| RS759851475 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS759852661 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
PTEN hamartoma tumor syndrome, Hereditary cancer-predisposing syndrome |
| RS759852969 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759853433 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Alagille syndrome due to a JAG1 point mutation |
| RS759853904 |
AGRN
|
Health Risk |
Likely pathogenic |
Congenital myasthenic syndrome 8, Congenital myasthenic syndrome 8 |
| RS759853907 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
RINT1-related disorder, Infantile liver failure syndrome 3 |
| RS759856167 |
AHNAK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759856890 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS759857078 |
EARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759857680 |
MED12
|
Health Risk |
Conflicting classifications of pathogenicity |
FG syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS759857784 |
KLHL7
|
Health Risk |
Likely pathogenic |
— |
| RS759857993 |
PCSK1
|
Health Risk |
Conflicting classifications of pathogenicity |
PCSK1-related disorder, PCSK1-related disorder |
| RS759858754 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS759858813 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS759860918 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS759862062 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS759862377 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS759863454 |
XPNPEP3
|
Health Risk |
Pathogenic |
Nephronophthisis-like nephropathy 1, Nephronophthisis-like nephropathy 1 |
| RS759864013 |
PEX26
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 7A (Zellweger), Peroxisome biogenesis disorder 7B |
| RS759867905 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS759868546 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Colorectal cancer |
| RS75986913 |
MYO9A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759869189 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759869347 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 8 |
| RS759870594 |
MLH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS759873621 |
COL4A3
|
Health Risk |
Pathogenic |
Autosomal recessive Alport syndrome, Alport syndrome |
| RS759874172 |
COLQ
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 5, Congenital myasthenic syndrome 5 |
| RS759874504 |
MYORG
|
Health Risk |
Pathogenic |
— |
| RS759874793 |
ALDH3A2
|
Health Risk |
Likely pathogenic |
Sjögren-Larsson syndrome, Sjögren-Larsson syndrome |
| RS759875552 |
FKRP
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2I |
| RS759875729 |
GSR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759876062 |
OCA2
|
Health Risk |
Pathogenic/Likely pathogenic |
SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES |
| RS759876319 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS759877008 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS759878392 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS759878676 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759881074 |
CPLANE1
|
Health Risk |
Likely pathogenic |
Orofaciodigital syndrome type 6, Joubert syndrome 17 |
| RS759881199 |
TYRP1
|
Health Risk |
Pathogenic |
— |
| RS759881866 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS759883057 |
UNC93B1
|
Health Risk |
Pathogenic |
Herpes simplex encephalitis, susceptibility to |
| RS759883263 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Idiopathic Pulmonary Fibrosis |
| RS759883512 |
GPIHBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperlipoproteinemia, type 1D |
| RS759884526 |
GPD2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759885491 |
TNNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 5, Nemaline myopathy 5 |
| RS759886963 |
GYS2
|
Health Risk |
Likely pathogenic |
Glycogen storage disorder due to hepatic glycogen synthase deficiency, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS759887905 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHD7-related disorder |
| RS759888144 |
KIAA0586
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 14 with polydactyly, Joubert syndrome 23 |
| RS759888604 |
SUMF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Multiple sulfatase deficiency, Multiple sulfatase deficiency |
| RS759890035 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS759891490 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Familial hemophagocytic lymphohistiocytosis 3 |
| RS759892467 |
TBCK
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypotonia, infantile |
| RS759893630 |
HRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Costello syndrome, Intellectual disability |
| RS759895083 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS759896283 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Rhabdoid tumor predisposition syndrome 2, Hereditary cancer-predisposing syndrome |
| RS759896413 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral arteriopathy, autosomal dominant |
| RS759897255 |
KMT2E
|
Health Risk |
Pathogenic |
— |
| RS759898332 |
TPM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arthrogryposis, distal |
| RS759898401 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Saldino-Mainzer syndrome |
| RS759898408 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS759898765 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Usher syndrome type 2A |
| RS759899058 |
RINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759899153 |
FANCA
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS759899864 |
IFT27
|
Health Risk |
Conflicting classifications of pathogenicity |
IFT27-related disorder, Inborn genetic diseases |
| RS759900071 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group C, Fanconi anemia |
| RS759900272 |
KAT6A
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS759901142 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759901793 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS759904153 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS759904221 |
CPT1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 73, Hereditary spastic paraplegia 73 |
| RS759904861 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Primary ciliary dyskinesia |
| RS759905184 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS759905934 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS759907949 |
WASHC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 8, Ritscher-Schinzel syndrome |
| RS759908186 |
AKR1D1
|
Health Risk |
Likely pathogenic |
Congenital bile acid synthesis defect 2, Congenital bile acid synthesis defect 2 |
| RS759908203 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759909394 |
SUGCT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759909785 |
HPS4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS75991011 |
SMN1
|
Health Risk |
Pathogenic |
Werdnig-Hoffmann disease, Werdnig-Hoffmann disease |
| RS759910341 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Thymoma |
| RS759911602 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS759911990 |
COLQ
|
Health Risk |
Pathogenic |
Congenital myasthenic syndrome 5, Congenital myasthenic syndrome 5 |
| RS759912179 |
ANKZF1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759913385 |
PRF1
|
Health Risk |
Likely pathogenic |
Aplastic anemia, Familial hemophagocytic lymphohistiocytosis 2 |
| RS759913677 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
ARID1A-related disorder, Inborn genetic diseases |
| RS759913777 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS759913983 |
RRP8
|
Health Risk |
association |
Autism spectrum disorder, Autism spectrum disorder |
| RS759914132 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS759914921 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Inborn genetic diseases |
| RS759915989 |
MEI1
|
Health Risk |
Pathogenic |
Hydatidiform mole, recurrent |
| RS759916327 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS759916956 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS759917180 |
TCF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Agammaglobulinemia 8b, autosomal recessive |
| RS759917227 |
CEP152
|
Health Risk |
Pathogenic |
— |
| RS759917468 |
AXIN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Colorectal cancer, Oligodontia-cancer predisposition syndrome |
| RS75991777 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 1, Cardiovascular phenotype |
| RS759918327 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS759918870 |
COL6A1
|
Health Risk |
Pathogenic |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS759918881 |
PCNT
|
Health Risk |
Likely pathogenic |
— |
| RS759919085 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759921094 |
TUB
|
Health Risk |
Pathogenic |
— |