| RS758116997 |
CERKL
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 26, Retinitis pigmentosa 26 |
| RS758119014 |
TYR
|
Health Risk |
Likely pathogenic |
Nonsyndromic Oculocutaneous Albinism, Nonsyndromic Oculocutaneous Albinism |
| RS758119168 |
OTX2
|
Health Risk |
Pathogenic |
Anophthalmia-microphthalmia syndrome, Anophthalmia-microphthalmia syndrome |
| RS758120141 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Familial hypobetalipoproteinemia 1 |
| RS758120346 |
ARID1B
|
Health Risk |
Pathogenic |
Coffin-Siris syndrome 1, Coffin-Siris syndrome 1 |
| RS758120380 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS758120505 |
RUNX2
|
Health Risk |
Pathogenic |
Cleidocranial dysostosis, Cleidocranial dysostosis |
| RS758121289 |
FANCD2
|
Health Risk |
Pathogenic |
Fanconi anemia complementation group D2, Fanconi anemia |
| RS758122659 |
LZTR1
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS758123382 |
SMARCD2
|
Health Risk |
Pathogenic/Likely pathogenic |
Specific granule deficiency 2, SMARCD2-related disorder |
| RS758123475 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS758124326 |
COL6A3
|
Health Risk |
Pathogenic |
— |
| RS758124360 |
SZT2
|
Health Risk |
Pathogenic |
— |
| RS758124618 |
OPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758124873 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS758125212 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Sotos syndrome |
| RS758125356 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia |
| RS758125762 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS758125850 |
CRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 7, Cone-rod dystrophy 2 |
| RS758128091 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758128094 |
BRIP1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS758128209 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, Cystic fibrosis |
| RS758128368 |
CACNA1E
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS758128446 |
PCNT
|
Health Risk |
Pathogenic |
— |
| RS758128834 |
KCNJ1
|
Health Risk |
Likely pathogenic |
Bartter syndrome, Bartter syndrome |
| RS758129253 |
WHRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 31, Usher syndrome type 2D |
| RS758131044 |
DOK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 10, Fetal akinesia deformation sequence 1 |
| RS758131126 |
GNB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate F, Inborn genetic diseases |
| RS758131874 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, CHARGE syndrome |
| RS758132052 |
BLM
|
Health Risk |
Pathogenic |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS758132730 |
RECQL
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758132799 |
GPI
|
Health Risk |
Pathogenic/Likely pathogenic |
Hemolytic anemia due to glucophosphate isomerase deficiency, Hemolytic anemia due to glucophosphate isomerase deficiency |
| RS758132842 |
PEX12
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder 3A (Zellweger), PEX12-related disorder |
| RS758133069 |
ALDOB
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary fructosuria, Hereditary fructosuria |
| RS758134774 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Developmental and epileptic encephalopathy 94 |
| RS758134778 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Muscular dystrophy |
| RS758134921 |
CEP135
|
Health Risk |
Likely pathogenic |
— |
| RS758135569 |
SLC25A13
|
Health Risk |
Pathogenic/Likely pathogenic |
Citrullinemia, type II |
| RS758136052 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS758136826 |
PAX3
|
Health Risk |
Pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS758137319 |
ETFB
|
Health Risk |
Pathogenic |
Multiple acyl-CoA dehydrogenase deficiency, Multiple acyl-CoA dehydrogenase deficiency |
| RS758137485 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS758137643 |
GCDH
|
Health Risk |
Pathogenic |
Glutaric aciduria, type 1 |
| RS758138124 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pfeiffer syndrome, Hypogonadotropic hypogonadism 2 with or without anosmia |
| RS758140794 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hereditary cancer-predisposing syndrome |
| RS758142635 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758142728 |
TCAP
|
Health Risk |
Pathogenic |
Primary familial hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy 25 |
| RS758143691 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Amyloidosis |
| RS758143705 |
KIF2A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758144859 |
ACADVL
|
Health Risk |
Pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS758146135 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS758147167 |
MYH3
|
Health Risk |
Likely pathogenic |
— |
| RS758147741 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758147990 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS758150381 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS758150843 |
RORB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758150853 |
ATP13A2
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Kufor-Rakeb syndrome |
| RS758151170 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758151481 |
DNMT3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Tatton-Brown-Rahman overgrowth syndrome, DNMT3A-related disorder |
| RS758152252 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS758153898 |
TOE1
|
Health Risk |
Likely pathogenic |
Pontocerebellar hypoplasia type 7, Pontocerebellar hypoplasia type 7 |
| RS758154733 |
SDHAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pheochromocytoma and paraganglioma, Hereditary cancer-predisposing syndrome |
| RS758155107 |
DYNC2H1
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS758155716 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome |
| RS758156613 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758157294 |
KNL1
|
Health Risk |
Likely pathogenic |
Microcephaly 4, primary |
| RS758158685 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS758158889 |
INTS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Neurodevelopmental disorder with cataracts |
| RS758158942 |
GRIA3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758159521 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia |
| RS758159686 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, Autosomal dominant nonsyndromic hearing loss 17 |
| RS758161226 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS758163128 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758163506 |
MAPK7
|
Health Risk |
Pathogenic |
Scoliosis, isolated |
| RS758166013 |
HEXA
|
Health Risk |
Pathogenic/Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS758166055 |
ABAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gamma-aminobutyric acid transaminase deficiency, Gamma-aminobutyric acid transaminase deficiency |
| RS758166168 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Primary dilated cardiomyopathy |
| RS758166174 |
ABCA12
|
Health Risk |
Pathogenic |
— |
| RS758166864 |
SLC12A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Bartter disease type 1, Bartter disease type 1 |
| RS758166890 |
FKTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1X, Dilated cardiomyopathy 1X |
| RS758166967 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758166991 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS758167759 |
TBCK
|
Health Risk |
Likely pathogenic |
Hypotonia, infantile |
| RS758168827 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758169026 |
VCP
|
Health Risk |
Likely pathogenic |
Frontotemporal dementia and/or amyotrophic lateral sclerosis 6, Inclusion body myopathy with Paget disease of bone and frontotemporal dementia |
| RS758169152 |
LRP4
|
Health Risk |
Pathogenic |
Cenani-Lenz syndactyly syndrome, Congenital myasthenic syndrome 17 |
| RS758169489 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS758169847 |
USH1C
|
Health Risk |
Pathogenic |
— |
| RS758169976 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS758170522 |
IQSEC1
|
Health Risk |
Likely pathogenic |
Intellectual developmental disorder with short stature and behavioral abnormalities, Intellectual developmental disorder with short stature and behavioral abnormalities |
| RS758173527 |
HARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 3B, Usher syndrome type 3B |
| RS75817442 |
SMC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 3, Inborn genetic diseases |
| RS758175953 |
FLCN
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS758176077 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS758176356 |
AFF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cognitive impairment - coarse facies - heart defects - obesity - pulmonary involvement - short stature - skeletal dysplasia syndrome, AFF4-related disorder |
| RS758179285 |
MEGF8
|
Health Risk |
Pathogenic |
MEGF8-related Carpenter syndrome, MEGF8-related Carpenter syndrome |
| RS758180192 |
ATP8B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 1, Progressive familial intrahepatic cholestasis type 1 |
| RS758180621 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758180890 |
DYSF
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Distal myopathy with anterior tibial onset |
| RS758181047 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |