| RS758597536 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS758597713 |
FANCI
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia complementation group I |
| RS758597880 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758598971 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS758599378 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Juvenile polyposis syndrome, Hereditary cancer-predisposing syndrome |
| RS758599662 |
ADAMTS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS758599826 |
CTNNA1
|
Health Risk |
Pathogenic |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS758599939 |
DST
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 3, localized or generalized intermediate |
| RS758600822 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758600868 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS758601634 |
PYCR1
|
Health Risk |
Pathogenic |
PYCR1-related de Barsy syndrome, PYCR1-related de Barsy syndrome |
| RS758601967 |
LAMA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome, Ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome |
| RS758602245 |
CYC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758602573 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS758603417 |
KDM6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758605716 |
FGFR2
|
Health Risk |
Conflicting classifications of pathogenicity |
FGFR2-related craniosynostosis, Levy-Hollister syndrome |
| RS758607519 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, Autoinflammatory syndrome |
| RS758608221 |
CTDP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital cataracts-facial dysmorphism-neuropathy syndrome, Congenital cataracts-facial dysmorphism-neuropathy syndrome |
| RS758609113 |
FBP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Fructose-biphosphatase deficiency, Fructose-biphosphatase deficiency |
| RS758609287 |
FBXO7
|
Health Risk |
Conflicting classifications of pathogenicity |
Parkinsonian-pyramidal syndrome, Parkinsonian-pyramidal syndrome |
| RS758610033 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758610238 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder, Inborn genetic diseases |
| RS7586110 |
UGT1A8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758611156 |
GATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Arginine:glycine amidinotransferase deficiency, Arginine:glycine amidinotransferase deficiency |
| RS758612012 |
VPS13A
|
Health Risk |
Pathogenic/Likely pathogenic |
Chorea-acanthocytosis, Chorea-acanthocytosis |
| RS758613354 |
CANT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758613718 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758613799 |
CLPB
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria, type VIIB |
| RS758613901 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS758614136 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Usher syndrome type 2A |
| RS758614807 |
CDH3
|
Health Risk |
Conflicting classifications of pathogenicity |
EEM syndrome, EEM syndrome |
| RS758615834 |
LRPPRC
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS758618182 |
FGFR3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758619186 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS758619898 |
NDUFAF6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758620411 |
LARGE1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy type B6, Muscular dystrophy-dystroglycanopathy type B6 |
| RS758620810 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PKD1-related disorder |
| RS758621800 |
WDPCP
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 15, Heart defect - tongue hamartoma - polysyndactyly syndrome |
| RS758622001 |
TTN
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS758622304 |
FKBP14
|
Health Risk |
Likely pathogenic |
Ehlers-Danlos syndrome, kyphoscoliotic type |
| RS758622317 |
TREX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 1, Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations |
| RS758622612 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS758623165 |
UBR1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS758624540 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS758625682 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS758626447 |
COL6A3
|
Health Risk |
Pathogenic |
Bethlem myopathy 1C, COL6A3-related disorder |
| RS758626716 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 17, MYH9-related disorder |
| RS758626942 |
RAD21
|
Health Risk |
Likely pathogenic |
Acute megakaryoblastic leukemia in down syndrome, Acute megakaryoblastic leukemia in down syndrome |
| RS758627758 |
SLC3A1
|
Health Risk |
Likely pathogenic |
Cystine urolithiasis, Cystinuria |
| RS758628487 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, autosomal dominant |
| RS758629218 |
SCNN1B
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS758630057 |
CNTNAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Self-limited epilepsy with centrotemporal spikes, Cortical dysplasia-focal epilepsy syndrome |
| RS758630450 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 22, Autosomal recessive nonsyndromic hearing loss 37 |
| RS758631207 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS758633284 |
ITGB3
|
Health Risk |
Pathogenic |
Glanzmann thrombasthenia, Glanzmann thrombasthenia |
| RS758633794 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS758633805 |
PIGL
|
Health Risk |
Pathogenic |
CHIME syndrome, CHIME syndrome |
| RS758634272 |
APRT
|
Health Risk |
Likely pathogenic |
Adenine phosphoribosyltransferase deficiency, Adenine phosphoribosyltransferase deficiency |
| RS75863437 |
GSS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inherited glutathione synthetase deficiency, Glutathione synthetase deficiency with 5-oxoprolinuria |
| RS758635140 |
SKIC3
|
Health Risk |
Pathogenic |
— |
| RS758636143 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, Hereditary cancer-predisposing syndrome |
| RS758636279 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary nonpolyposis colorectal neoplasms |
| RS758637006 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS758637255 |
MTMR2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS758637644 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Magenis syndrome, RAI1-related disorder |
| RS758637843 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, dilated |
| RS758639053 |
ASPM
|
Health Risk |
Likely pathogenic |
— |
| RS758640982 |
LTBP4
|
Health Risk |
Pathogenic |
— |
| RS758641318 |
ALOXE3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive congenital ichthyosis 3, Autosomal recessive congenital ichthyosis 3 |
| RS758641567 |
RAD50
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Nijmegen breakage syndrome-like disorder |
| RS758641682 |
FANCA
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia complementation group A |
| RS758642695 |
CARD14
|
Health Risk |
Conflicting classifications of pathogenicity |
Pityriasis rubra pilaris, Psoriasis 2 |
| RS758642867 |
CTSA
|
Health Risk |
Pathogenic |
Combined deficiency of sialidase AND beta galactosidase, Inborn genetic diseases |
| RS758643444 |
DNAH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ciliary dyskinesia, primary |
| RS758644748 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, PTEN hamartoma tumor syndrome |
| RS758645426 |
MKKS
|
Health Risk |
Conflicting classifications of pathogenicity |
McKusick-Kaufman syndrome, Bardet-Biedl syndrome 6 |
| RS758645617 |
SNRNP200
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS758646032 |
ALAS2
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked sideroblastic anemia 1, X-linked sideroblastic anemia 1 |
| RS758646234 |
OFD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Orofaciodigital syndrome I |
| RS758646992 |
GCDH
|
Health Risk |
Pathogenic/Likely pathogenic |
Glutaric aciduria, type 1 |
| RS758647363 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758647756 |
SGCA
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy |
| RS758648839 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Autosomal recessive nonsyndromic hearing loss 4 |
| RS758649178 |
SLC45A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758649188 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758649392 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS758650140 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758650222 |
DNAAF1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758651657 |
C5
|
Health Risk |
Conflicting classifications of pathogenicity |
Complement component 5 deficiency, Eculizumab |
| RS758653462 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Charlevoix-Saguenay spastic ataxia |
| RS758654165 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS758654750 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS758654836 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS758654948 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, SCN1B-related disorder |
| RS758654999 |
PRRT2
|
Health Risk |
Pathogenic |
Episodic kinesigenic dyskinesia, Episodic kinesigenic dyskinesia |
| RS758655119 |
HARS2
|
Health Risk |
Pathogenic |
— |
| RS758655350 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS758656481 |
ARSG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758657008 |
HAX1
|
Health Risk |
Pathogenic |
Kostmann syndrome, Kostmann syndrome |
| RS758657421 |
SLC27A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis prematurity syndrome, Ichthyosis prematurity syndrome |