| RS759646328 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia 11 |
| RS759646439 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS759646708 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS759646819 |
NEU1
|
Health Risk |
Likely pathogenic |
— |
| RS759646845 |
DNAH1
|
Health Risk |
Pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS759647230 |
BMPR1A
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS759648976 |
TTC21B
|
Health Risk |
Likely pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS759649053 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 17, Joubert syndrome 17 |
| RS759649059 |
TNFRSF13B
|
Health Risk |
Pathogenic |
Immunodeficiency, common variable |
| RS759649136 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS759650325 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS759652500 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759653224 |
ALOX12B
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive congenital ichthyosis 2, Autosomal recessive congenital ichthyosis 2 |
| RS759653444 |
KDM3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759654665 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS759655692 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS759656065 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759656227 |
PIGG
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 53 |
| RS759656254 |
NLGN3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759656684 |
NDUFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759656981 |
HERC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759657187 |
STXBP2
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS759657964 |
PYGM
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type V |
| RS759658215 |
COQ9
|
Health Risk |
Pathogenic |
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome |
| RS759658629 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS759660507 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS759660796 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ventricular tachycardia, Arrhythmogenic right ventricular dysplasia 9 |
| RS759662469 |
IFT74
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Inborn genetic diseases |
| RS759662695 |
CRB1
|
Health Risk |
Pathogenic |
Early-onset retinal dystrophy, Leber congenital amaurosis 8 |
| RS759662717 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS759662786 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group C |
| RS759663463 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS759663956 |
MCPH1
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly 1, primary |
| RS759664259 |
TPP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronal ceroid lipofuscinosis, Juvenile neuronal ceroid lipofuscinosis |
| RS759665242 |
RMRP
|
Health Risk |
Likely pathogenic |
Metaphyseal chondrodysplasia, McKusick type |
| RS759665328 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759665341 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS759665516 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS759666274 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS759666789 |
CYP11B2
|
Health Risk |
Pathogenic |
— |
| RS759667201 |
RFXANK
|
Health Risk |
Pathogenic/Likely pathogenic |
MHC class II deficiency, MHC class II deficiency 2 |
| RS759667344 |
SLC4A11
|
Health Risk |
Pathogenic/Likely pathogenic |
Corneal dystrophy-perceptive deafness syndrome, Corneal dystrophy-perceptive deafness syndrome |
| RS759667494 |
LPIN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Majeed syndrome, Majeed syndrome |
| RS759668154 |
ADGRV1
|
Health Risk |
Pathogenic/Likely pathogenic |
Febrile seizures, familial |
| RS759668583 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS759668652 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS759669801 |
PNKD
|
Health Risk |
Conflicting classifications of pathogenicity |
Paroxysmal nonkinesigenic dyskinesia 1, Paroxysmal nonkinesigenic dyskinesia |
| RS759672616 |
ABCA4
|
Health Risk |
Pathogenic |
Severe early-childhood-onset retinal dystrophy, Retinal dystrophy |
| RS759673011 |
MPDZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759674249 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS759674700 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS759675006 |
CEP104
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal recessive 77 |
| RS759676430 |
CFI
|
Health Risk |
Pathogenic/Likely pathogenic/Pathogenic, low penetrance |
Atypical hemolytic-uremic syndrome, CFI-related disorder |
| RS759676621 |
BIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, centronuclear |
| RS759676847 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 5, Cardiomyopathy |
| RS759677822 |
PROS1
|
Health Risk |
Pathogenic |
Thrombophilia due to protein S deficiency, autosomal recessive |
| RS75967811 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Transitory neonatal diabetes mellitus, Maturity-onset diabetes of the young |
| RS759678346 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS759678509 |
BEST1
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitelliform macular dystrophy 2, Autosomal dominant vitreoretinochoroidopathy |
| RS759679443 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS759679579 |
SMAD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS759679732 |
BCHE
|
Health Risk |
Likely pathogenic |
Deficiency of butyrylcholinesterase, Deficiency of butyrylcholinesterase |
| RS759680369 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759680428 |
COG7
|
Health Risk |
Conflicting classifications of pathogenicity |
COG7 congenital disorder of glycosylation, COG7 congenital disorder of glycosylation |
| RS759680619 |
OBSCN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759680878 |
MRE11
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia-like disorder, Ataxia-telangiectasia-like disorder |
| RS759682922 |
BBS10
|
Health Risk |
Pathogenic |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS759683649 |
SLC26A4
|
Health Risk |
Pathogenic |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS759684383 |
TOGARAM1
|
Health Risk |
Pathogenic |
Joubert syndrome, Joubert syndrome 37 |
| RS759685032 |
WRN
|
Health Risk |
Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS759686216 |
FRMD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759686739 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Early-onset myopathy with fatal cardiomyopathy |
| RS759687021 |
COMP
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudoachondroplastic spondyloepiphyseal dysplasia syndrome, Multiple epiphyseal dysplasia type 1 |
| RS759687469 |
CAD
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 50 |
| RS759688621 |
ALMS1
|
Health Risk |
Pathogenic |
— |
| RS759689002 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS759689776 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS759690535 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS759692350 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS759692592 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome 4 |
| RS759692686 |
VPS41
|
Health Risk |
Likely pathogenic |
Spinocerebellar ataxia, autosomal recessive 29 |
| RS759692888 |
DIABLO
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759694252 |
SCN11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary sensory and autonomic neuropathy type 7, Familial episodic pain syndrome with predominantly lower limb involvement |
| RS759694605 |
FOXH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Holoprosencephaly sequence, Inborn genetic diseases |
| RS759694779 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS759696323 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS759698959 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS759699162 |
GLDC
|
Health Risk |
Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy |
| RS759699355 |
GALK1
|
Health Risk |
Pathogenic |
Deficiency of galactokinase, GALK1-related disorder |
| RS759701000 |
LRP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cenani-Lenz syndactyly syndrome, Congenital myasthenic syndrome 17 |
| RS759703047 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS759703272 |
PARK7
|
Health Risk |
Likely pathogenic |
— |
| RS759705666 |
INSR
|
Health Risk |
Conflicting classifications of pathogenicity |
Rabson-Mendenhall syndrome, Insulin-resistant diabetes mellitus AND acanthosis nigricans |
| RS759706198 |
SAMHD1
|
Health Risk |
Pathogenic |
Aicardi-Goutieres syndrome 5, Aicardi-Goutieres syndrome 5 |
| RS759706334 |
RORA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759706360 |
CHEK2
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS759707001 |
TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
Sarcotubular myopathy, Bardet-Biedl syndrome 11 |
| RS759707174 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS759707480 |
RP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, RP1-related disorder |
| RS759707498 |
GBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
GBE1-related disorder, Glycogen storage disease |