| RS760039339 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Schaaf-Yang syndrome, Inborn genetic diseases |
| RS760040029 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS760040426 |
DCDC2
|
Health Risk |
Pathogenic |
Nephronophthisis 19, Autosomal recessive nonsyndromic hearing loss 66 |
| RS760040495 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Early-onset myopathy with fatal cardiomyopathy |
| RS760040670 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS760041708 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS760041868 |
BMPER
|
Health Risk |
Conflicting classifications of pathogenicity |
Diaphanospondylodysostosis, Diaphanospondylodysostosis |
| RS760042062 |
PDE6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Congenital stationary night blindness autosomal dominant 2 |
| RS760043106 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Fraumeni syndrome, Lung adenocarcinoma |
| RS760043559 |
EVC
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS760044422 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Charcot-Marie-Tooth disease |
| RS760045017 |
CDK5RAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 3, primary |
| RS760045493 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS760048191 |
MSMO1
|
Health Risk |
Likely pathogenic |
Microcephaly-congenital cataract-psoriasiform dermatitis syndrome, Inborn genetic diseases |
| RS760049336 |
MFSD8
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronal ceroid lipofuscinosis 7, Macular dystrophy with central cone involvement |
| RS760049549 |
PLCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 3 |
| RS760051760 |
JAK3
|
Health Risk |
Pathogenic |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, Thyroid cancer |
| RS760051929 |
BCLAF1
|
Health Risk |
Pathogenic |
Pulmonary artery atresia, Pulmonary artery atresia |
| RS760052391 |
DOCK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 23 |
| RS760053992 |
OBSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760054945 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group D2, Fanconi anemia |
| RS760056670 |
PIK3CA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cowden syndrome, Cowden syndrome |
| RS760058702 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary breast ovarian cancer syndrome |
| RS760059077 |
POGZ
|
Health Risk |
association |
Autism spectrum disorder, Autism spectrum disorder |
| RS760059307 |
MPL
|
Health Risk |
Likely pathogenic |
Congenital amegakaryocytic thrombocytopenia, Congenital amegakaryocytic thrombocytopenia |
| RS760059747 |
DDX41
|
Health Risk |
Pathogenic/Likely pathogenic |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS760060777 |
EMC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebellar atrophy, visual impairment |
| RS760060843 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS760061071 |
STXBP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS760062120 |
ABCC8
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary hyperinsulinism, Diabetes mellitus |
| RS760063197 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica inversa |
| RS760063214 |
GAA
|
Health Risk |
Pathogenic |
Glycogen storage disease, type II |
| RS760063405 |
SELENON
|
Health Risk |
Pathogenic/Likely pathogenic |
Eichsfeld type congenital muscular dystrophy, Eichsfeld type congenital muscular dystrophy |
| RS760065045 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial melanoma, Hereditary cancer-predisposing syndrome |
| RS760065522 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS760065931 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Congenital contractural arachnodactyly |
| RS760066386 |
EVC2
|
Health Risk |
Likely pathogenic |
Ellis-van Creveld syndrome, Ellis-van Creveld syndrome |
| RS760066546 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760066611 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 12 |
| RS760066667 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760067070 |
ABRAXAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760068474 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS760069458 |
NOD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Regional enteritis, Blau syndrome |
| RS760069953 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Rare genetic deafness |
| RS760070332 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS760071332 |
POMT1
|
Health Risk |
Pathogenic |
Walker-Warburg congenital muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2K |
| RS760071472 |
HCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS760071561 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS760072286 |
YARS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760072343 |
AHNAK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760073103 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS760073211 |
C2CD3
|
Health Risk |
Pathogenic |
— |
| RS760074158 |
GP6
|
Health Risk |
Pathogenic/Likely pathogenic |
Platelet-type bleeding disorder 11, Platelet-type bleeding disorder 11 |
| RS760074335 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS760076679 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS760077598 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS760077781 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS760077981 |
GLDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycine encephalopathy, Glycine encephalopathy |
| RS760077990 |
SPINK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pancreatitis, Hereditary pancreatitis |
| RS760079000 |
HNF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cysts and diabetes syndrome, Type 2 diabetes mellitus |
| RS760079073 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS760079636 |
TGFBR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Loeys-Dietz syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS760080044 |
COQ4
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome, Inborn genetic diseases |
| RS760081421 |
LOXHD1
|
Health Risk |
Pathogenic |
— |
| RS760081465 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS760081822 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS760082356 |
CACNA1S
|
Health Risk |
Likely pathogenic |
Hypokalemic periodic paralysis, type 1 |
| RS760082702 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS760083496 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Gastric cancer |
| RS760083523 |
OPA3
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Methylglutaconic aciduria type 3, Optic atrophy 3 |
| RS760083976 |
LIFR
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS760084513 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS760084731 |
DCDC2
|
Health Risk |
Likely pathogenic |
Nephronophthisis 19, Nephronophthisis 19 |
| RS760085327 |
PAPSS2
|
Health Risk |
Pathogenic |
Spondyloepimetaphyseal dysplasia, PAPSS2 type |
| RS760088260 |
TAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760088331 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS760088579 |
SPTB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760089379 |
TSEN54
|
Health Risk |
Conflicting classifications of pathogenicity |
Pontoneocerebellar hypoplasia, Inborn genetic diseases |
| RS760090242 |
MYO15A
|
Health Risk |
Pathogenic |
MYO15A-related disorder, MYO15A-related disorder |
| RS760091174 |
C8A
|
Health Risk |
Likely pathogenic |
— |
| RS760093841 |
COL2A1
|
Health Risk |
Likely pathogenic |
Spondyloepiphyseal dysplasia, Stanescu type |
| RS760093872 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune interstitial lung disease-arthritis syndrome, Inborn genetic diseases |
| RS760094345 |
COL17A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Junctional epidermolysis bullosa, non-Herlitz type |
| RS760094988 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS760096507 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, ANK2-related disorder |
| RS760097427 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS760097703 |
IFT172
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS760098710 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS760099299 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS760099622 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS760100325 |
CRB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 8, Retinitis pigmentosa 12 |
| RS760100924 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS760100983 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Lynch syndrome 5, Hereditary cancer-predisposing syndrome |
| RS760101172 |
NAE1
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with dysmorphic facies and ischiopubic hypoplasia, Neurodevelopmental disorder with dysmorphic facies and ischiopubic hypoplasia |
| RS760101382 |
GAMT
|
Health Risk |
Likely pathogenic |
Cerebral creatine deficiency syndrome, Deficiency of guanidinoacetate methyltransferase |
| RS760101861 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1A |
| RS760102207 |
ABCA4
|
Health Risk |
Pathogenic |
— |
| RS760102500 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Nemaline myopathy 6 |
| RS760102576 |
ADA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of adenosine deaminase 2, Sneddon syndrome |
| RS760104150 |
POLH
|
Health Risk |
Likely pathogenic |
Xeroderma pigmentosum variant type, Xeroderma pigmentosum variant type |