| RS759150629 |
FRAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 1, Fraser syndrome 1 |
| RS759151952 |
PMS2
|
Health Risk |
Pathogenic |
Lynch syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759152941 |
ABCG8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759153401 |
CLN8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis 8 |
| RS759153754 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL11A1-related disorder, COL11A1-related disorder |
| RS759154562 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS759155182 |
ALDH5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS759156564 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS759156674 |
POMT1
|
Health Risk |
Likely pathogenic |
— |
| RS759157268 |
PCDH12
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759157320 |
SLC25A19
|
Health Risk |
Likely pathogenic |
— |
| RS759157781 |
HEXA
|
Health Risk |
Conflicting classifications of pathogenicity |
Tay-Sachs disease, variant AB |
| RS759158029 |
TONSL
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759158371 |
ACADM
|
Health Risk |
Pathogenic/Likely pathogenic |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS759159766 |
IVD
|
Health Risk |
Pathogenic |
Isovaleryl-CoA dehydrogenase deficiency, Isovaleryl-CoA dehydrogenase deficiency |
| RS759161435 |
CASK
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, CASK-related |
| RS759162614 |
DLG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, X-linked 90 |
| RS759162929 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS759163666 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS759163719 |
TAP1
|
Health Risk |
Likely pathogenic |
MHC class I deficiency, MHC class I deficiency |
| RS759166250 |
SACS
|
Health Risk |
Pathogenic |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS759166720 |
VSX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microphthalmia, isolated |
| RS759166886 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS759167480 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS759168672 |
TFG
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary motor and sensory neuropathy, Okinawa type |
| RS759170743 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Nephronophthisis |
| RS759171140 |
TG
|
Health Risk |
Pathogenic |
— |
| RS759171890 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS759172833 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiovascular phenotype |
| RS759173369 |
TYMP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759173740 |
PITRM1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759174401 |
AP3B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hermansky-Pudlak syndrome 2, Hermansky-Pudlak syndrome 2 |
| RS759174628 |
OTOGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Autosomal recessive nonsyndromic hearing loss 84B |
| RS759174655 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS759175039 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759176072 |
MSN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759177869 |
ASAH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS759178574 |
CYP11B2
|
Health Risk |
Likely pathogenic |
Familial hypoaldosteronism, Familial hypoaldosteronism |
| RS759178651 |
HLCS
|
Health Risk |
Conflicting classifications of pathogenicity |
Holocarboxylase synthetase deficiency, Holocarboxylase synthetase deficiency |
| RS759179999 |
COL4A5
|
Health Risk |
Likely pathogenic |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS759181295 |
LMF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS759181823 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS759183382 |
PEX1
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder 1A (Zellweger), Peroxisome biogenesis disorder 1B |
| RS759183489 |
STXBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS759183842 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Tuberous sclerosis syndrome |
| RS759184240 |
IMPG2
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS759184281 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS759185809 |
BBS10
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS759185877 |
CP
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of ferroxidase, Deficiency of ferroxidase |
| RS759186574 |
DRC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 27, Respiratory ciliopathies including non-CF bronchiectasis |
| RS759186986 |
SLX4
|
Health Risk |
Likely pathogenic |
Fanconi anemia, Fanconi anemia |
| RS759187140 |
PGM3
|
Health Risk |
Pathogenic |
Immunodeficiency 23, PGM3-related disorder |
| RS759187261 |
PCDH15
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 1F, Autosomal recessive nonsyndromic hearing loss 23 |
| RS759187844 |
NSUN2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759187934 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 17, Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss |
| RS759188041 |
CPAP
|
Health Risk |
Pathogenic |
Perisylvian polymicrogyria, Lissencephaly type 3 |
| RS759188441 |
CLCN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS759188647 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS759189611 |
CDK5RAP2
|
Health Risk |
Likely pathogenic |
— |
| RS759190203 |
GCM2
|
Health Risk |
Pathogenic |
— |
| RS759190964 |
NTRK1
|
Health Risk |
Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS759192059 |
CC2D2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Joubert syndrome, Meckel-Gruber syndrome |
| RS759192320 |
DHCR7
|
Health Risk |
Conflicting classifications of pathogenicity |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS759192470 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS759192785 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyropoikilocytosis, hereditary |
| RS759192836 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS759193940 |
NPHP1
|
Health Risk |
Pathogenic |
Nephronophthisis, Nephronophthisis |
| RS759195065 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Inborn genetic diseases |
| RS759198908 |
SLC12A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypokalemia-hypomagnesemia, Familial hypokalemia-hypomagnesemia |
| RS759199684 |
VARS2
|
Health Risk |
Likely pathogenic |
— |
| RS759201321 |
KCNH1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759201338 |
CDC14A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 32, Autosomal recessive nonsyndromic hearing loss 32 |
| RS759201450 |
CPS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital hyperammonemia, type I |
| RS759201960 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Inborn genetic diseases |
| RS759202535 |
VCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary familial hypertrophic cardiomyopathy, Dilated cardiomyopathy 1W |
| RS759202870 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS759202962 |
ABCB4
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive familial intrahepatic cholestasis type 3, Low phospholipid associated cholelithiasis |
| RS759203240 |
ABAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gamma-aminobutyric acid transaminase deficiency, Gamma-aminobutyric acid transaminase deficiency |
| RS759203841 |
CUBN
|
Health Risk |
Pathogenic |
Proteinuria, chronic benign |
| RS759204703 |
POMT1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS759204814 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kufor-Rakeb syndrome, Autosomal recessive spastic paraplegia type 78 |
| RS759205757 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Distal arthrogryposis type 2B1, Freeman-Sheldon syndrome |
| RS759206588 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 5, Inborn genetic diseases |
| RS759207947 |
CDH1
|
Health Risk |
Likely pathogenic |
Cleft lip with or without cleft palate, Cleft lip with or without cleft palate |
| RS759208930 |
CYP27B1
|
Health Risk |
Likely pathogenic |
CYP27B1-related disorder, Vitamin D-dependent rickets |
| RS759209452 |
PIGP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759209767 |
ACAN
|
Health Risk |
Pathogenic |
— |
| RS759210335 |
PROP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pituitary hormone deficiency, combined |
| RS759212541 |
PLEKHG5
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronopathy, distal hereditary motor |
| RS759212867 |
KAT6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Genitopatellar syndrome, Inborn genetic diseases |
| RS759213174 |
SETX
|
Health Risk |
Pathogenic |
Spinocerebellar ataxia, autosomal recessive |
| RS759213352 |
SFTPB
|
Health Risk |
Conflicting classifications of pathogenicity |
Surfactant metabolism dysfunction, pulmonary |
| RS759213580 |
CD151
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 7, with nephropathy and deafness |
| RS759213760 |
COL9A3
|
Health Risk |
Likely pathogenic |
— |
| RS759213871 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS759213872 |
ODAD3
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 30, Primary ciliary dyskinesia 30 |
| RS759214956 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Classic or attenuated familial adenomatous polyposis |
| RS759215669 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS759215923 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS759216802 |
PDGFRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Basal ganglia calcification, idiopathic |