| RS758657548 |
CRB1
|
Health Risk |
Likely pathogenic |
— |
| RS758657734 |
CHST6
|
Health Risk |
Conflicting classifications of pathogenicity |
Macular corneal dystrophy, Macular corneal dystrophy |
| RS758658540 |
CYP21A2
|
Health Risk |
Conflicting classifications of pathogenicity |
ADRENAL HYPERPLASIA, CONGENITAL |
| RS758659025 |
QDPR
|
Health Risk |
Conflicting classifications of pathogenicity |
Dihydropteridine reductase deficiency, Dihydropteridine reductase deficiency |
| RS758659538 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Congenital contractural arachnodactyly |
| RS758660532 |
USH2A
|
Health Risk |
Pathogenic |
Retinal dystrophy, Usher syndrome type 2A |
| RS758661085 |
WDR62
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758661378 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758661538 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS758663546 |
DNAJB6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6), Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6) |
| RS758665829 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Dilated cardiomyopathy 1S |
| RS758666194 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS758666784 |
ATR
|
Health Risk |
Conflicting classifications of pathogenicity |
Seckel syndrome 1, Inborn genetic diseases |
| RS758667255 |
NTHL1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 3 |
| RS758667297 |
GLI3
|
Health Risk |
Pathogenic |
Pallister-Hall syndrome, Pallister-Hall syndrome |
| RS758667776 |
OBSCN
|
Health Risk |
Pathogenic |
— |
| RS758668477 |
CNGB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758668666 |
IL12RB2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758669355 |
CHM
|
Health Risk |
Pathogenic |
— |
| RS758669363 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 4C |
| RS758670140 |
PIK3C2A
|
Health Risk |
Pathogenic |
— |
| RS758672583 |
SUFU
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Medulloblastoma |
| RS758672665 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS758673417 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS758673714 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS758673796 |
PTH1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Metaphyseal chondrodysplasia, Jansen type |
| RS758674093 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS758674130 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS758675397 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS758677637 |
NEK1
|
Health Risk |
Pathogenic |
Short-rib thoracic dysplasia 6 with or without polydactyly, NEK1-related disorder |
| RS758677681 |
FGFR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Craniosynostosis syndrome, Trigonocephaly 1 |
| RS758677815 |
CHEK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS758678209 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS758678450 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS758678811 |
RPGRIP1
|
Health Risk |
Pathogenic |
Cone-rod dystrophy 13, Leber congenital amaurosis 6 |
| RS758680640 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS758680661 |
DOCK6
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 2, Adams-Oliver syndrome 2 |
| RS758682063 |
PAFAH1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758682585 |
APC
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 1, Familial adenomatous polyposis 1 |
| RS758682648 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital muscular dystrophy due to partial LAMA2 deficiency, LAMA2-related muscular dystrophy |
| RS758682688 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS758683062 |
ACVRL1
|
Health Risk |
Pathogenic |
Pulmonary hypertension, primary |
| RS758683818 |
SLC12A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial hypokalemia-hypomagnesemia, Inborn genetic diseases |
| RS758684873 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS758685128 |
GALC
|
Health Risk |
Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS758685448 |
C5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758685493 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS758685548 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 1, Kabuki syndrome |
| RS758685587 |
PCDH15
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 1F, Autosomal recessive nonsyndromic hearing loss 23 |
| RS758685931 |
PLCB4
|
Health Risk |
Pathogenic |
— |
| RS758686992 |
THBD
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombomodulin-related bleeding disorder, Thrombomodulin-related bleeding disorder |
| RS758687208 |
CHRNE
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 4A, Congenital myasthenic syndrome |
| RS758687380 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated Nonsyndromic Congenital Heart Disease, Alagille syndrome due to a JAG1 point mutation |
| RS758687942 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS758688444 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS758689352 |
RAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, RASopathy |
| RS758690020 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS758690821 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS758691069 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS758691852 |
CCDC82
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndromic intellectual disability, CCDC82-Related Disorders |
| RS758692347 |
KIZ
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758692443 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS758692622 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS758693125 |
IL2RG
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked severe combined immunodeficiency, Inborn genetic diseases |
| RS758694012 |
LIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
DNA ligase IV deficiency, Multiple myeloma |
| RS758696196 |
NPAT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758696992 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS758699416 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Occult macular dystrophy, Retinal dystrophy |
| RS758699499 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Primary dilated cardiomyopathy |
| RS758699749 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS758700138 |
SGCD
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1L, Autosomal recessive limb-girdle muscular dystrophy type 2F |
| RS758700198 |
EPS8L2
|
Health Risk |
Pathogenic |
Hearing loss, autosomal recessive 106 |
| RS758701470 |
PEX3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758701595 |
NFASC
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with central and peripheral motor dysfunction, Neurodevelopmental disorder with central and peripheral motor dysfunction |
| RS758701848 |
LPIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Majeed syndrome, Majeed syndrome |
| RS758702382 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS758702550 |
SPG7
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 7, Hereditary spastic paraplegia 7 |
| RS758703098 |
CBS
|
Health Risk |
Likely pathogenic |
Classic homocystinuria, Classic homocystinuria |
| RS758703752 |
OR52I2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758705082 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, PCNT-related disorder |
| RS75870538 |
C6
|
Health Risk |
Pathogenic |
— |
| RS758705873 |
USH2A
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS758705900 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS758706191 |
ITPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inosine triphosphatase deficiency, Developmental and epileptic encephalopathy |
| RS758706329 |
HERC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758707541 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS758707781 |
CLN8
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis 8, Neuronal ceroid lipofuscinosis 8 |
| RS758708229 |
NBN
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Microcephaly |
| RS75870842 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS758708495 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS758709616 |
CYBA
|
Health Risk |
Pathogenic |
Granulomatous disease, chronic |
| RS758709668 |
MC2R
|
Health Risk |
Pathogenic/Likely pathogenic |
Glucocorticoid deficiency 1, Inborn genetic diseases |
| RS758710579 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS758711507 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS758712442 |
ARSB
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS758714256 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758714890 |
CYP11B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of steroid 11-beta-monooxygenase, Glucocorticoid-remediable aldosteronism |
| RS75871497 |
AFG2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome, AFG2A-related disorder |
| RS758715635 |
AHI1
|
Health Risk |
Likely pathogenic |
Joubert syndrome, Joubert syndrome |
| RS758716088 |
GALE
|
Health Risk |
Pathogenic |
UDPglucose-4-epimerase deficiency, UDPglucose-4-epimerase deficiency |