| RS758716466 |
NPHP3
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis, Nephronophthisis 3 |
| RS758717223 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS758718347 |
ADGRV1
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Febrile seizures |
| RS758718496 |
LIAS
|
Health Risk |
Pathogenic |
Lipoic acid synthetase deficiency, Lipoic acid synthetase deficiency |
| RS758718584 |
NDRG1
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS758718732 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS758719615 |
NEXMIF
|
Health Risk |
Pathogenic |
Continuous spike and waves during slow sleep, X-linked intellectual disability |
| RS758719669 |
RNASEH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 4, Inborn genetic diseases |
| RS758719852 |
GGCX
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitamin K-dependent clotting factors, combined deficiency of |
| RS758720475 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS758721847 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS758722968 |
PRPF6
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS758723288 |
ECHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency, ECHS1-related disorder |
| RS758723407 |
CRB1
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 8, Leber congenital amaurosis 8 |
| RS758724746 |
CPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital hyperammonemia, type I |
| RS758725010 |
POC1B
|
Health Risk |
Likely pathogenic |
Cone-rod dystrophy 20, Cone-rod dystrophy 20 |
| RS758725073 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS758725402 |
FGF23
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS758725993 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS758726044 |
BEST1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS758726258 |
TLK2
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal dominant 57 |
| RS758727451 |
D2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
D-2-hydroxyglutaric aciduria 1, D-2-hydroxyglutaric aciduria 1 |
| RS758727749 |
HPDL
|
Health Risk |
Likely pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS758728429 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS758728491 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS758728749 |
PRF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis, Familial hemophagocytic lymphohistiocytosis 2 |
| RS758729806 |
GPNMB
|
Health Risk |
Pathogenic/Likely pathogenic |
Amyloidosis, primary localized cutaneous |
| RS758730453 |
BBS10
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS758731318 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, Wolfram syndrome 1 |
| RS758732038 |
BRCA2
|
Health Risk |
Likely pathogenic |
Hereditary breast ovarian cancer syndrome, Familial cancer of breast |
| RS758732081 |
BBS10
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS758732107 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS758732551 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS758732755 |
DMPK
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758733024 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 39 |
| RS758733242 |
GPSM2
|
Health Risk |
Likely pathogenic |
— |
| RS758733846 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS758733887 |
TCTN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Orofacial-digital syndrome IV, Joubert syndrome 18 |
| RS75873440 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial medullary thyroid carcinoma, Multiple endocrine neoplasia |
| RS758736270 |
NDUFAF5
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 16 |
| RS758736477 |
HPS3
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome 3 |
| RS758737171 |
GCK
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Permanent neonatal diabetes mellitus |
| RS758737233 |
CUL7
|
Health Risk |
Pathogenic |
3-M syndrome, 3-M syndrome |
| RS758738191 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS758739455 |
PEX16
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Peroxisome biogenesis disorder |
| RS758739748 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758739930 |
CYP27A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS758740269 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS758740850 |
ACSF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS758742595 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Nemaline myopathy 2 |
| RS758743247 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS758744263 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Diabetes mellitus, transient neonatal |
| RS758745099 |
SERAC1
|
Health Risk |
Pathogenic |
3-methylglutaconic aciduria with deafness, encephalopathy |
| RS758746181 |
EIF2B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Vanishing white matter disease, Leukoencephalopathy with vanishing white matter 1 |
| RS758746256 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
Sessile serrated polyposis cancer syndrome, Sessile serrated polyposis cancer syndrome |
| RS758746685 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Monogenic diabetes, Wolfram syndrome 1 |
| RS758748011 |
AP4S1
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 52, Spastic paraplegia |
| RS758748206 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758748280 |
CASQ2
|
Health Risk |
Pathogenic/Likely pathogenic |
Catecholaminergic polymorphic ventricular tachycardia 2, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS758748687 |
XDH
|
Health Risk |
Likely pathogenic |
Hereditary xanthinuria type 1, Hereditary xanthinuria type 1 |
| RS758749258 |
RNH1
|
Health Risk |
risk factor |
Encephalitis, acute |
| RS758749484 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS758749603 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS758750492 |
BLK
|
Health Risk |
Pathogenic |
Systemic lupus erythematosus, Systemic lupus erythematosus |
| RS758751113 |
FAM161A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 28, Retinal dystrophy |
| RS758751607 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 2, Long QT syndrome |
| RS758752052 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758752836 |
TBX5
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 2, Cardiovascular phenotype |
| RS758753292 |
GLIS3
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal diabetes mellitus with congenital hypothyroidism, Neonatal diabetes mellitus with congenital hypothyroidism |
| RS758753966 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS758754046 |
ABCC8
|
Health Risk |
Pathogenic/Likely pathogenic |
Type 2 diabetes mellitus, Type 2 diabetes mellitus |
| RS758754933 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS758755198 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, MYH9-related disorder |
| RS758755293 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS758756046 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Rubinstein-Taybi syndrome |
| RS758756630 |
SGSH
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-A |
| RS758756716 |
ABCA12
|
Health Risk |
Pathogenic |
— |
| RS758757125 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, NPHP4-related disorder |
| RS758757135 |
TWNK
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive cerebellar ataxia, Progressive external ophthalmoplegia with mitochondrial DNA deletions |
| RS758758266 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Collagen 6-related myopathy |
| RS758758729 |
ERCC2
|
Health Risk |
Likely pathogenic |
Cerebrooculofacioskeletal syndrome 2, Trichothiodystrophy 1 |
| RS758759342 |
TBC1D7
|
Health Risk |
Pathogenic |
Macrocephaly/megalencephaly syndrome, autosomal recessive |
| RS758759348 |
FKRP
|
Health Risk |
Conflicting classifications of pathogenicity |
Walker-Warburg congenital muscular dystrophy, Muscular dystrophy-dystroglycanopathy type B5 |
| RS758761887 |
KIF11
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758762096 |
GRIN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 6 |
| RS758762868 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Facial dysmorphism-immunodeficiency-livedo-short stature syndrome, Intrauterine growth retardation |
| RS758763241 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS758763586 |
CIB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758764353 |
SCN4B
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 10, Long QT syndrome 10 |
| RS758764445 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS758765095 |
MOCS1
|
Health Risk |
Pathogenic |
Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A, Sulfite oxidase deficiency due to molybdenum cofactor deficiency type A |
| RS758765126 |
MAN2B1
|
Health Risk |
Likely pathogenic |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS758765842 |
GLE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal arthrogryposis-anterior horn cell disease syndrome, Lethal congenital contracture syndrome 1 |
| RS758766818 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS758768503 |
NDUFAF5
|
Health Risk |
Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 16 |
| RS758769193 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS758769842 |
EYS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758771584 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome |
| RS758773114 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS758774720 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Tip-toe gait, Glycogen storage disease |