| RS759395776 |
RUNX2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759395960 |
CRLS1
|
Health Risk |
Pathogenic |
Combined oxidative phosphorylation deficiency 57, Combined oxidative phosphorylation deficiency 57 |
| RS759396688 |
ASL
|
Health Risk |
Pathogenic/Likely pathogenic |
Argininosuccinate lyase deficiency, ASL-related disorder |
| RS759398314 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group I |
| RS759398718 |
PCDH19
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 9 |
| RS759399965 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS759399972 |
STK26
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759401797 |
RAG1
|
Health Risk |
Pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS759401811 |
AR
|
Health Risk |
Conflicting classifications of pathogenicity |
Androgen resistance syndrome, Kennedy disease |
| RS759402659 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 4A (Zellweger), Peroxisome biogenesis disorder |
| RS759402903 |
NPHS2
|
Health Risk |
Pathogenic |
— |
| RS759403120 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS759403157 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS759403198 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Knobloch syndrome, COL18A1-related disorder |
| RS759403525 |
KMT2E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759403696 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759405296 |
EPG5
|
Health Risk |
Pathogenic |
Vici syndrome, Vici syndrome |
| RS759405317 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Birt-Hogg-Dube syndrome, Hereditary cancer-predisposing syndrome |
| RS759405378 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS759407337 |
PRORP
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined oxidative phosphorylation deficiency 54, Combined oxidative phosphorylation deficiency 54 |
| RS759407659 |
HOGA1
|
Health Risk |
Likely pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS759408031 |
RDH12
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 13, Leber congenital amaurosis |
| RS759408401 |
RAB23
|
Health Risk |
Conflicting classifications of pathogenicity |
RAB23-related Carpenter syndrome, Carpenter syndrome |
| RS759408749 |
CLDN10
|
Health Risk |
Pathogenic |
HELIX syndrome, HELIX syndrome |
| RS759408917 |
ALS2
|
Health Risk |
Pathogenic |
Amyotrophic lateral sclerosis, Infantile-onset ascending hereditary spastic paralysis |
| RS759409255 |
CACNA1D
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759410076 |
BEST1
|
Health Risk |
Pathogenic/Likely pathogenic |
Vitelliform macular dystrophy 2, Autosomal dominant vitreoretinochoroidopathy |
| RS759410438 |
SLC16A2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS759411189 |
SLC45A2
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 4, SKIN/HAIR/EYE PIGMENTATION 5 |
| RS759411705 |
CARD9
|
Health Risk |
Conflicting classifications of pathogenicity |
Predisposition to invasive fungal disease due to CARD9 deficiency, Predisposition to invasive fungal disease due to CARD9 deficiency |
| RS759412123 |
GALK1;ITGB4
|
Health Risk |
Pathogenic |
Deficiency of galactokinase, Deficiency of galactokinase |
| RS759412460 |
ELP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial dysautonomia, Medulloblastoma |
| RS759412489 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759413136 |
SLC20A2
|
Health Risk |
Pathogenic |
— |
| RS759413488 |
PFKM
|
Health Risk |
Conflicting classifications of pathogenicity |
PFKM-related disorder, Glycogen storage disease |
| RS759413622 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS759414143 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS759414746 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS759414956 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS759415233 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Malignant tumor of breast |
| RS759415304 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS759415396 |
BRWD3
|
Health Risk |
Conflicting classifications of pathogenicity |
BRWD3-related disorder, BRWD3-related disorder |
| RS759415592 |
TRAPPC11
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type R18, Autosomal recessive limb-girdle muscular dystrophy type R18 |
| RS759416152 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS759416272 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS759416890 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, Inborn genetic diseases |
| RS759417413 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS759417883 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Donnai-Barrow syndrome |
| RS759420180 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS759420443 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS75942058 |
DBH
|
Health Risk |
Conflicting classifications of pathogenicity |
Orthostatic hypotension 1, DBH-related disorder |
| RS759421771 |
FREM2
|
Health Risk |
Likely pathogenic |
— |
| RS759423600 |
BMPR1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Acromesomelic dysplasia 3, Type A2 brachydactyly |
| RS759423683 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS759424465 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS759425304 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS759425597 |
POLA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759426055 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS759427122 |
SLC39A7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759427879 |
LARGE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A6 |
| RS759428204 |
SKIC2
|
Health Risk |
Pathogenic |
— |
| RS759428783 |
F5
|
Health Risk |
Conflicting classifications of pathogenicity |
Budd-Chiari syndrome, Factor V deficiency |
| RS759430430 |
YARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate C, Inborn genetic diseases |
| RS759430551 |
MYO7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 2, Autosomal dominant nonsyndromic hearing loss 11 |
| RS759430873 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 7, Singleton-Merten syndrome 1 |
| RS759431249 |
PEX13
|
Health Risk |
Pathogenic |
Peroxisome biogenesis disorder 11A (Zellweger), Peroxisome biogenesis disorder 11A (Zellweger) |
| RS759432194 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS759432278 |
MPZL2
|
Health Risk |
Pathogenic |
Hearing loss, autosomal recessive 111 |
| RS759432455 |
FZD4
|
Health Risk |
Likely pathogenic |
Familial exudative vitreoretinopathy, Familial exudative vitreoretinopathy |
| RS759432675 |
GORAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759432908 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Hereditary spastic paraplegia |
| RS759433028 |
GALC
|
Health Risk |
Conflicting classifications of pathogenicity |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS759433119 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinal dystrophy |
| RS759434738 |
FBLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Tip-toe gait, Tip-toe gait |
| RS759435977 |
HGD
|
Health Risk |
Likely pathogenic |
Alkaptonuria, Alkaptonuria |
| RS759436020 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Skeletal overgrowth-craniofacial dysmorphism-hyperelastic skin-white matter lesions syndrome, Basal ganglia calcification |
| RS759436987 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome, Macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome |
| RS759437344 |
ABCB7
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCB7-related disorder, Inborn genetic diseases |
| RS759438521 |
SLC26A2
|
Health Risk |
Likely pathogenic |
Achondrogenesis, type IB |
| RS759439479 |
PKHD1
|
Health Risk |
Likely pathogenic |
— |
| RS759439688 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS759439914 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hematuria, benign familial |
| RS759441164 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS759441332 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS759442213 |
DDX3X
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS759442615 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS759443302 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS759445496 |
ADA
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe combined immunodeficiency, autosomal recessive |
| RS759447711 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759448397 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS759448571 |
DNMT3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Centromeric instability of chromosomes 1, 9 and 16 and immunodeficiency |
| RS759448855 |
GLI1
|
Health Risk |
Likely pathogenic |
— |
| RS759449685 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia 48 |
| RS759449765 |
MANBA
|
Health Risk |
Pathogenic/Likely pathogenic |
Beta-D-mannosidosis, Beta-D-mannosidosis |
| RS759451054 |
DMXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759451349 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hereditary spastic paraplegia 11 |
| RS759451802 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759452074 |
SCO2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardioencephalomyopathy, fatal infantile |
| RS759452442 |
COL4A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759452636 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |