| RS758836138 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 1, Familial hyperinsulinism |
| RS758838678 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS758838935 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758839801 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS758840181 |
SH3TC2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS758841233 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS758841632 |
EVC2
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS758842658 |
VPS13B
|
Health Risk |
Pathogenic |
— |
| RS758843096 |
ATM
|
Health Risk |
Likely pathogenic |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS758843908 |
BSCL2
|
Health Risk |
Pathogenic |
Congenital generalized lipodystrophy type 2, Charcot-Marie-Tooth disease type 2 |
| RS758844607 |
ABCC8
|
Health Risk |
Pathogenic |
Hyperinsulinemic hypoglycemia, familial |
| RS758845090 |
SRPX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Rolandic epilepsy, intellectual disability |
| RS758845779 |
DNMT3A
|
Health Risk |
Pathogenic |
Tatton-Brown-Rahman overgrowth syndrome, Tatton-Brown-Rahman overgrowth syndrome |
| RS758846538 |
MEN1
|
Health Risk |
Pathogenic |
Multiple endocrine neoplasia, type 1 |
| RS758847068 |
SKIC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Trichohepatoenteric syndrome 1, Trichohepatoenteric syndrome 1 |
| RS758847241 |
RAD51C
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group O, Hereditary cancer-predisposing syndrome |
| RS758847803 |
ANO5
|
Health Risk |
Likely pathogenic |
Gnathodiaphyseal dysplasia, Autosomal recessive limb-girdle muscular dystrophy type 2L |
| RS758848135 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Charcot-Marie-Tooth disease type 2 |
| RS758848783 |
CHRNA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS758848800 |
CNGB1
|
Health Risk |
Conflicting classifications of pathogenicity |
CNGB1-related retinopathy, CNGB1-related retinopathy |
| RS758849410 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-onset myopathy with fatal cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS758851721 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia complementation group J, Familial cancer of breast |
| RS758852420 |
ATM
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS758853244 |
NIPBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Cornelia de Lange syndrome 1, Inborn genetic diseases |
| RS758855122 |
ERF
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, See cases |
| RS758856471 |
FANCI
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS758857025 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Inborn genetic diseases |
| RS758857773 |
ACOX1
|
Health Risk |
Pathogenic |
Acyl-CoA oxidase deficiency, Acyl-CoA oxidase deficiency |
| RS758858303 |
PKHD1
|
Health Risk |
Likely pathogenic |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS75885959 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL4A1-related disorder, COL4A1-related disorder |
| RS758859772 |
PIDD1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder, autosomal recessive 75 |
| RS758860164 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
COL4A4-related disorder, COL4A4-related disorder |
| RS758860363 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS758861786 |
TNXB
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS758862765 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS758863136 |
KIF1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Spastic ataxia 2 |
| RS758863393 |
TRAPPC6B
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder with microcephaly, epilepsy |
| RS758863985 |
NBAS
|
Health Risk |
Pathogenic/Likely pathogenic |
Short stature-optic atrophy-Pelger-Huët anomaly syndrome, Infantile liver failure syndrome 2 |
| RS758864728 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Inborn genetic diseases |
| RS758865880 |
KYNU
|
Health Risk |
Pathogenic |
Vertebral, cardiac |
| RS758865966 |
NUP93
|
Health Risk |
Pathogenic |
Nephrotic syndrome, type 12 |
| RS758866379 |
CNNM4
|
Health Risk |
Likely pathogenic |
CNNM4-related disorder, CNNM4-related disorder |
| RS758866426 |
VPS13C
|
Health Risk |
Likely pathogenic |
Autosomal recessive early-onset Parkinson disease 23, Autosomal recessive early-onset Parkinson disease 23 |
| RS758867047 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS758867131 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS758868622 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Autoinflammatory syndrome |
| RS758868843 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS758869410 |
BRCA2
|
Health Risk |
Pathogenic |
Hereditary breast ovarian cancer syndrome, Hereditary breast ovarian cancer syndrome |
| RS758870080 |
ABAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gamma-aminobutyric acid transaminase deficiency, Gamma-aminobutyric acid transaminase deficiency |
| RS758871406 |
SH3TC2
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease type 4C, Charcot-Marie-Tooth disease type 4C |
| RS758871506 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neuroblastoma |
| RS758871507 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Inborn genetic diseases |
| RS758872535 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS758872596 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Brugada syndrome 5 |
| RS758872772 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 5 |
| RS758872814 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Central core myopathy, Congenital multicore myopathy with external ophthalmoplegia |
| RS758873284 |
VARS1
|
Health Risk |
Likely pathogenic |
— |
| RS758873844 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS758874054 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS758876038 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Inborn genetic diseases |
| RS758876727 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Deafness |
| RS758877211 |
KMT2D
|
Health Risk |
Pathogenic |
Kabuki syndrome 1, Kabuki syndrome 1 |
| RS758877243 |
NEU1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS758877832 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS758877996 |
KCNV2
|
Health Risk |
Pathogenic |
— |
| RS758878983 |
CEP290
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 14, Senior-Loken syndrome 6 |
| RS758879412 |
FAM161A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Inborn genetic diseases |
| RS758879647 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2A1 |
| RS758880377 |
FANCI;POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
POLG-related disorder, Fanconi anemia complementation group I |
| RS758881668 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant tumor of urinary bladder, Hereditary cancer-predisposing syndrome |
| RS758883150 |
ELP4
|
Health Risk |
Likely pathogenic |
Seizure, Cognitive impairment |
| RS758883183 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Norman-Roberts syndrome, Familial temporal lobe epilepsy 7 |
| RS758883184 |
OFD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Orofaciodigital syndrome I |
| RS758883383 |
BCOR
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculofaciocardiodental syndrome, Oculofaciocardiodental syndrome |
| RS758884639 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS758886187 |
CSF3R
|
Health Risk |
Likely pathogenic |
— |
| RS758886532 |
COL7A1
|
Health Risk |
Pathogenic |
Epidermolysis bullosa dystrophica, Recessive dystrophic epidermolysis bullosa |
| RS758886547 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Rubinstein-Taybi syndrome |
| RS758886651 |
DUOX2
|
Health Risk |
Pathogenic |
— |
| RS758887080 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS758887740 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Cardiomyopathy |
| RS758888137 |
RSPO2
|
Health Risk |
Pathogenic |
Humerofemoral hypoplasia with radiotibial ray deficiency, Humerofemoral hypoplasia with radiotibial ray deficiency |
| RS758888293 |
GLI1
|
Health Risk |
Likely pathogenic |
— |
| RS758888472 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Hereditary cancer-predisposing syndrome |
| RS758888662 |
MYH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, proximal |
| RS758888999 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS758889240 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 2, Inborn genetic diseases |
| RS758889557 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS758891557 |
MYH7
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypertrophic cardiomyopathy, Cardiovascular phenotype |
| RS758891825 |
RSPH3
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary ciliary dyskinesia 32, Primary ciliary dyskinesia 32 |
| RS758892087 |
ACAN
|
Health Risk |
Pathogenic |
— |
| RS758893131 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS758894409 |
OCA2
|
Health Risk |
Pathogenic/Likely pathogenic |
Tyrosinase-positive oculocutaneous albinism, SKIN/HAIR/EYE PIGMENTATION 1 |
| RS758895348 |
ADSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Adenylosuccinate lyase deficiency, Adenylosuccinate lyase deficiency |
| RS758895400 |
GLDC
|
Health Risk |
Pathogenic |
Glycine encephalopathy, Glycine encephalopathy |
| RS758895722 |
VWF
|
Health Risk |
Pathogenic |
von Willebrand disease type 1, von Willebrand disorder |
| RS758895760 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Autosomal dominant nocturnal frontal lobe epilepsy |
| RS758895846 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Familial cancer of breast |
| RS758895857 |
EMILIN1
|
Health Risk |
Pathogenic |
Arterial tortuosity, Arterial tortuosity-bone fragility syndrome |
| RS758896141 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |