CHST6 Chromosome 16

Carbohydrate sulfotransferase 6
32 variants 32 Health Risk

Upload your DNA to see your personal genotypes for variants in CHST6.

What This Gene Does
The protein encoded by this gene is an enzyme that catalyzes the transfer of a sulfate group to the GlcNAc residues of keratan. Keratan sulfate helps maintain corneal transparency. Defects in this gene are a cause of macular corneal dystrophy (MCD). [provided by RefSeq, Jan 2010]
Gene Info
Gene Group
Sulfotransferases, membrane bound
Locus Type
gene with protein product
Location
16q23.1
Ensembl
ENSG00000183196
Associated Conditions (5)
Macular corneal dystrophy
Inborn genetic diseases
CHST6-related disorder
See cases
type II
Key Variants
All Variants (32)
RSID Category Clinical Significance Conditions
RS1044185449 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS121917824 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS140699573 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS1482996862 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS201743866 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Inborn genetic diseases, Macular corneal dystrophy
RS2080109094 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS373160858 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, CHST6-related disorder, Macular corneal dystrophy
RS576445739 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS758657734 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS762744897 Health Risk Conflicting classifications of pathogenicity Macular corneal dystrophy, Macular corneal dystrophy
RS1233675347 Health Risk Likely pathogenic See cases, See cases
RS1471624682 Health Risk Likely pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS753928736 Health Risk Likely pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS999246452 Health Risk Likely pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS121917822 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS1412910699 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS202175444 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS2080106267 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS2507252174 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS2507252387 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS2507253239 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS28937877 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS28937878 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS28937879 Health Risk Pathogenic Macular corneal dystrophy, type II, CHST6-related disorder
RS72547544 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS746184019 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS757912368 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS771397083 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS886052321 Health Risk Pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS2151665554 Health Risk Pathogenic/Likely pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS755563003 Health Risk Pathogenic/Likely pathogenic Macular corneal dystrophy, Macular corneal dystrophy
RS756036451 Health Risk Pathogenic/Likely pathogenic Macular corneal dystrophy, Macular corneal dystrophy
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