NLRC5 Chromosome 16
NLR family CARD domain containing 5
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What This Gene Does
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]
Gene Info
Gene Group
NLR family
Locus Type
gene with protein product
Location
16q13
Ensembl
ENSG00000140853
Key Variants
All Variants (2)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS149735722 | Health Risk | Conflicting classifications of pathogenicity | — |
| RS758446922 | Health Risk | Conflicting classifications of pathogenicity | — |