| RS758542902 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS758543218 |
ALDH18A1
|
Health Risk |
Pathogenic |
Autosomal dominant spastic paraplegia type 9, de Barsy syndrome |
| RS758543580 |
TCF12
|
Health Risk |
Pathogenic |
TCF12-related craniosynostosis, TCF12-related craniosynostosis |
| RS758546167 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Endometrial carcinoma |
| RS758546717 |
TBRG1
|
Health Risk |
Likely pathogenic |
Intellectual disability, Intellectual disability |
| RS758546951 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 4, RASopathy |
| RS758547221 |
HPS4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 4, Hermansky-Pudlak syndrome 4 |
| RS758547965 |
RPGRIP1L
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Joubert syndrome |
| RS758548498 |
BBS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 2 |
| RS758549770 |
NPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Acromesomelic dysplasia 1, Maroteaux type |
| RS758549961 |
ASPM
|
Health Risk |
Pathogenic |
Microcephaly 5, primary |
| RS758550101 |
NDP
|
Health Risk |
Pathogenic |
— |
| RS758550328 |
GYS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease due to muscle and heart glycogen synthase deficiency, Glycogen storage disease due to muscle and heart glycogen synthase deficiency |
| RS758550330 |
RPE65
|
Health Risk |
Pathogenic/Likely pathogenic |
Leber congenital amaurosis 2, Retinitis pigmentosa 20 |
| RS758550675 |
CEP290
|
Health Risk |
Pathogenic |
Joubert syndrome 5, Nephronophthisis |
| RS758550765 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS758551389 |
SERPINF1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta, Osteogenesis imperfecta |
| RS758551462 |
NIPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Hereditary spastic paraplegia 6 |
| RS758551684 |
PPA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Sudden cardiac failure |
| RS758551913 |
ITGB4
|
Health Risk |
Pathogenic/Likely pathogenic |
Junctional epidermolysis bullosa with pyloric atresia, Junctional epidermolysis bullosa with pyloric atresia |
| RS758551997 |
TELO2
|
Health Risk |
Conflicting classifications of pathogenicity |
TELO2-related intellectual disability-neurodevelopmental disorder, TELO2-related intellectual disability-neurodevelopmental disorder |
| RS758552293 |
FHL1
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked myopathy with postural muscle atrophy, Cardiovascular phenotype |
| RS758552587 |
KERA
|
Health Risk |
Pathogenic |
KERA-related disorder, KERA-related disorder |
| RS758553530 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Aortic aneurysm |
| RS758553809 |
BRAF
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS758553918 |
DPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of glycosylation type 1E, Congenital disorder of glycosylation type 1E |
| RS758554049 |
COLQ
|
Health Risk |
Likely pathogenic |
Congenital myasthenic syndrome 5, Synaptic congenital myasthenic syndromes |
| RS758554896 |
RFX3
|
Health Risk |
Likely pathogenic |
— |
| RS758555088 |
USH1C
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 1C, Autosomal recessive nonsyndromic hearing loss 18A |
| RS758555274 |
KMT2D
|
Health Risk |
Pathogenic |
— |
| RS758555346 |
ADAMTS17
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani 4 syndrome, recessive |
| RS758555433 |
CD19
|
Health Risk |
Likely pathogenic |
Inherited Immunodeficiency Diseases, Inherited Immunodeficiency Diseases |
| RS758555487 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS758555741 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS758557098 |
MYO15A
|
Health Risk |
Pathogenic |
— |
| RS758557229 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 5 |
| RS758557526 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS758558608 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS758558609 |
NPHP3
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis, NPHP3-related disorder |
| RS758558970 |
GNPTAB
|
Health Risk |
Likely pathogenic |
Pseudo-Hurler polydystrophy, Mucolipidosis type II |
| RS758560911 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758561093 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS758561213 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS758561541 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Dyskeratosis congenita |
| RS758561591 |
SERPING1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758561622 |
CACNA2D1
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS758561884 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS758562003 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758562288 |
DIAPH1
|
Health Risk |
Likely pathogenic |
DIAPH1-related disorder, DIAPH1-related disorder |
| RS758563983 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS758564326 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS758564871 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS758564937 |
GALE
|
Health Risk |
Likely pathogenic |
UDPglucose-4-epimerase deficiency, UDPglucose-4-epimerase deficiency |
| RS758565569 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758566439 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Arrhythmogenic right ventricular dysplasia 2 |
| RS758567108 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 17, Orofaciodigital syndrome type 6 |
| RS758567247 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS758567660 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS758568142 |
ABCA12
|
Health Risk |
Likely pathogenic |
Autosomal recessive congenital ichthyosis 4A, Autosomal recessive congenital ichthyosis 4A |
| RS758569568 |
ASXL3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758569834 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS758570139 |
ARID1B
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS75857070 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex, Ogna type |
| RS758570844 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS758571008 |
GJC2
|
Health Risk |
Likely pathogenic |
Hereditary spastic paraplegia 44, Hereditary spastic paraplegia 44 |
| RS758571672 |
USH2A
|
Health Risk |
Pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS758572409 |
SACS
|
Health Risk |
Pathogenic/Likely pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS758574474 |
NDUFA9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758575745 |
GLDC
|
Health Risk |
Pathogenic |
Glycine encephalopathy, Retinitis pigmentosa |
| RS758575947 |
KRAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS758576042 |
PROC
|
Health Risk |
Pathogenic/Likely pathogenic |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS758576419 |
ANK3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758577372 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency |
| RS758579805 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758579958 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS758580075 |
RYR1
|
Health Risk |
Pathogenic |
RYR1-related disorder, Congenital multicore myopathy with external ophthalmoplegia |
| RS758580558 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS758582935 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS758583548 |
RGS9BP
|
Health Risk |
Pathogenic |
Bradyopsia, Bradyopsia |
| RS758584771 |
ABCA4
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS758585834 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS758586312 |
SMAD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Familial thoracic aortic aneurysm and aortic dissection |
| RS758586599 |
EP300
|
Health Risk |
Conflicting classifications of pathogenicity |
EP300-related disorder, Rubinstein-Taybi syndrome due to EP300 haploinsufficiency |
| RS758587018 |
CHD2
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy 94, Developmental and epileptic encephalopathy 94 |
| RS758588019 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS758588310 |
BICD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures |
| RS758588319 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome, Kabuki syndrome 1 |
| RS758588684 |
WWOX
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 1 |
| RS758589013 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS758589097 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS758589172 |
TRIP11
|
Health Risk |
Pathogenic |
Achondrogenesis, type IA |
| RS758590520 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS758591562 |
RASGRP1
|
Health Risk |
Pathogenic |
— |
| RS758592774 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 8, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS758593134 |
CEP290
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Nephronophthisis |
| RS75859409 |
PRDM1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758594181 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS758595075 |
PYCR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelinating leukodystrophy 10, Hypomyelinating leukodystrophy 10 |
| RS758595508 |
DHFR;MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS758596783 |
VCP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |