| RS759037498 |
ASAH1
|
Health Risk |
Pathogenic |
— |
| RS759037691 |
TIAM1
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with language delay and seizures, Neurodevelopmental disorder with language delay and seizures |
| RS759038879 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS759039589 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS759039839 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS759040714 |
IRF7
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 39, Immunodeficiency 39 |
| RS759041100 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to CREBBP mutations, Menke-Hennekam syndrome 1 |
| RS759041924 |
NAGLU
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-B |
| RS759043037 |
SLC45A2
|
Health Risk |
Pathogenic |
Oculocutaneous albinism type 4, Oculocutaneous albinism type 4 |
| RS759043669 |
ZFYVE26
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 15, Spastic paraplegia |
| RS759043857 |
COL4A3
|
Health Risk |
Likely pathogenic |
Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome |
| RS759043861 |
MLYCD
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of malonyl-CoA decarboxylase, Deficiency of malonyl-CoA decarboxylase |
| RS759043889 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS759045497 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759045547 |
EPAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Erythrocytosis |
| RS759045816 |
HYCC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelination and Congenital Cataract, Hypomyelination and Congenital Cataract |
| RS759047530 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to CREBBP mutations, Menke-Hennekam syndrome 1 |
| RS759048090 |
PEX1
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder 1B, Peroxisome biogenesis disorder 1A (Zellweger) |
| RS759048290 |
MESD
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta, type 20 |
| RS759048462 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Cardiovascular phenotype |
| RS759048538 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Lynch syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759048539 |
KIF1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Spastic ataxia 2 |
| RS759050295 |
COG1
|
Health Risk |
Conflicting classifications of pathogenicity |
COG1 congenital disorder of glycosylation, Inborn genetic diseases |
| RS759050645 |
RETREG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |
| RS759051688 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS759052298 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS759052378 |
XPA
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum group A, Xeroderma pigmentosum group A |
| RS759052984 |
DNHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Male infertility with spermatogenesis disorder, DNHD1-related disorder |
| RS759055212 |
LAMA2
|
Health Risk |
Likely pathogenic |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS759055397 |
AP5Z1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 48, Hereditary spastic paraplegia 48 |
| RS759055581 |
TET2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency 75, Immunodeficiency 75 |
| RS759056190 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS759056367 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759057396 |
HGSNAT
|
Health Risk |
Pathogenic |
Mucopolysaccharidosis, MPS-III-C |
| RS759057929 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS759058288 |
SART3
|
Health Risk |
Likely pathogenic |
Intellectual disability, Neurodevelopmental defects and Developmental delay with 46 |
| RS759059084 |
CNTNAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal congenital contracture syndrome 7, Neuropathy |
| RS759059925 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759060233 |
CYP17A1
|
Health Risk |
Likely pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, Deficiency of steroid 17-alpha-monooxygenase |
| RS759061923 |
HIKESHI
|
Health Risk |
Likely pathogenic |
Hypomyelinating leukodystrophy 13, Hypomyelinating leukodystrophy 13 |
| RS759061964 |
MAP2K2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis-Noonan syndrome, RASopathy |
| RS759063638 |
AGA
|
Health Risk |
Pathogenic |
Aspartylglucosaminuria, Aspartylglucosaminuria |
| RS759063883 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS759064297 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome |
| RS759064817 |
ANO5
|
Health Risk |
Pathogenic |
Gnathodiaphyseal dysplasia, Autosomal recessive limb-girdle muscular dystrophy type 2L |
| RS759065536 |
NEU1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sialidosis type 2, Sialidosis type 2 |
| RS759065663 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 2, Ullrich congenital muscular dystrophy 2 |
| RS759065714 |
DYSF
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Miyoshi muscular dystrophy 1 |
| RS759066438 |
LRP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Donnai-Barrow syndrome, Donnai-Barrow syndrome |
| RS759068118 |
D2HGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
D-2-hydroxyglutaric aciduria 1, D-2-hydroxyglutaric aciduria 1 |
| RS759068540 |
GALC
|
Health Risk |
Conflicting classifications of pathogenicity |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS759068561 |
RUNX1
|
Health Risk |
Pathogenic |
Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1, Hereditary thrombocytopenia and hematologic cancer predisposition syndrome |
| RS759068569 |
FANCM
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS759069096 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS759069299 |
AARS2
|
Health Risk |
Likely pathogenic |
Leukoencephalopathy, progressive |
| RS759071081 |
NR5A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Non-obstructive azoospermia, Male infertility |
| RS759071569 |
TBC1D32
|
Health Risk |
Pathogenic |
— |
| RS759071794 |
IRF2BPL
|
Health Risk |
Likely pathogenic |
Global developmental delay, Global developmental delay |
| RS759072209 |
MME
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease axonal type 2T, Ovarian serous cystadenocarcinoma |
| RS759072451 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS759072800 |
GCK
|
Health Risk |
Pathogenic |
Maturity-onset diabetes of the young type 2, Monogenic diabetes |
| RS759073156 |
DNAH10
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 56, Spermatogenic failure 56 |
| RS75907338 |
KIF5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS759074048 |
KCNQ5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 46 |
| RS759074487 |
TK2
|
Health Risk |
Likely pathogenic |
— |
| RS759074708 |
CLCN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Leukoencephalopathy with mild cerebellar ataxia and white matter edema, Epilepsy |
| RS759074976 |
C8B
|
Health Risk |
Pathogenic |
Type II complement component 8 deficiency, Type II complement component 8 deficiency |
| RS759075251 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759075520 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 26, Distal myopathy with posterior leg and anterior hand involvement |
| RS759075595 |
NPC1
|
Health Risk |
Pathogenic |
Niemann-Pick disease, type C1 |
| RS759075971 |
FGD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Aarskog syndrome |
| RS759076157 |
GCDH
|
Health Risk |
Conflicting classifications of pathogenicity |
Glutaric aciduria, type 1 |
| RS759076549 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS759076608 |
NAGS
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperammonemia, type III |
| RS759078497 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS759079269 |
CNGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinal dystrophy |
| RS759079385 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS759079847 |
SPINK5
|
Health Risk |
Conflicting classifications of pathogenicity |
Netherton syndrome, SPINK5-related disorder |
| RS759080195 |
BRIP1
|
Health Risk |
Pathogenic |
Familial cancer of breast, Fanconi anemia complementation group J |
| RS759080581 |
TPP1
|
Health Risk |
Pathogenic |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis |
| RS759080989 |
COL1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Osteogenesis imperfecta type I |
| RS759081217 |
TPM1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759081373 |
KCNH2
|
Health Risk |
Pathogenic |
— |
| RS759081607 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS759081971 |
FERMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759082809 |
PAX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759083379 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Primary dilated cardiomyopathy |
| RS759083770 |
CDKL5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 2 |
| RS759084238 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 1, Familial hyperinsulinism |
| RS759084687 |
LAMB3
|
Health Risk |
Pathogenic/Likely pathogenic |
Junctional epidermolysis bullosa, Junctional epidermolysis bullosa |
| RS759085500 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia of anesthesia, Malignant hyperthermia |
| RS759085594 |
CPXCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759086398 |
CPT2
|
Health Risk |
Likely pathogenic |
Encephalopathy, acute |
| RS759086485 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759086770 |
TTC21B
|
Health Risk |
Pathogenic/Likely pathogenic |
Type IV short rib polydactyly syndrome, Asphyxiating thoracic dystrophy 4 |
| RS759088490 |
BBS12
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 12, Retinal dystrophy |
| RS759089960 |
YY1AP1
|
Health Risk |
Likely pathogenic |
Grange syndrome, Grange syndrome |
| RS759090170 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Inborn genetic diseases |
| RS759090799 |
STK11
|
Health Risk |
Conflicting classifications of pathogenicity |
Peutz-Jeghers syndrome, Hereditary cancer-predisposing syndrome |
| RS759091617 |
POU4F3
|
Health Risk |
Likely pathogenic |
— |