| RS758352523 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758352741 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS758354862 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS758354863 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758354898 |
KDM1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758355520 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS758356262 |
MKKS
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, McKusick-Kaufman syndrome |
| RS758357594 |
TBK1
|
Health Risk |
Pathogenic |
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4, Frontotemporal dementia and/or amyotrophic lateral sclerosis 4 |
| RS758357747 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS758357853 |
PEPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758360637 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS758361270 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS758361736 |
KIF7
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, Acrocallosal syndrome |
| RS758362004 |
KMT2E
|
Health Risk |
Conflicting classifications of pathogenicity |
O'Donnell-Luria-Rodan syndrome, O'Donnell-Luria-Rodan syndrome |
| RS758362162 |
CCDC39
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758362908 |
ERCC4
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group F |
| RS758363294 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS758363727 |
LARS1
|
Health Risk |
Likely pathogenic |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS758366698 |
DIS3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Perlman syndrome, Perlman syndrome |
| RS758367100 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS758368552 |
ST3GAL5
|
Health Risk |
Conflicting classifications of pathogenicity |
GM3 synthase deficiency, Inborn genetic diseases |
| RS758368974 |
VPS13D
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive cerebellar ataxia-saccadic intrusion syndrome, Autosomal recessive cerebellar ataxia-saccadic intrusion syndrome |
| RS758369264 |
RPS7
|
Health Risk |
Conflicting classifications of pathogenicity |
Diamond-Blackfan anemia 8, Diamond-Blackfan anemia 8 |
| RS758369648 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS758370815 |
RTN2
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS758372631 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758373595 |
LMNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lipodystrophy, partial |
| RS758375129 |
WNT10B
|
Health Risk |
Pathogenic |
— |
| RS758375991 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS758376049 |
ORC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Meier-Gorlin syndrome 3, Meier-Gorlin syndrome 3 |
| RS758376967 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Tip-toe gait, Bethlem myopathy 1A |
| RS758377868 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS758378706 |
SPTA1
|
Health Risk |
Likely pathogenic |
SPTA1-related disorder, SPTA1-related disorder |
| RS758378927 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758379595 |
CLCN2
|
Health Risk |
Pathogenic |
Familial hyperaldosteronism type II, Familial hyperaldosteronism type II |
| RS758379604 |
SYNE1
|
Health Risk |
Likely pathogenic |
Autosomal recessive ataxia, Beauce type |
| RS758379697 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome |
| RS758379999 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS758380315 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Inborn genetic diseases |
| RS758380334 |
STN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758380663 |
TGM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS758381112 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS758382198 |
CDH23
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Pituitary adenoma 5 |
| RS758384536 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group A, FANCA-related disorder |
| RS758384659 |
MYO18B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758384953 |
ACVRL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Telangiectasia |
| RS758385503 |
FLCN
|
Health Risk |
Pathogenic |
Birt-Hogg-Dube syndrome, 17p11.2 microduplication syndrome |
| RS758385553 |
SPG7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS758386187 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
CREBBP-related disorder, Rubinstein-Taybi syndrome |
| RS758386212 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS758387062 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS758387065 |
MC4R
|
Health Risk |
Conflicting classifications of pathogenicity |
MC4R-related disorder, MC4R-related disorder |
| RS758387379 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS758387388 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Singleton-Merten syndrome 1, Aicardi-Goutieres syndrome 7 |
| RS758389471 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial melanoma, Hereditary cancer-predisposing syndrome |
| RS758389718 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS758390382 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS758391090 |
DYNC2H1
|
Health Risk |
Pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS758391206 |
WASHC5
|
Health Risk |
Likely pathogenic |
Ritscher-Schinzel syndrome, Hereditary spastic paraplegia 8 |
| RS758391429 |
RASGRP1
|
Health Risk |
Pathogenic |
— |
| RS758391601 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758391967 |
DNAH11
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758392186 |
CFHR5
|
Health Risk |
Likely pathogenic |
C3 glomerulonephritis, C3 glomerulonephritis |
| RS758392307 |
ATP6V1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 93, Autosomal recessive cutis laxa type 2D |
| RS758392443 |
GNA11
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 2, Familial hypocalciuric hypercalcemia 2 |
| RS758393038 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
SCN8A-related disorder, Early-infantile DEE |
| RS758393921 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS758395213 |
FBXL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS758395320 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS758395597 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS758395765 |
MYH2
|
Health Risk |
Pathogenic |
Myopathy, proximal |
| RS758396008 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758396206 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome and Noonan-related syndrome, Noonan syndrome and Noonan-related syndrome |
| RS758396296 |
C2CD3
|
Health Risk |
Likely pathogenic |
— |
| RS75839697 |
COX10
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex IV deficiency, nuclear type 1 |
| RS758397582 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiac arrhythmia |
| RS758398301 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS758398310 |
EIF2B2
|
Health Risk |
Pathogenic |
Premature ovarian insufficiency, Premature ovarian insufficiency |
| RS758398497 |
ARSL
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked chondrodysplasia punctata 1, Inborn genetic diseases |
| RS758398877 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brittle cornea syndrome 1 |
| RS758399311 |
LZTR1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS758399903 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1G |
| RS758401922 |
PRR12
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS758402265 |
PEX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Zellweger spectrum disorders, Zellweger spectrum disorders |
| RS758402960 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Mitochondrial DNA depletion syndrome 4b |
| RS758403441 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Lynch syndrome 1 |
| RS758404089 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS758404336 |
PKHD1
|
Health Risk |
Pathogenic |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS758404687 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular cardiomyopathy, Duchenne muscular dystrophy |
| RS758406223 |
NPHS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS758406790 |
FAN1
|
Health Risk |
Pathogenic |
Karyomegalic interstitial nephritis, Karyomegalic interstitial nephritis |
| RS758407212 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS758408106 |
FOXRED1
|
Health Risk |
Likely pathogenic |
Leigh syndrome, Leigh syndrome |
| RS758409135 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS758409623 |
SLX4
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS758409717 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS758410389 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS758410591 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Drash syndrome, Wilms tumor 1 |
| RS758410916 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS758411198 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia, autosomal recessive |