| RS758234726 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS758235027 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, ankyrin-B-related |
| RS758236336 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 11 |
| RS758236529 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS758236584 |
CBS
|
Health Risk |
Pathogenic/Likely pathogenic |
Classic homocystinuria, Homocystinuria |
| RS758236845 |
SIX5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758238174 |
LZTR1
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS758238449 |
FANCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group E, Inborn genetic diseases |
| RS758238682 |
SCN2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial fibrillation, familial |
| RS758238787 |
NPHP3
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis, NPHP3-related disorder |
| RS758239066 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS758239190 |
C9
|
Health Risk |
Pathogenic |
— |
| RS758239327 |
RAD50
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS758239674 |
RPGRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 1, Leber congenital amaurosis 6 |
| RS758240214 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS758241731 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS758241851 |
SHOC2
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, RASopathy |
| RS758242098 |
SLC7A9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystinuria, Cystinuria |
| RS758242164 |
KANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758242204 |
ALG13
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 36 |
| RS758242849 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS758243927 |
CCDC40
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758243969 |
KANSL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Koolen-de Vries syndrome, Koolen-de Vries syndrome |
| RS758245029 |
SPR
|
Health Risk |
Likely pathogenic |
Dopa-responsive dystonia due to sepiapterin reductase deficiency, Dopa-responsive dystonia due to sepiapterin reductase deficiency |
| RS758245081 |
SGCB
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2E, Autosomal recessive limb-girdle muscular dystrophy type 2E |
| RS758245234 |
RTEL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Inborn genetic diseases |
| RS758245272 |
LMNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758245830 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758246234 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS758246723 |
BRAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal-onset encephalopathy with rigidity and seizures, Inborn genetic diseases |
| RS758246761 |
PRRT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic kinesigenic dyskinesia, Inborn genetic diseases |
| RS758246840 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Charcot-Marie-Tooth disease dominant intermediate B |
| RS758247003 |
NDUFS8
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 2 |
| RS758247804 |
RYR1
|
Health Risk |
Pathogenic |
Arthrogryposis multiplex congenita, Arthrogryposis multiplex congenita |
| RS758248236 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS758248456 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758248912 |
LPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperlipoproteinemia, type I |
| RS758250423 |
PEX10
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 6A (Zellweger), Peroxisome biogenesis disorder 6B |
| RS758250431 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS758250810 |
PMS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS758251566 |
CIB2
|
Health Risk |
Likely pathogenic |
CIB2-related disorder, CIB2-related disorder |
| RS758251652 |
SCNN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism, type IB1 |
| RS758252610 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS758252808 |
HNMT
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 51 |
| RS758253709 |
GNE
|
Health Risk |
Likely pathogenic |
GNE myopathy, GNE myopathy |
| RS758254304 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2P, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS758255768 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS758258272 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS758258471 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Noonan syndrome |
| RS758258662 |
CCDC88A
|
Health Risk |
Conflicting classifications of pathogenicity |
PEHO-like syndrome, PEHO-like syndrome |
| RS758258701 |
ZNF513
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS758259365 |
SI
|
Health Risk |
Pathogenic/Likely pathogenic |
Sucrase-isomaltase deficiency, Sucrase-isomaltase deficiency |
| RS758259853 |
ALG1
|
Health Risk |
Pathogenic |
ALG1-congenital disorder of glycosylation, ALG1-congenital disorder of glycosylation |
| RS758262369 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS758264018 |
MYH2
|
Health Risk |
Pathogenic/Likely pathogenic |
Myopathy, proximal |
| RS758265897 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome |
| RS758265909 |
AGL
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS758266841 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS758268792 |
PEX1
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder 1B, Peroxisome biogenesis disorder 1A (Zellweger) |
| RS758268866 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS758271660 |
TRMU
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS758273663 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758274229 |
ALG1
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG1-congenital disorder of glycosylation, Inborn genetic diseases |
| RS758275711 |
IL2RB
|
Health Risk |
Pathogenic |
— |
| RS758275952 |
NPHP4
|
Health Risk |
Pathogenic/Likely pathogenic |
Nephronophthisis, Nephronophthisis 4 |
| RS758276004 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS758276468 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS758276968 |
SCN8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS758277011 |
TUBGCP6
|
Health Risk |
Pathogenic |
— |
| RS758277406 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Nemaline myopathy 2, Abnormality of the musculature |
| RS758278200 |
PKLR
|
Health Risk |
Likely pathogenic |
— |
| RS758278293 |
BARD1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS758279518 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS758280185 |
TGFBR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome 1 |
| RS758280375 |
WT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Frasier syndrome, Drash syndrome |
| RS758280554 |
TRPV4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2C, Brachyrachia (short spine dysplasia) |
| RS758280625 |
IFNA14
|
Health Risk |
Likely risk allele |
Susceptibility to severe COVID-19, Susceptibility to severe COVID-19 |
| RS758281375 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758281393 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS758281815 |
CYP11B2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Corticosterone 18-monooxygenase deficiency |
| RS758282201 |
DSG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic right ventricular dysplasia 10, Arrhythmogenic right ventricular dysplasia 10 |
| RS758283022 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS758283688 |
TMEM67
|
Health Risk |
Likely pathogenic |
TMEM67-related disorder, TMEM67-related disorder |
| RS758285150 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness 1E, Congenital stationary night blindness 1E |
| RS758285438 |
RAX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cone-rod dystrophy 11, Age related macular degeneration 6 |
| RS758285552 |
PROP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Pituitary hormone deficiency, combined |
| RS758286096 |
TGM6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758286394 |
GBE1
|
Health Risk |
Pathogenic |
Glycogen storage disease, type IV |
| RS758286878 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS758287054 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS758287896 |
MYLK3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758288006 |
RAG1
|
Health Risk |
Pathogenic/Likely pathogenic |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS758288878 |
TMC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 7, Autosomal recessive nonsyndromic hearing loss 7 |
| RS758289890 |
ITGB3
|
Health Risk |
Likely pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS758289966 |
RAB3GAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Martsolf syndrome, Warburg micro syndrome 2 |
| RS758290167 |
ALAS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758290425 |
C9
|
Health Risk |
Pathogenic |
— |
| RS758290491 |
HPDL
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities, Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities |
| RS758290860 |
DHTKD1
|
Health Risk |
Pathogenic |
2-aminoadipic 2-oxoadipic aciduria, 2-aminoadipic 2-oxoadipic aciduria |
| RS758291032 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Schaaf-Yang syndrome |