| RS759982229 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Paramyotonia congenita of Von Eulenburg, Congenital myasthenic syndrome 16 |
| RS759982570 |
DNAJB6
|
Health Risk |
Pathogenic |
Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6), Abnormality of the musculature |
| RS759982943 |
G6PC1
|
Health Risk |
Likely pathogenic |
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA, Glycogen storage disease due to glucose-6-phosphatase deficiency type IA |
| RS759983332 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS759983785 |
PRF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 2, Familial hemophagocytic lymphohistiocytosis 2 |
| RS759985112 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759987183 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Spastic paraplegia |
| RS759987234 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS759987427 |
F9
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary factor IX deficiency disease, Thrombophilia |
| RS759987473 |
IGHMBP2
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2S, Autosomal recessive distal spinal muscular atrophy 1 |
| RS759988046 |
PIGV
|
Health Risk |
Likely pathogenic |
Hyperphosphatasia with intellectual disability syndrome 1, Hyperphosphatasia with intellectual disability syndrome 1 |
| RS759988398 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypocalciuric hypercalcemia, Autosomal dominant hypocalcemia 1 |
| RS759988845 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS759989401 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759989949 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS759989953 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS759990188 |
UBR1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759990189 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa pruriginosa, autosomal recessive |
| RS759990771 |
BMPR2
|
Health Risk |
Pathogenic |
Pulmonary hypertension, primary |
| RS759991375 |
SLC26A4
|
Health Risk |
Likely pathogenic |
— |
| RS759991844 |
DVL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759992526 |
KCNJ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 2, Inborn genetic diseases |
| RS759992645 |
SUOX
|
Health Risk |
Conflicting classifications of pathogenicity |
Sulfite oxidase deficiency, Sulfite oxidase deficiency |
| RS759993423 |
KCNJ10
|
Health Risk |
Conflicting classifications of pathogenicity |
EAST syndrome, Inborn genetic diseases |
| RS759993457 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, Inborn genetic diseases |
| RS759997079 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Mevalonic aciduria, Porokeratosis 3 |
| RS759997114 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Hereditary spastic paraplegia 39 |
| RS759997694 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Acute febrile neutrophilic dermatosis |
| RS759997772 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS759998177 |
MAP2K2
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS759998394 |
GLRA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hyperekplexia, Hereditary hyperekplexia |
| RS759998867 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Saldino-Mainzer syndrome |
| RS759998900 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Ehlers-Danlos syndrome |
| RS759998919 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-hypotonia-spasticity-sleep disorder syndrome, Inborn genetic diseases |
| RS760000075 |
TTI1
|
Health Risk |
Likely pathogenic |
Severe intellectual disability, Severe intellectual disability |
| RS760000110 |
CHM
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760001414 |
ATF6
|
Health Risk |
Pathogenic |
— |
| RS760001730 |
ZFYVE26
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 15, Cervical cancer |
| RS760001916 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS760003063 |
NAGA
|
Health Risk |
Conflicting classifications of pathogenicity |
Alpha-N-acetylgalactosaminidase deficiency type 1, Alpha-N-acetylgalactosaminidase deficiency type 2 |
| RS760003191 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS760003902 |
ITPA
|
Health Risk |
Pathogenic |
Inosine triphosphatase deficiency, Inosine triphosphatase deficiency |
| RS760004573 |
NPC1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type C1 |
| RS760004891 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Alagille syndrome due to a NOTCH2 point mutation |
| RS760005580 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS760006536 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS760006956 |
ABCA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Interstitial lung disease due to ABCA3 deficiency, Interstitial lung disease due to ABCA3 deficiency |
| RS760007187 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, Inborn genetic diseases |
| RS760007740 |
SYNE4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760007747 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760007799 |
KMT2D
|
Health Risk |
Pathogenic |
Kabuki syndrome, Kabuki syndrome |
| RS760008381 |
DLL1
|
Health Risk |
Pathogenic |
See cases, Neurodevelopmental disorder with nonspecific brain abnormalities and with or without seizures |
| RS760010021 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS760010175 |
RYR1
|
Health Risk |
Likely pathogenic |
— |
| RS760011180 |
MOCS1
|
Health Risk |
Pathogenic |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A |
| RS760011764 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS760012847 |
NDE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Lissencephaly 4, Lissencephaly 4 |
| RS760013326 |
INVS
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Infantile nephronophthisis |
| RS760014795 |
TTPA
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial isolated deficiency of vitamin E, Inborn genetic diseases |
| RS760015202 |
COG5
|
Health Risk |
Likely pathogenic |
— |
| RS760015622 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS760015626 |
KCNA5
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial fibrillation, familial |
| RS760017478 |
TH
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive DOPA responsive dystonia, Inborn genetic diseases |
| RS760017935 |
SP110
|
Health Risk |
Conflicting classifications of pathogenicity |
Hepatic veno-occlusive disease-immunodeficiency syndrome, Inborn genetic diseases |
| RS760019076 |
RELN
|
Health Risk |
Pathogenic |
9 conditions, 9 conditions |
| RS760021784 |
KARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760021808 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS760022693 |
PTPN23
|
Health Risk |
Conflicting classifications of pathogenicity |
Global developmental delay, Brain atrophy |
| RS760022829 |
CHRNE
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 4A, Congenital myasthenic syndrome 4B |
| RS760022956 |
TACR3
|
Health Risk |
Likely pathogenic |
Hypogonadotropic hypogonadism 11 with or without anosmia, TACR3-related disorder |
| RS760023025 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS760023084 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS760024638 |
TUBGCP6
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly and chorioretinopathy 1, Microcephaly and chorioretinopathy 1 |
| RS760024863 |
IL13RA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760025627 |
TPRN
|
Health Risk |
Pathogenic |
— |
| RS760026221 |
DNAH9
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital heart disease, Ciliary dyskinesia |
| RS760027420 |
ERCC6
|
Health Risk |
Pathogenic |
— |
| RS760027964 |
AIRE
|
Health Risk |
Conflicting classifications of pathogenicity |
Polyglandular autoimmune syndrome, type 1 |
| RS760028443 |
TRIP11
|
Health Risk |
Pathogenic |
Achondrogenesis, type IA |
| RS760029026 |
GEMIN5
|
Health Risk |
Likely pathogenic |
GEMIN5-related neurodevelopmental disorder, Inborn genetic diseases |
| RS760029045 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760029192 |
HLCS
|
Health Risk |
Likely pathogenic |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS760029254 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypophosphatasia, Adult hypophosphatasia |
| RS760030067 |
FDXR
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS760030699 |
MYO5B
|
Health Risk |
Pathogenic |
— |
| RS760031457 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital hypothyroidism, Thyroid dyshormonogenesis 6 |
| RS760031526 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS760032006 |
TP63
|
Health Risk |
Likely pathogenic |
— |
| RS760032797 |
CYP17A1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, Deficiency of steroid 17-alpha-monooxygenase |
| RS760033003 |
ANO5
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS760033566 |
PRKAR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carney complex, type 1 |
| RS760033609 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760033804 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Shprintzen-Goldberg syndrome |
| RS760034724 |
VPS13A
|
Health Risk |
Pathogenic |
— |
| RS760034947 |
TCTN2
|
Health Risk |
Pathogenic/Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS760036030 |
TCOF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Treacher Collins syndrome 1, Treacher Collins syndrome 1 |
| RS760037330 |
ANKRD11
|
Health Risk |
Likely pathogenic |
KBG syndrome, KBG syndrome |
| RS760037989 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS760038328 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS760038605 |
RACGAP1
|
Health Risk |
Pathogenic |
Anemia, congenital dyserythropoietic |