| RS758412337 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758412400 |
HOGA1
|
Health Risk |
Pathogenic |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS758412930 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, VPS13B-related disorder |
| RS758413354 |
SORL1
|
Health Risk |
Pathogenic |
— |
| RS758413374 |
AGXT
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary hyperoxaluria, type I |
| RS758413758 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS758414053 |
ALDH7A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Pyridoxine-dependent epilepsy |
| RS758415465 |
P3H1
|
Health Risk |
Likely pathogenic |
Osteogenesis imperfecta type 8, Osteogenesis imperfecta type 8 |
| RS758416485 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS758416830 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, Zellweger spectrum disorders |
| RS758417150 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758419331 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS758419553 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS758419783 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758419807 |
PTPN23
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity, Neurodevelopmental disorder and structural brain anomalies with or without seizures and spasticity |
| RS758420618 |
COL4A1
|
Health Risk |
Likely pathogenic |
— |
| RS758420946 |
PLCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephrotic syndrome, type 3 |
| RS758422851 |
COPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autoimmune interstitial lung disease-arthritis syndrome |
| RS758423821 |
FANCG
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group G |
| RS758426529 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS758427037 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Mevalonic aciduria, Porokeratosis 3 |
| RS758428552 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS758428763 |
MPL
|
Health Risk |
Pathogenic/Likely pathogenic |
MPL-related disorder, Congenital amegakaryocytic thrombocytopenia |
| RS758428843 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL11A1-related disorder, Inborn genetic diseases |
| RS758429613 |
EDA
|
Health Risk |
Likely pathogenic |
Hypohidrotic X-linked ectodermal dysplasia, Hypohidrotic X-linked ectodermal dysplasia |
| RS758430398 |
GALT
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase, Deficiency of UDPglucose-hexose-1-phosphate uridylyltransferase |
| RS758431206 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758431534 |
TAB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758432113 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS758432190 |
NLRC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Periodic fever-infantile enterocolitis-autoinflammatory syndrome, Familial cold autoinflammatory syndrome 4 |
| RS758432471 |
GNB1
|
Health Risk |
Pathogenic |
Seizure, Hypotonia |
| RS758432802 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS758434537 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS758435453 |
ANO6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758437499 |
OTOGL
|
Health Risk |
Pathogenic/Likely pathogenic |
OTOGL-related disorder, OTOGL-related disorder |
| RS758437568 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 4, Hereditary cancer-predisposing syndrome |
| RS758437737 |
TRIP11
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IA |
| RS758437810 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyper-IgE recurrent infection syndrome 3, autosomal recessive |
| RS758437844 |
TGM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 1, Autosomal recessive congenital ichthyosis 1 |
| RS758437925 |
POLR3B
|
Health Risk |
Likely pathogenic |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism |
| RS758437949 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758438414 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS758439379 |
GALNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-IV-A |
| RS758439420 |
ERCC2
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group D |
| RS75843969 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS758440368 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS758440592 |
AAAS
|
Health Risk |
Likely pathogenic |
Glucocorticoid deficiency with achalasia, Glucocorticoid deficiency with achalasia |
| RS758442518 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal dominant 2 |
| RS758442604 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS758442993 |
FN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glomerulopathy with fibronectin deposits 2, Spondylometaphyseal dysplasia - Sutcliffe type |
| RS758444182 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Alport syndrome, Alport syndrome |
| RS758444909 |
SIX5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758445380 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS75844637 |
COX10
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex IV deficiency, nuclear type 1 |
| RS758446922 |
NLRC5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758447354 |
CBS
|
Health Risk |
Conflicting classifications of pathogenicity |
Classic homocystinuria, HYPERHOMOCYSTEINEMIA |
| RS758447515 |
GBA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gaucher disease, Gaucher disease type I |
| RS758447768 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Duchenne muscular dystrophy |
| RS758448998 |
SRPX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Rolandic epilepsy, intellectual disability |
| RS758450569 |
CTSK
|
Health Risk |
Pathogenic/Likely pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS758451142 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS758452450 |
IDUA
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 1, Hurler syndrome |
| RS758452999 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS758453554 |
DCHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758453646 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS758454311 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Schaaf-Yang syndrome |
| RS758455611 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS758456073 |
WDR35
|
Health Risk |
Pathogenic |
— |
| RS758456319 |
SACS
|
Health Risk |
Pathogenic/Likely pathogenic |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS758456559 |
NCOA6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758456856 |
CLCN7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758458216 |
C7
|
Health Risk |
Pathogenic |
— |
| RS758458467 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Myopathy |
| RS758459585 |
HEXB
|
Health Risk |
Likely pathogenic |
Sandhoff disease, Sandhoff disease |
| RS758461304 |
RAC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutrophil immunodeficiency syndrome, Neutrophil immunodeficiency syndrome |
| RS758461760 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS758462343 |
F12
|
Health Risk |
Conflicting classifications of pathogenicity |
Factor XII deficiency disease, Hereditary angioedema type 3 |
| RS758462362 |
BBS9
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 9 |
| RS758462532 |
TINF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Revesz syndrome, Dyskeratosis congenita |
| RS758464032 |
FAH
|
Health Risk |
Conflicting classifications of pathogenicity |
Tyrosinemia type I, Tyrosinemia type I |
| RS758464431 |
MYO15A
|
Health Risk |
Pathogenic |
— |
| RS758464784 |
GPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilms tumor 1, Inborn genetic diseases |
| RS758465541 |
CEP57
|
Health Risk |
Conflicting classifications of pathogenicity |
Mosaic variegated aneuploidy syndrome 2, Inborn genetic diseases |
| RS758465730 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kidney disorder, Focal segmental glomerulosclerosis 5 |
| RS758465935 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS758468167 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brugada syndrome 8 |
| RS758470020 |
AFG3L2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 28, Spinocerebellar ataxia type 28 |
| RS758471372 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS758471869 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 4 |
| RS758472054 |
UQCRC2
|
Health Risk |
Likely pathogenic |
— |
| RS758472207 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 2, Cardiovascular phenotype |
| RS758472351 |
BLTP1
|
Health Risk |
Likely pathogenic |
— |
| RS758473342 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758473430 |
ASXL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758474623 |
PHF6
|
Health Risk |
Likely pathogenic |
Borjeson-Forssman-Lehmann syndrome, Nonpapillary renal cell carcinoma |
| RS758475123 |
FANCD2
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS758475317 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758476278 |
BAAT
|
Health Risk |
Pathogenic |
Bile acid conjugation defect 1, Bile acid conjugation defect 1 |
| RS758476299 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS758476981 |
USH2A
|
Health Risk |
Likely pathogenic |
— |