| RS758775001 |
LAMA2
|
Health Risk |
Pathogenic |
Merosin deficient congenital muscular dystrophy, Muscular dystrophy |
| RS758775510 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS758777360 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS758777521 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758777622 |
ABRAXAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758777667 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS758779535 |
GNAO1
|
Health Risk |
Pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS758780152 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS758780409 |
SEC23B
|
Health Risk |
Likely pathogenic |
Congenital dyserythropoietic anemia, type II |
| RS758782896 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency, Inborn genetic diseases |
| RS758784148 |
LTBP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies |
| RS758784613 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758784870 |
SLC26A3
|
Health Risk |
Pathogenic |
— |
| RS758785463 |
NAGLU
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis, MPS-III-B |
| RS758786611 |
MUC1
|
Health Risk |
Conflicting classifications of pathogenicity |
MUC1-related disorder, Inborn genetic diseases |
| RS758786727 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS758786811 |
GBE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type IV |
| RS758786846 |
CACNA1C
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Long QT syndrome |
| RS758787267 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS758788067 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS758788078 |
USH2A
|
Health Risk |
Pathogenic |
— |
| RS758788135 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Tetralogy of Fallot |
| RS758790126 |
MMAB
|
Health Risk |
Pathogenic |
Methylmalonic aciduria, cblB type |
| RS758790200 |
RECQL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS758791315 |
TBCK
|
Health Risk |
Likely pathogenic |
Hypotonia, infantile |
| RS758791658 |
PHF6
|
Health Risk |
Pathogenic |
Borjeson-Forssman-Lehmann syndrome, Intellectual disability |
| RS758792385 |
ELAC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined oxidative phosphorylation defect type 17, Intellectual disability |
| RS758793075 |
SGSH
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis, MPS-III-A |
| RS758793150 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758794256 |
SOST
|
Health Risk |
Conflicting classifications of pathogenicity |
Sclerosteosis 1, Sclerosteosis 1 |
| RS758794885 |
MCCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
3-methylcrotonyl-CoA carboxylase 2 deficiency, 3-methylcrotonyl-CoA carboxylase 2 deficiency |
| RS758794919 |
EIF2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Vanishing white matter disease, Vanishing white matter disease |
| RS758795356 |
HOGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary hyperoxaluria type 3, Primary hyperoxaluria type 3 |
| RS758795405 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS758795722 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS758795961 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Muscular dystrophy |
| RS758796005 |
FASLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune lymphoproliferative syndrome type 1, AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME |
| RS758796613 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hearing impairment, Hearing impairment |
| RS758797771 |
LIPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolman disease, Wolman disease |
| RS758797992 |
HPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hermansky-Pudlak syndrome, Hermansky-Pudlak syndrome 1 |
| RS758798716 |
GHRHR
|
Health Risk |
Pathogenic/Likely pathogenic |
Isolated growth hormone deficiency, type 4 |
| RS758799742 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758800042 |
SYNE4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 76, Autosomal recessive nonsyndromic hearing loss 76 |
| RS758800351 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS758800414 |
NALCN
|
Health Risk |
Likely pathogenic |
— |
| RS758800773 |
BRWD3
|
Health Risk |
Pathogenic |
— |
| RS758801322 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Schwartz-Jampel syndrome type 1 |
| RS758802517 |
DCDC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 66, Isolated neonatal sclerosing cholangitis |
| RS758805438 |
TMEM218
|
Health Risk |
Pathogenic |
Meckel syndrome, type 4 |
| RS758805619 |
MLPH
|
Health Risk |
Conflicting classifications of pathogenicity |
MLPH-related disorder, MLPH-related disorder |
| RS758806135 |
IKBKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe combined immunodeficiency due to IKK2 deficiency, Inborn genetic diseases |
| RS758806789 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS758807774 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758807897 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS758809498 |
GRM1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive spinocerebellar ataxia 13, Autosomal recessive spinocerebellar ataxia 13 |
| RS758811078 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS758811159 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Myopathy |
| RS758811460 |
GLRA1
|
Health Risk |
Pathogenic |
Hereditary hyperekplexia, Hereditary hyperekplexia |
| RS758812102 |
PKHD1
|
Health Risk |
Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS758813493 |
SGCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Sarcoglycanopathy, Autosomal recessive limb-girdle muscular dystrophy type 2D |
| RS758813812 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Arrhythmogenic right ventricular dysplasia 2 |
| RS758813821 |
ZIC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS758813974 |
OXCT1
|
Health Risk |
Pathogenic |
Succinyl-CoA acetoacetate transferase deficiency, Succinyl-CoA acetoacetate transferase deficiency |
| RS758814013 |
FA2H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 35, Spastic paraplegia |
| RS758814126 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS758814313 |
GNE
|
Health Risk |
Likely pathogenic |
GNE myopathy, GNE myopathy |
| RS758814921 |
AARS2
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS758815341 |
SLC52A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Brown-Vialetto-van Laere syndrome 1, Inborn genetic diseases |
| RS758815860 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS758816489 |
CLCN7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758817184 |
CIC
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 45 |
| RS758818850 |
SON
|
Health Risk |
Conflicting classifications of pathogenicity |
ZTTK syndrome, ZTTK syndrome |
| RS758820425 |
IFT80
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS758820636 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758821239 |
UBE3B
|
Health Risk |
Pathogenic |
Oculocerebrofacial syndrome, Kaufman type |
| RS758821769 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 4A, Autosomal dominant nonsyndromic hearing loss 4A |
| RS758822531 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hematuria, benign familial |
| RS758823761 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS758824243 |
HECW2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758824583 |
KDM5B
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, Intellectual disability |
| RS758825857 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intervertebral disc disorder, Fibrochondrogenesis 1 |
| RS758827458 |
SLC25A13
|
Health Risk |
Pathogenic |
Citrin deficiency, Citrullinemia |
| RS758827956 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758828226 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS758828358 |
LMBR1L
|
Health Risk |
Likely pathogenic |
DSD incomplete virilization, DSD incomplete virilization |
| RS758829036 |
CFD
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758829443 |
NPC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Niemann-Pick disease, type C1 |
| RS758830069 |
NBN
|
Health Risk |
Pathogenic |
Microcephaly, normal intelligence and immunodeficiency |
| RS758830540 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS758830997 |
CLN6
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Ceroid lipofuscinosis |
| RS758831068 |
P4HTM
|
Health Risk |
Likely pathogenic |
Hypotonia, hypoventilation |
| RS758831525 |
RP1L1
|
Health Risk |
Likely pathogenic |
— |
| RS758831830 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS758832729 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS758833609 |
NDUFA6
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 33 |
| RS758834029 |
ADGRV1
|
Health Risk |
Pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS758834729 |
TG
|
Health Risk |
Conflicting classifications of pathogenicity |
Iodotyrosyl coupling defect, Iodotyrosyl coupling defect |
| RS758835278 |
CFAP410
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS758835308 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS758835368 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Severe early-childhood-onset retinal dystrophy, ABCA4-related disorder |