| RS759708484 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759708614 |
EXT1
|
Health Risk |
Pathogenic |
Multiple congenital exostosis, Multiple congenital exostosis |
| RS759709025 |
HKDC1
|
Health Risk |
Likely pathogenic |
Nonsyndromic cleft lip palate, Nonsyndromic cleft lip palate |
| RS759709365 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS759709450 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS759709467 |
CDK5RAP2
|
Health Risk |
Pathogenic |
Microcephaly 3, primary |
| RS759711668 |
ZNF341
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyper-IgE recurrent infection syndrome 3, autosomal recessive |
| RS759712763 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759712974 |
TRIP13
|
Health Risk |
Pathogenic |
Oocyte maturation defect 9, Oocyte maturation defect 9 |
| RS759713394 |
POU4F3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 15, Autosomal dominant nonsyndromic hearing loss 15 |
| RS75971351 |
UMPS
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary orotic aciduria, type 1 |
| RS759713604 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS75971372 |
FKTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1X, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS759714493 |
SHOC2
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS759714698 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS759715306 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759720450 |
DHCR7
|
Health Risk |
Pathogenic/Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS759722579 |
STAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mendelian susceptibility to mycobacterial diseases due to partial STAT1 deficiency, Autoimmune enteropathy and endocrinopathy - susceptibility to chronic infections syndrome |
| RS759724715 |
NT5C2
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 45, Hereditary spastic paraplegia 45 |
| RS759725715 |
PDZD7
|
Health Risk |
Conflicting classifications of pathogenicity |
PDZD7-related disorder, PDZD7-related disorder |
| RS759727498 |
LAMA2
|
Health Risk |
Likely pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS759727721 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS759727960 |
DNAH1
|
Health Risk |
Pathogenic |
Spermatogenic failure 18, Ciliary dyskinesia |
| RS759728549 |
TP53
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Li-Fraumeni syndrome |
| RS759728732 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS759729258 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Polyps |
| RS759730085 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759732362 |
FANCD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group D2 |
| RS759732945 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS759734767 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome |
| RS759736399 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS759736443 |
CYP21A2
|
Health Risk |
Pathogenic |
— |
| RS759736526 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Melanoma-pancreatic cancer syndrome |
| RS759736838 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS759737599 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759737641 |
RTTN
|
Health Risk |
Pathogenic |
— |
| RS759739044 |
COL4A3
|
Health Risk |
Likely pathogenic |
Autosomal dominant Alport syndrome, Benign familial hematuria |
| RS759739482 |
RETREG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS759739899 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS759740402 |
OCA2
|
Health Risk |
Likely pathogenic |
Nonsyndromic Oculocutaneous Albinism, Nonsyndromic Oculocutaneous Albinism |
| RS759740734 |
GRIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic X-linked intellectual disability 94, Thyroid cancer |
| RS759741090 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS759743089 |
RPGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759743111 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS759743897 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Peutz-Jeghers syndrome |
| RS759745220 |
BVES
|
Health Risk |
Likely pathogenic |
— |
| RS759746440 |
TMEM67
|
Health Risk |
Likely pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS759746669 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 5, primary |
| RS759746961 |
CNGB3
|
Health Risk |
Pathogenic |
— |
| RS759747476 |
DNMT3A
|
Health Risk |
Likely pathogenic |
Autism spectrum disorder, Autism spectrum disorder |
| RS759748510 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS759748655 |
TTBK1
|
Health Risk |
Likely pathogenic |
Childhood-onset schizophrenia, Childhood-onset schizophrenia |
| RS759748892 |
CNGB3
|
Health Risk |
Pathogenic/Likely pathogenic |
Achromatopsia 3, Achromatopsia 3 |
| RS759749364 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS759749626 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Familial cancer of breast |
| RS759751670 |
OBSCN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759752477 |
PRPH2
|
Health Risk |
Pathogenic |
Pigmentary retinal dystrophy, PRPH2-related disorder |
| RS759753811 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Seizures, benign familial infantile |
| RS759754319 |
SI
|
Health Risk |
Conflicting classifications of pathogenicity |
Sucrase-isomaltase deficiency, SI-related disorder |
| RS759754640 |
CEP78
|
Health Risk |
Pathogenic |
Cone-rod dystrophy and hearing loss 1, Cone-rod dystrophy and hearing loss 1 |
| RS759754878 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Inborn genetic diseases |
| RS759758484 |
ALPL
|
Health Risk |
Pathogenic/Likely pathogenic |
Childhood hypophosphatasia, Hypophosphatasia |
| RS759759863 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS759760029 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS759760077 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS759760533 |
POLR1C
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759761559 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS759761847 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS759761851 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759761915 |
USB1
|
Health Risk |
Pathogenic |
Poikiloderma with neutropenia, Poikiloderma with neutropenia |
| RS759762840 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS759763539 |
JAG1
|
Health Risk |
Pathogenic |
Alagille syndrome due to a JAG1 point mutation, Alagille syndrome due to a JAG1 point mutation |
| RS759763673 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, BBS1-related disorder |
| RS759763823 |
UAP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759764582 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS759764709 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS759766243 |
WWOX
|
Health Risk |
Pathogenic/Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS759767381 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759767392 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS759768852 |
SLC34A3
|
Health Risk |
Likely pathogenic |
Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease |
| RS759771909 |
ECHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759771981 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS759775013 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS759775100 |
SAMD9
|
Health Risk |
Pathogenic |
Monosomy 7 myelodysplasia and leukemia syndrome 2, Monosomy 7 myelodysplasia and leukemia syndrome 2 |
| RS759775665 |
KCNH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, KCNH1-related disorder |
| RS759775666 |
ACADVL;DVL2
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, ACADVL-related disorder |
| RS759776061 |
KCNQ3
|
Health Risk |
Conflicting classifications of pathogenicity |
Benign neonatal seizures, KCNQ3-related disorder |
| RS75977701 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Autoinflammatory syndrome |
| RS759777823 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss, Autosomal dominant nonsyndromic hearing loss 17 |
| RS759778745 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1AA, Primary familial hypertrophic cardiomyopathy |
| RS759778893 |
FOXP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759779733 |
BRWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, X-linked 93 |
| RS759781200 |
CNGA1
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 49 |
| RS759781800 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Familial hemiplegic migraine |
| RS759781877 |
ABCC2
|
Health Risk |
Pathogenic |
Dubin-Johnson syndrome, Dubin-Johnson syndrome |
| RS759782529 |
PRDM5
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS759783486 |
WDR19
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 5, Senior-Loken syndrome 8 |
| RS759785462 |
SH3TC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 4C |
| RS759786102 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS759786446 |
ERLIN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 62, Hereditary spastic paraplegia |